TRENTAL 400mg price in UAE

Overview

Welcome to Dwaey, specifically on TRENTAL 400mg Tablets page.
This medicine contains an important and useful components, as it consists of Pentoxifylline.
TRENTAL 400mg is available in the market in concentration 400mg/Tablet and in the form of Tablets.

SANOFI AVENTIS S.p.A. is the producer of TRENTAL 400mg and it is imported from ITALY, The most popular alternatives of TRENTAL 400mg are listed downward .

Mode Of Action

Pentoxifylline reduces blood viscosity by increasing deformability of leukocytes and erythrocytes; and decreasing neutrophil adhesion/activation. It also improves microcirculation and peripheral tissue oxygenation through better blood flow. It has also been used in cerebrovascular disorders.

Indication

Peripheral vascular disease

Precaution

Avoid use in patients with severe cardiac arrhythmias or acute MI. Caution when used in patients with ischaemic heart disease or hypotension. Impaired renal or hepatic function. Start at lower dose in elderly; safety and efficacy not established in children. Tablets should not be chewed, crushed or broken; swallow whole. Pregnancy, lactation. Lactation: Drug excreted in breast milk; discontinue therapy, or do not nurse

Side Effects

1-10% Nausea
Vomiting <1% Angina
Anaphylaxis
Anorexia
Aplastic anemia
Pancytopenia
Conjunctivitis
Angioedema
Aseptic meningitis
Chest pain
Leukemia
Leukopenia
Cholecystitis
Hepatitis
Seizure
Scotoma
Thrombocytopenia
Increased live enzyme Potentially Fatal: Fatal haemorrhage (cerebral and GI tract); anaphylactoid reaction.

Contra indication

Previous hypersensitivity reactions to xanthine-related products e.g. caffeine, theophylline and theobromine. Recent cerebral and/or retinal haemorrhage. Porphyria.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Concurrent use with ciprofloxacin may increase the adverse effect of pentoxifylline. Concurrent use may increase serum levels of theophylline derivatives. Potentially Fatal: May increase risk of adverse effect when used with ketorolac.