BINOCRIT 10,000 IU/ml Price

Overview

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This medicine contains an important and useful components, as it consists of
Epoetin alfa (Recombinant Human Erythropoietin)is available in the market in concentration

Name

Epoetin alfa (Recombinant Human Erythropoietin)

Precaution

Hypertension; history of seizures; thrombocytosis; chronic liver failure; poor renal function; ischaemic vascular disease; malignant tumours. Increased risk of thrombotic events. Monitor BP during treatment. Regularly monitor platelet counts and serum-potassium concentration. Iron deficiency, infection or inflammatory disorders, haemolysis, or aluminium intoxication will reduce efficacy. Proper dosage control is required to prevent to rapid increase in the haematocrit and haemoglobin levels. Pregnancy; lactation. Lactation: Unknown whether drug is excreted in breast milk; use with caution; avoid administering multidose vials

Indication

Anaemia of chronic renal failure, Anaemia in zidovudine-treated HIV-infected patients, Anemia related to non-myeloid malignant disease chemotherapy, To reduce the need for allogenic blood tranfusion, Anaemia of prematurity.

Contra indication

Hypersensitivity to albumin (human) or mammalian cell-derived products; uncontrolled hypertension.

Side Effect

>10% Pyrexia (10-42%),Nausea (11-35%),Hypertension (14-27%),Cough (4-26%),Vomiting (12-28%),Pruritus (12-21%),Rash (2-19%),Headache (5-18%),Arthralgias (10-16%) 1-10% Arthralgia (10%),Myalgia (10%),Stomatitis (10%),Diarrhea (9%),Dizziness (9%),Edema (9%),Fatigue (9%),Weight decrease (9%),Medical device malfunction (artificial kidney clotting during dialysis) (8%),Vascular occlusion (vascular access thrombosis) (8%),Vomiting (8%),Asthenia (7%),Chest pain (7%),Injection-site irritation (7%),Muscle spasm (7%),Upper respiratory tract infection (URTI) (7%),Urticaria (3%),Seizures (2.5%),Pulmonary embolism (1%),Respiratory tract congestion (1%)

Pregnancy Category ID

3

Mode of Action

Epoetin alfa stimulates the differentiation and proliferation of erythroid precursors, release of reticulocytes into the circulation and synthesis of cellular Hb thus regulating erythropoiesis.

Interaction

Cyclosporine, hematinic agents, drugs that decrease erythropoiesis. Potentiated by hematinic agents.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration