ANECTINE (MIDARINE) 100mg price in UAE

Overview

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This medicine contains an important and useful components, as it consists of Suxamethonium chloride.
ANECTINE (MIDARINE) 100mg is available in the market in concentration 50mg/ml and in the form of Injection/Solution for.

THE WELLCOME FOUNDATION LIMITED is the producer of ANECTINE (MIDARINE) 100mg and it is imported from UK, The most popular alternatives of ANECTINE (MIDARINE) 100mg are listed downward .

Mode Of Action

Suxamethonium chloride is an ultrashort-acting depolarising type skeletal muscle relaxant. It blocks the neuromuscular junction by binding to the cholinergic receptors and depolarising it.

Indication

Muscle relaxant

Precaution

Hypersensitivity to any neuromuscular blocker. Patient w/ reduced plasma cholinesterase activity, bone fractures, neuromuscular disorders, cardiac or resp disease, electrolyte imbalance, suspected cardiac glycoside toxicity. Childn. Pregnancy and lactation. Monitoring Parameters Monitor cardiac function and oxygenation during admin; temp, serum K and Ca, assisted ventilator status; neuromuscular function w/ peripheral nerve stimulator.

Side Effects

Prolonged resp depression or apnoea
bradycardia
tachycardia
hypotension
HTN
raised intraocular pressure
hyperkalaemia
muscle fasciculation
excessive salivation
jaw rigidity
rash. Potentially Fatal: Anaphylactic and anaphylactoid reactions
acute rhabdomyolysis w/ hyperkalaemia followed by ventricular dysrhythmias and cardiac arrest
malignant hyperthermia.

Contra indication

Genetic disorders of plasma pseudocholinesterase, personal/family history of malignant hyperthermia, hypersensitivity from previous neuromuscular drug, severe burns, massive trauma, extensive denervation of skeletal muscle, patients with risk of hyperkalaemia, renal impairment, angle closure glaucoma.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Prolonged neuromuscular blocking effects w/ specific anticholinesterase agents (e.g. neostigmine), cytotoxic compd (e.g. cyclophosphamide), antiarrhythmics (e.g. quinidine), aminoglycosides, psychiatric drugs (e.g. chlorpromazine), Mg salts, anaesth agents (e.g. morphine), SSRIs, organophosphate insecticides. Increased susceptibility to the effects of suxamethonium-exacerbated hyperkalaemia w/ digitalis-like drugs.