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TRANDATE 100mg Price

Active Substance: Labetalol HCl.

58
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on TRANDATE 100mg Tablets page.
This medicine contains an important and useful components, as it consists of Labetalol HCl.
TRANDATE 100mg is available in the market in concentration 100mg/Tablet and in the form of Tablets.

ASPEN BAD OLDESLOE GmbH is the producer of TRANDATE 100mg and it is imported from GERMANY, The most popular alternatives of TRANDATE 100mg are listed downward .

Mode Of Action

Labetalol competitively inhibits the adrenergic stimulation of beta-receptors w/in the myocardium, bronchial and vascular smooth muscle, and alpha1-receptors w/in vascular smooth muscle. It also has some intrinsic beta2-agonist and membrane-stabilising activity.

Indication

  • Hypertension
  • Hypotensive anaesthesia

Precaution

Phaeochromocytoma, compensated heart failure, nonallergic bronchospasm. Avoid abrupt withdrawal. DM. Hepatic impairment. Perform LFTs. Elderly. Pregnancy and lactation. Lactation: Small amounts excreted; use with caution

Side Effects

  • >10% Dizziness (1-20%)
  • Lightheadedness (1-20%)
  • Nausea (<19%)
  • Tingling sensation of scalp (4-12%)
  • Fatigue (1-11%) 1-10% Elevated serum blood urea nitrogen (BUN) (<8%)
  • Elevated serum creatinine (8%)
  • Congestion of nasal sinus (1-6%)
  • Orthostatic hypotension (1-5%)
  • Absence of ejaculation (<5%)
  • Paresthesia (<5%)
  • Elevated liver enzymes (4%)
  • Diaphoresis (<4%)
  • Edema (<2%)
  • Bronchospasm (1-2%)
  • Dyspnea (1-2%)
  • Pruritus (1%)
  • Rash (1%)
  • Altered taste sense (1%)
  • Ventricular arrhythmia (1%; IV) Frequency Not Defined Angioedema
  • Bradycardia
  • Alopecia
  • Cholestatic jaundice
  • Depression
  • Diabetes insipidus
  • Hepatitis
  • Raynaud syndrome
  • Toxic myopathy
  • Urinary retention
  • Urticaria
  • Raynaud phenomenon Potentially Fatal: Hepatic injury.

Contra indication

2nd and 3rd degree heart block, cardiogenic shock, obstructive airway disease e.g. bronchial asthma, uncompensated heart failure, severe bradycardia, sick sinus syndrome, Prinzmetal's angina, severe peripheral arterial disease.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Synergistic hypotensive effect w/ halothane. Increased absolute bioavailability w/ cimetidine. Decreased absolute bioavailability w/ glutethimide. Additive hypotensive effect w/ nitroglycerin. Increased incidence of tremor w/ TCAs. Increased risk of bradycardia and heart block w/ Ca channel blocker (e.g. verapamil, diltiazem).

Alternatives Price List

  • TRANDATE 5mg/mlUAD 67
  • TRANDATE 200mgUAD 23
  • TRANDATE 200mgUAD 84
  • TRANDATE 100mgUAD 17
  • TRANDATE 100mgUAD 58

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