Overview

Welcome to Dwaey, specifically on DELOR 0.05% Cream page.
This medicine contains an important and useful components, as it consists of Clobetasol propionate.
DELOR 0.05% is available in the market in concentration 0.5mg/g and in the form of Cream.

PHARMA INTERNATIONAL CO. is the producer of DELOR 0.05% and it is imported from JORDAN, The most popular alternatives of DELOR 0.05% are listed downward .

Mode Of Action & Indication

Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.

Indication

• Corticosteroid-responsive Dermatoses
• Psoriasis
• Scalp Psoriasis
• Plaque-type Psoriasis
• Vitiligo
• Eczema
• Alopecia areata
• Herpes labialis
• Lichen sclerosus
• Lichen
• Mycosis fungoides
• Corticosteroid-responsive dermatoses

Precaution

Long-term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily even without occlusion. If used in childhood, or on the face, courses should be limited to 5 days and occlusion should not be used. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye. If used in psoriasis careful patient supervision is important. Scalp Application: Keep away from eye. Flammable. Do not use or dry the hair near a fire or flame. Scalp Shampoo: Do not use on areas other than the scalp. Keep away from eye. Lactation: Excretion in milk unknown; use with caution

Side Effects

• Perioral dermatitis
• striae esp in flexures. Dermal and epidermal atrophy esp on the face
• steroid purpura. Burning
• Cracking/fissuring of the skin
• Erythema
• Folliculitis
• Irritation
• Numbness
• Pruritus
• Stinging
• Hypopigmentation (high potency topical steroids) Potentially Fatal: Prolonged usage of large amount of clobetasol propionate can lead to sufficient systemic levels to produce adrenal suppression
• Cushing's syndrome
• diabetes and hypertension.

Contra indication

Childn <12 yrs. Long-term treatment of ulcerative conditions, rosacea, pruritus; It is contraindicated in rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections (eg. herpes simplex, chickenpox), otitis externa with a perforated eardrum, hypersensitivity to the preparations. Scalp application is contraindicated in infection of the scalp.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks