TAXOTERE 80mg Price
Active Substance: Docetaxel (anhydrous).
Overview
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This medicine contains an important and useful components, as it consists of
Docetaxel (anhydrous)is available in the market in concentration
Name
Docetaxel
Precaution
Lactation. Hepatic impairment. Monitor liver blood function and blood counts regularly. Premedication with oral dexamethsaone at 16 mg daily for 3 days, starting one day before docetaxel treatment is recommended. Lactation: Not known if excreted in breast milk, do not nurse
Indication
Breast cancer, Lung cancer, Prostate cancer, Stomach cancer, Head/neck cancer
Contra indication
Previous severe hypersensitivity reaction to docetaxel, the solvent or polysorbate 80. Severe neutropenia; pregnancy, severe liver impairment.
Side Effect
>50% Alopecia,Anemia,Leukopenia,Neutropenia,Asthenia 10-50% Fever,Infections,Fluid retention,Hypersensitivity,Skin reactions,Diarrhea,Nausea,Vomiting,Sensory neuropathy,Myalgia,Nail changes 1-10% Arthralgia,Thrombocytopenia Potentially Fatal: Neutropenia; fluid retention syndrome; anaemia.
Pregnancy Category ID
4
Mode of Action
Docetaxel disrupts the microtubular network in cells that is essential for vital mitotic and interphase cellular functions. It binds to the free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly, resulting in inhibition of mitosis.
Interaction
CYP3A4 inducers, inhibitors, or substrates may alter docetaxel metabolism.
Pregnancy Category Note
Information not available
Adult Dose
Child Dose
Renal Dose
Administration
