ASMANEX TWISTHALER 400mcg/Actuation Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Mometasone furoateis available in the market in concentration

Name

Mometasone Furoate

Precaution

Respiratory tract tuberculosis, untreated fungal or bacterial infections, viral or parasitic infections, ocular herpes simplex Nasal septum perforation, epistaxis, wheezing Cataracts, glaucoma, increased intraocular pressure Risk of more serious or fatal course of chickenpox and measles in susceptible individuals; avoid use in unvaccinated or immunologically unexposed children or adults Deaths from adrenal insufficiency have occurred after abrupt withdrawal of oral steroids; taper withdrawal gradually May retard growth in children Immunocompromised patients Infections of nose and pharynx, including Candida albicans Excessive use may suppress hypothalamic-pituitary-adrenal function During periods of stress or severe status asthmaticus, patient may require supplementary systemic corticosteroids immediately; carry warning card to that effect Long-term administration reduces bone mineral density

Indication

Allergic rhinitis, Nasal polyps, Asthma prophylaxis

Contra indication

Hypersensitivity, Immunosuppressed patients, Tuberculosis, Status asthmaticus or other acute asthma episode necessitating intensive measures, Known hypersensitivity to milk proteins or any other ingredients

Side Effect

>10% Headache (26%),Viral infection (14%),Pharyngitis (12%),Epistaxis (11%) 1-10% Cough (7%),Upper respiratory tract infection (6%),Dysmenorrhea (5%) Frequency Not Defined Loss of taste,Muscle soreness

Pregnancy Category ID

3

Mode of Action

Mometasone depresses the formation, release and activity of endogenous inflammatory chemical mediators (e.g. kinins, histamine, liposomal enzymes and prostaglandin). It inhibits the margination and subsequent cell migration to the injury site, reverses vascular dilatation and permeability, resulting in decreased access of cells to the area of injury.

Interaction

Increased risk of hypokalaemia with amphotericin B, potassium-wasting diuretics. Decreases hypoglycaemic effects of antidiabetic drugs. Increased serum levels with antifungals (imidazole). Increased risk of tendinopathies with fluoroquinolones.