Overview

Welcome to Dwaey, specifically on XYRIO 5mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Tadalafil.
XYRIO 5mg is available in the market in concentration 5mg/Tablet and in the form of Tablets/Film-coated.

APOTEX INC. is the producer of XYRIO 5mg and it is imported from CANADA, The most popular alternatives of XYRIO 5mg are listed downward .

Mode Of Action & Indication

Tadalafil is a phosphodiesterase type-5 inhibitor.

Indication

• Erectile dysfunction
• signs and symptoms of benign prostatic hyperplasia (BPH)

Precaution

Use caution in patients with anatomic deformation of penis, cardiovascular disease, left ventricular outflow obstruction, myocardial infarction in preceding 90 days, unstable angina, angina occurring during sexual intercourse, NYHA class 2 or greater heart failure in preceding 6 months, uncontrolled arrhythmias, hypotension, uncontrolled hypertension, cerebrovascular accident in preceding 6 months, bleeding disorders, active peptic ulcer disease, liver disease, renal impairment, conditions predisposing to priapism, concomitant use of CYP3A4 inhibitors Hepatic or renal impairment; CV diseases; anatomical penile deformation; predisposition to priapism; child <18 yr. Discontinue and seek medical advice if there is sudden vision loss or decreased vision in one or both eyes or tinnitus, dizziness or sudden loss or decrease in hearing, while taking Tadalafil. Seek immediate medical advice if erection last > 4 hr.

Side Effects

• >10% Headache (11-42%)
• Myalgia (1-14%)
• Respiratory tract infection (3-13%)
• Nasopharyngitis (2-13%)
• Dyspepsia (1-13%)
• Flushing (1-13%)
• Back pain (2-12%)
• Nausea (10-11%) 1-10% Nasal congestion (<9%)
• Gastroesophageal reflux disease (1-3%)
• Hypertension (1-3%)
• Bronchitis (<2%)
• Genitourinary tract infection (<2%) <1% Amnesia
• Angina pectoris
• Arthralgia
• Change in color vision
• Conjunctival hyperemia
• Dyspnea
• Epistaxis Potentially Fatal: Stevens-Johnson syndrome
• exfoliative dermatitis
• severe cardiovascular events e.g. MI
• stroke
• sudden cardiac death;

Contra indication

Concurrent use of organic nitrates, nitrates and nitric oxide donors. Men with cardiac disease for whom sexual activity is inadvisable. Recent MI (within 90 days) or stroke (within last 6 mth), hypotension (<90/50 mm Hg), unstable angina, heart failure, uncontrolled arrhythmias or hypertension.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.