SYNTHROID 300 mcg price in UAE

Overview

Welcome to Dwaey, specifically on SYNTHROID 300 mcg Tablet page.
This medicine contains an important and useful components, as it consists of Levothyroxine sodium.
SYNTHROID 300 mcg is available in the market in concentration 300 mcg/Tablet and in the form of Tablet.

ABBOTT LABORATORIES is the producer of SYNTHROID 300 mcg and it is imported from USA, The most popular alternatives of SYNTHROID 300 mcg are listed downward .

Mode Of Action

Levothyroxine Na is a synthetic form of thyroxine which increases the basal metabolic rate (BMR) and the utilisation and mobilisation of glycogen stores and stimulates protein synthesis. It is also involved in normal metabolism, growth and development. These effects are mediated at the cellular level by the thyroxine metabolite, tri-iodothyronine.

Indication

Hypothyroidism
TSH suppression
Myxoedema coma

Precaution

Patients w/ CV (e.g. angina, heart failure, HTN), DM and diabetes insipidus, epilepsy, pre-existing myasthenia syndrome, long-standing hypothyroidism. Elderly, pregnancy and lactation. Monitoring Parameters Monitor thyroid function test, clinical signs of hypo- and hyperthyroidism, heart rate and BP. Lactation: Enters breast milk; use caution

Side Effects

Nervousness
excitability
tremor
muscle weakness
fatigue
cramps; sweating
flushing
heat intolerance
headache
fever
insomnia
tachycardia
palpitations
restlessness
anginal pain
HTN
severe depression
difficulty in sleeping
excessive wt loss; menstrual irregularities; diarrhoea
vomiting
psychosis or agitation. Increased bone resorption and reduced bone mineral density
especially in post-menopausal women; elevated LFT. Potentially Fatal: Thyrotoxic crisis including convulsions
cardiac arrhythmia
heart failure
coma.

Contra indication

Untreated hyperthyroidism; uncorrected adrenal failure; recent MI.

Pregnancy and lactation

Pregnancy category: A

Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Interaction

Reduced absorption w/ iron, antacids, bile acid sequestrants, colestyramine, simeticone, Ca carbonate, sucralfate, cation exchange resins. Reduced tri-iodothyronine serum levels w/ amiodarone and propranolol. Reduced serum levels of thyroxine w/ carbamazepine, phenytoin, phenobarbital, rifampicin, lithium, oestrogens, sertraline. Androgens may decrease levothyroxine-binding globulins serum levels. May alter requirements of antidiabetic drugs. Increased risk of significant HTN and tachycardia w/ ketamine. Increased metabolic demands w/ sympathomimetics (e.g. epinephrine). May increase anticoagulant effect of warfarin.