DE-NOL 120mg price in UAE

Overview

Welcome to Dwaey, specifically on DE-NOL 120mg Tablets page.
This medicine contains an important and useful components, as it consists of Bismuth subcitrate (colloidal).
DE-NOL 120mg is available in the market in concentration 120mg/Tablet and in the form of Tablets.

YAMANOUCHI EUROPE B.V. is the producer of DE-NOL 120mg and it is imported from NETHERLANDS, The most popular alternatives of DE-NOL 120mg are listed downward .

Mode Of Action

Calcium prevents or treats negative Ca balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways. Vitamin C: Necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.

Indication

Nutritional Supplement in Osteoporosis
Calcium and vitamin C deficiency
Premenstrual syndrome
Postmenopausal problems
Increased demand for Calcium and Vitamin C
pregnancy
Lactation
Periods of rapid growth (childhood
Adolescence)
In old age
During infectious disease and convalescence.

Precaution

Patients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully. Periodic checks of plasma Calcium levels and urinary Calcium excretion should be made in patients with mild to moderate renal failure or mild hypercalciuria. In patients with a history of renal stones urinary Calcium excretion should be measured to exclude hypercalciuria. With long-term treatment it is advisable to monitor serum and urinary Calcium levels and kidney function, and reduce or stop treatment temporarily if urinary Calcium exceeds 7.5 mmol/24 hours. Lactation: Calcium enters human milk; use with caution

Side Effects

Anorexia
Constipation
Flatulence
Nausea
Vomiting
Hypercalcemia
Hypophosphatemia
Xerostomia
Acid rebound
Milk-alkali syndrome
Hypotension
Headache
Diarrhea.

Contra indication

Absolute contraindications are hypercalcaemia resulting from myeloma, bone metastases or other malignant bone disease, sarcoidosis; primary hyperparathyroidism and Vitamin-D overdosage. It is also contraindicated in severe renal failure and hypersensitivity to any of the tablet ingredients.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Calcium Carbonate: Co-administration with thiazide diuretics or vit D may lead to milk-alkali syndrome and hypercalcaemia. Decreased absorption with corticosteroids. Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn and calcium-channel blockers. Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication. Calcium Gluconate: Co-admin of high calcium doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. May potentiate digoxin toxicity. Decreases effects of calcium-channel blockers. Enhanced absorption with calcitriol (a vitamin D metabolite). Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.