VASTAREL MR Price

Overview

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This medicine contains an important and useful components, as it consists of
Trimetazidine (as diHCl)is available in the market in concentration

Name

Trimetazidine Dihydrochloride

Precaution

Moderate renal impairment (CrCl 30-60 mL/min). Pregnancy. Patient Counselling May cause dizziness and drowsiness, if affected, do not drive or operate machinery. Although teratological studies have not shown any drug related adverse effects on the course and outcome of pregnancy, the use in pregnant women is not recommended. It is not known whetherTrimetazidine passes into breast milk or not. This medication should be used while breast feeding only if the potential benefits outweigh risks to the nursing infants.

Indication

Ischaemic heart disease, Angina pectoris; Coronary heart disease

Contra indication

Hypersensitivity to Trimetazidine Dihydrochloride.

Side Effect

Dizziness, headache, abdominal pain, dyspepsia, diarrhoea, nausea, vomiting, pruritus, rash, urticaria, asthenia. Rarely, tachycardia, palpitations, extrasystoles, orthostatic hypotension, arterial hypotension, flushing.

Pregnancy Category ID

0

Mode of Action

Trimetazidine is a cellular acting anti-ischaemic agent. It has 3 main properties by which it acts as a cytoprotective agent. It inhibits the anaerobic glycolysis and fatty acid metabolism, thus allowing only aerobic glycolysis. This action helps to restore the energy balance in the cell. It inhibits acidosis and free radical accumulation in the cell. All these action help the cell to restore the normal ionic and metabolic balance.

Interaction

MAOIs, nifedipine. May potentiate the effects of other antianginals.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration