ZOLOFT 50mg price in UAE

Overview

Welcome to Dwaey, specifically on ZOLOFT 50mg Tablets page.
This medicine contains an important and useful components, as it consists of Sertraline.
ZOLOFT 50mg is available in the market in concentration 50mg/Tablet and in the form of Tablets.

PFIZER PHARMA PFE GMBH is the producer of ZOLOFT 50mg and it is imported from GERMANY, The most popular alternatives of ZOLOFT 50mg are listed downward .

Mode Of Action

Sertraline has a potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to sustained activity at the postsynaptic receptor sites and improvement of depression. Reduction of serotonin turnover (in brain) also contributes to its action. Its long half-life allows once daily admin.

Indication

Major Depressive illness
Panic disorder
Premenstrual dysphoric disorder
Post-traumatic stress disorder
Obsessive-compulsive disorder
Social anxiety disorder

Precaution

Patient w/ family history of bipolar disorder, mania or hypomania; previous seizure disorder or condition predisposing to seizures (e.g. alcoholism, brain damage); angle-closure glaucoma or history of glaucoma; risk factors for uric acid nephropathy, QTc prolongation. Patient w/ concurrent systemic illness (e.g. conditions that affect metabolism or haemodynamic process). Avoid abrupt withdrawal. Renal and hepatic impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor BMI (longitudinal monitoring), height, wt, unusual behavioural changes, signs and symptoms of serotonin syndrome. Lactation Distributed into milk; use caution (AAP states effect on nursing infants is unknown but may be of concern)

Side Effects

>10% Diarrhea (13-24%)
Nausea (13-30%)
Headache (20-25%)
Insomnia (12-28%)
Ejaculation disorder (7-19%)
Dizziness (6-17%)
Dry mouth (6-16%)
Fatigue (10-16%)
Drowsiness (2-15%) 1-10% Agitation (1-6%)
Anorexia (5-10%)
Anxiety (4%)
Constipation (5-8%)
Paresthesia (2%)
Impotence (5-10%)
Sweating (< 1%)
Malaise (7-9%)
Vomiting (4%)
Pain (3-6%) Frequency Not Defined Asthenia
Back pain
Chest pain
Hypoesthesia
Increased appetite
Myalgia
Palpitations
Rhinitis
Tinnitus
Weight gain
Yawning

Contra indication

Sertraline is contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of drug. Concurrent use or w/in 14 days of discontinuation of MAOIs (e.g. linezolid or IV methylene blue). Concomitant use w/ pimozide.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

May increase risk of delirium when used with antimuscarinics. Increased risk of extrapyramidal symptoms and neuroleptic malignant syndrome when used with aripiprazole. Serum levels may be reduced by carbamazepine. Concurrent use with dihydroergotamine or linezolid may lead to serotonin syndrome. May increase serum levels of lamotrigine and risk of toxicity. May increase serum levels of olanzapine, pimozide, risperidone, methadone, clozapine and amiodarone. Plasma levels may be increased by cimetidine and ritonavir. May increase the anticoagulant activity of warfarin and acenocoumarol. Potentially Fatal: Concomitant admin with MAOIs can result in serious serotonin syndrome.