Active Substance: Amoxapine.
Overview
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This medicine contains an important and useful components, as it consists of
Amoxapineis available in the market in concentration
Artesunate
Hepatic or renal insufficiency. Pregnancy and lactation. Lactation: unknown
Malaria, Schistosomiasis
Hypersensitivity.
Generally well-tolerated, Cardiotoxicity (high doses), Neurotoxicity observed in animal studies, Drug induced fever, Skin rash
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Artesunate is a potent and rapidly-acting blood schizontocide derived from the leaves of the chinese herb, Armesia annua. The exact mode of action is not clear but clinical studies have confirmed the effectiveness of artesunate in P. vivax and falciparum malaria. Unclear, may inhibit DNA replication & transcription.
Antimalarial potentiating action seen with mefloquine, primaquine and tetracycline. Additive effect with chloroquine. Antagonistic effect with pyrimethamine and sulphonamides.
Information not available