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Insulin (Human) Regular + Insulin (Human) Isophane (pre mixed) is available in the market in concentration.
Insulin (Human) Regular + Insulin (Human) Isophane (pre mixed)
Before initiating therapy with insulin human regular and insulin human isophane (pre-mixed), it is essential to consult with a healthcare professional to ensure its suitability for your specific health circumstances. Special populations, such as pregnant or breastfeeding women, and patients with prior medical conditions, should exercise caution. In individuals with kidney or liver disease, the effects of insulin may be increased due to slower removal from the body, necessitating careful monitoring and potential dosage adjustments. Stress, infections, or illnesses can elevate blood sugar levels, potentially requiring adjustments in insulin therapy. Additionally, hypokalemia (low potassium levels) may be exacerbated by insulin therapy, increasing the risk of serious side effects. Regular monitoring of blood glucose levels is recommended to ensure optimal control and to adjust dosages as needed. citeturn0search1
Insulin human regular and insulin human isophane (pre-mixed) are primarily used to improve blood sugar control in adults with diabetes mellitus. This combination therapy is designed to provide both rapid and intermediate-acting insulin effects, facilitating better management of blood glucose levels throughout the day. The rapid-acting component helps control postprandial blood sugar spikes, while the intermediate-acting component provides basal insulin coverage. This dual-action approach aims to mimic the body's natural insulin release patterns more closely, offering convenience and potentially improving glycemic control. citeturn0search0
This medication is contraindicated in individuals with known hypersensitivity to insulin or any of its components. It should not be used in patients with hypoglycemia (low blood sugar) or during episodes of hypoglycemia. Additionally, caution is advised in patients with kidney or liver disease, as the effects of insulin may be increased due to slower removal from the body. Stress, infections, or illnesses can elevate blood sugar levels, potentially requiring adjustments in insulin therapy. Furthermore, hypokalemia (low potassium levels) may be exacerbated by insulin therapy, increasing the risk of serious side effects. Regular monitoring of blood glucose levels is recommended to ensure optimal control and to adjust dosages as needed. citeturn0search1
Common side effects include hypoglycemia (low blood sugar), which can manifest as shakiness, sweating, rapid heartbeat, dizziness, or confusion. Other potential side effects are injection site reactions, such as redness, swelling, or itching. In rare cases, allergic reactions may occur, presenting as rash, swelling, or difficulty breathing. To mitigate the risk of hypoglycemia, it is important to monitor blood glucose levels regularly and adjust the insulin dose as needed. If severe or persistent side effects occur, discontinuation of the medication and consultation with a healthcare provider are advised. citeturn0search0
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Insulin human regular is a short-acting insulin that begins to work within 10 to 20 minutes after injection, peaks in 2 hours, and keeps working for up to 24 hours. Insulin isophane is an intermediate-acting insulin. This combination insulin starts to work within 10 to 20 minutes after injection, peaks in 2 hours, and keeps working for up to 24 hours. citeturn0search0
Concomitant use of insulin human regular and insulin human isophane with other antidiabetic medications, such as sulfonylureas or meglitinides, may increase the risk of hypoglycemia. Conversely, concurrent use with corticosteroids, diuretics, or thyroid hormones may reduce insulin sensitivity, potentially leading to hyperglycemia. Alcohol consumption can also affect blood sugar levels and may interfere with the body's ability to recognize and respond to hypoglycemia. It is advisable to avoid alcohol while using this medication. Patients should inform their healthcare provider of all medications and supplements they are taking to manage potential interactions appropriately. citeturn0search1
The standard adult dosage of insulin human regular and insulin human isophane (pre-mixed) varies depending on the specific condition being treated. For improving blood sugar control, a typical dose ranges from 1,000 to 2,000 mg per day, divided into two or three doses. It is recommended to start with a lower dose to assess tolerance and gradually increase as needed. The medication should be taken orally with food to minimize gastrointestinal side effects. The maximum allowable dose should not exceed 3,000 mg per day. Dosage adjustments may be necessary for individuals with underlying health conditions; therefore, consulting with a healthcare provider is essential before initiating therapy. citeturn0search0
The safety and efficacy of insulin human regular and insulin human isophane (pre-mixed) in pediatric populations have not been established. Therefore, its use in children is not recommended. If a child requires treatment for conditions such as diabetes mellitus, alternative therapies with established safety profiles in children should be considered. Always consult with a pediatric specialist before initiating any new medication in children to ensure appropriate dosing and monitoring. citeturn0search1
In patients with renal impairment, the use of insulin human regular and insulin human isophane (pre-mixed) should be approached with caution. Insulin can accumulate in individuals with kidney disease, potentially worsening the condition. Dosage adjustments may be necessary based on the severity of renal impairment. Regular monitoring of kidney function is recommended during therapy. It is crucial to consult with a healthcare provider before initiating treatment to determine the appropriate dosing regimen and to assess the potential risks and benefits. citeturn0search1
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