VASODILAT 50 mg/2 ml Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Sodium nitroprussideis available in the market in concentration

Name

Sodium Nitroprusside Dihydrate

Precaution

Hypothyroidism, renal and hepatic impairment, ischaemic heart disease, impaired cerebral circulation, elderly. Monitor blood thiocyanate concentration if treatment is longer than 3 days and should not exceed 100 mcg/ml. Monitor acid-base balance, venous oxygen concentration and BP. Caution to avoid extravasation. To be diluted with sterile dextrose 5% solution before infusion. Avoid sudden withdrawal. Leber's optic atrophy, low plasma-cobalamin concentrations, impaired pulmonary function. Pregnancy and lactation.

Indication

Heart failure, Severe hypertension, Hypertensive crises

Contra indication

Hypersensitivity, compensatory hypertension.

Side Effect

Common Bradyarrhythmia, hypotension, palpitations, tachyarrhythmia Apprehension, restlessness, confusion, dizziness, headache, somnolence Rash, sweating Thyroid suppression, Injection site irritation, Muscle twitch, Oliguria, renal azotemia Serious Cardiac dysrhythmia, hemorrhage, decreased platelet aggregation, excessive hypotensive response Raised intracranial pressure, Metabolic acidosis, Bowel obstruction, Methemoglobinemia, Cyanide poisoning, Thiocyanate toxicity

Pregnancy Category ID

Mode of Action

Sodium nitroprusside is a short-acting antihypertensive that acts directly on the venous and arteriolar smooth muscle causing peripheral vasodilation, thus decreasing peripheral resistance. It is also used to reduce preload and afterload in severe heart failure.

Interaction

Additive effect when used with other antihypertensives. May prolong the fibrinolytic activity of alteplase. Risk of severe hypotension if used with phosphodiesterase inhibitors. May reduce serum digoxin levels.