UNIFED DM Price

Overview

Welcome to Dwaey, specifically on UNIFED DM page.
This medicine contains an important and useful components, as it consists of
Pseudoephedrine HCl, Triprolidine HCl, Dextromethorphan HBris available in the market in concentration

Name

Dextromethorphan + Pseudoephedrine Hydrochloride +Triprolidine Hydrochloride

Precaution

3rd trimester of pregnancy; atopic childn; child <1 yr; sedated or debilitated patients; patients confined to supine position; history of asthma. Moderate to severe renal impairment; liver disease.

Indication

Flu, Colds, Runny nose, Dry coughs, Non-productive cough, Nasal congestion

Contra indication

Patients at risk of developing resp failure. During an acute attack. Patients receiving MAOI or for 2 wk after discontinuing them. Persistent or chronic cough.

Side Effect

Dizziness, GI disturbances.

Pregnancy Category ID

3

Mode of Action

Triprolidine is a potent competitive histamine H1-receptor antagonist with mild sedating and antimuscarinic properties. Pseudoephedrine, an alpha- and beta-adrenergic receptor agonist, mediates vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa. Dextromethorphan is a centrally acting cough suppressant which acts on the cough centre in the medulla.

Interaction

Dextromethorphan: Tricyclic antidepressants (TCAs), antipsychotics, anxiolytics and hypnotics, cimetidine, ciprofloxacin, domperidone, metoclopramide, mexiletine, CYP2D6 inhibitors, ritonavir, alcohol. Potentially Fatal: Memantine, moclobemide. Triprolidine + Pseudoephedrine: Increased BP with other sympathomimetic agents (e.g. decongestants, TCA, appetite suppressants). Reduced hypotensive effects of methyldopa, ?- and ?-adrenergic blockers. Increased side effects (e.g. somnolence, agitation) with atomoxetine. Potentially Fatal: Increased risk of hypertensive crisis with furazolidine, avoid concurrent use. Increased risk of hypertensive crisis with MAOIs; avoid concurrent use or within 2 wk after stopping MAOIs. Increased risk of psychosis with bromocriptine.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration