Active Substance: Spectinomycin HCl.
Overview
Welcome to Dwaey, specifically on TOGAMYCIN 2g page.
This medicine contains an important and useful components, as it consists of
Spectinomycin HClis available in the market in concentration
Spectinomycin
Ineffective in the treatment of syphilis and may mask or delay symptoms of incubating syphilis. Pregnancy and lactation. Monitoring Parameters Perform serologic test for syphilis at the time of gonorrhoea diagnosis and 3 mth later.
Gonorrhoea, Acute gonorrheal urethritis, Cervicitis and proctitis
Hypersensitivity.
Nausea, dizziness, fever and chills, insomnia, urticaria, mild to moderate pain after IM inj, alterations in kidney and liver function, decrease in Hb and haematocrit. Potentially Fatal: Anaphylaxis.
2
Spectinomycin binds to 30S subunit of the bacterial ribosome, thus inhibiting protein synthesis. It has modest activity against a wide range of gm+ve and gm-ve organisms, though anaerobic organisms are mostly resistant.
May result in lithium toxicity when used concurrently. May increase or prolong the neuromuscular blocking effect of atracurium.
Information not available