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Overview

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This medicine contains an important and useful components, as it consists of
Tetanus toxoidis available in the market in concentration

Name

Tetanus toxoid (Absorbed Tetanus) Vaccine

Precaution

Withhold vaccination in moderate or severe febrile illness. Pregnancy, lactation, history of Guillian-Barre syndrome.

Indication

Active immunisation against tetanus, Postexposure prophylaxis of tetanus

Contra indication

It is a contraindication to use this or any other related vaccine after a serious adverse event temporally associated with a previous dose including an anaphylactic reaction. A history of systemic allergic or neurologic reactions following a previous dose of Tetanus Toxoid is an absolute contraindication for further use. If a contraindication to using tetanus toxoid -containing preparations exists in a person who has not completed a primary immunizing course of tetanus toxoid and other than a clean, minor wound is sustained; only passive immunization should be given using TIG (Human). Elective immunization should be deferred during the course of any febrile illness or acute infection. A minor afebrile illness such as a mild upper respiratory infection should not preclude immunization. Elective immunization procedures should be deferred during an outbreak of poliomyelitis.

Side Effect

Mild inj site reactions eg transient swelling, rash, fever, malaise, tiredness, nausea, vomiting, arthralgias, pruritus, dizziness. Potentially Fatal: Anaphylactic reactions.

Pregnancy Category ID

3

Mode of Action

Tetanus toxoid adsorbed induces active immunity to the tetanus antigen by stimulating the immune system to produce specific antitoxin. They are not indicated for the treatment of active tetanus infection.

Interaction

Decreased immunologic response with concurrent immunosuppressants. Neutralisation of tetanus immune globulin and tetanus toxoid adsorbed if not given at different sites using different syringes.

Pregnancy Category Note

Tetanus toxoid has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Tetanus toxoid is only recommended for use during pregnancy when benefit outweighs risk. For prevention of neonatal tetanus, adsorbed tetanus vaccine is recommended for immunization of women of childbearing age and specially in pregnancy.

Adult Dose

Child Dose

Renal Dose

Administration