background

Folic Acid + Zinc

Welcome to Dwaey, specifically on Folic Acid + Zinc page.
This medicine contains important and useful components, as it consists of
Folic Acid + Zinc is available in the market in concentration.

Generic Name of Folic Acid + Zinc - Learn More

Folic Acid + Zinc

Folic Acid + Zinc Precaution - What You Need to Know

Folic acid and zinc are vital nutrients that support various bodily functions. However, some precautions should be considered before their use, especially in specific populations or those with certain conditions.
- Pregnancy: Both folic acid and zinc are crucial during pregnancy. Folic acid is vital for preventing neural tube defects, while zinc supports fetal growth, immune function, and cell division. Pregnant women typically require 400-800 mcg of folic acid daily and 11 mg of zinc per day. Excessive zinc intake (above 40 mg per day) may interfere with copper absorption and impair immune function, so it should be used cautiously.
- Breastfeeding: These nutrients are important during breastfeeding as they support both maternal health and infant development. Folic acid, at recommended doses, and zinc should be taken to ensure adequate levels in breast milk. Zinc supplementation in excess should be avoided to prevent toxicity.
- Gastrointestinal issues: Zinc supplementation can cause nausea, stomach upset, or diarrhea, especially when taken on an empty stomach. It is advisable to take zinc with food to reduce gastrointestinal side effects.
- Kidney function: Patients with kidney disorders should use zinc cautiously, as high doses can accumulate in the body due to impaired excretion. Similarly, folic acid is usually safe but should be monitored in patients with renal impairment, as supplementation may interact with certain medications commonly prescribed to such patients.
- Interaction with medications: Zinc supplements may interfere with the absorption of certain antibiotics (e.g., tetracyclines, quinolones), and diuretics may increase zinc excretion. Patients should consult a healthcare provider before combining this supplement with medications. Excessive folic acid may mask the symptoms of vitamin B12 deficiency, leading to neurological damage if left untreated.

Folic Acid + Zinc Indication - Uses and Benefits

Folic acid and zinc are often combined in supplements to address specific nutritional deficiencies and to support general health:
- Folic acid deficiency: Folic acid supplementation is primarily used to treat and prevent folate deficiency, which can lead to megaloblastic anemia. It's also crucial in preventing birth defects like neural tube defects during pregnancy.
- Zinc deficiency: Zinc plays an essential role in immune function, wound healing, DNA synthesis, and protein synthesis. Zinc deficiency can lead to growth retardation, impaired immune function, hair loss, and delayed wound healing.
- Immune support: Zinc plays a key role in immune cell function, including the activation of T-cells and the production of antibodies. Zinc supplementation is often used to enhance immune function, particularly in populations at risk for deficiency such as the elderly, pregnant women, and those with chronic illnesses.
- Wound healing: Zinc is critical for proper wound healing, as it plays a role in collagen synthesis and cellular repair. Folic acid, while not directly involved in wound healing, supports overall cell growth and repair, which is beneficial in tissue regeneration.
- Pregnancy support: Zinc and folic acid are routinely included in prenatal vitamins due to their essential roles in fetal growth, immune support, and neural tube defect prevention. Zinc is also necessary for normal fetal development and the function of the placenta.

Folic Acid + Zinc Contraindications - Important Warnings

Certain conditions or factors may contraindicate the use of folic acid and zinc supplements:
- Excessive zinc intake: Individuals with zinc toxicity or those with a known hypersensitivity to zinc should avoid supplementation. High levels of zinc (over 40 mg per day) can cause nausea, vomiting, loss of appetite, and long-term toxicity such as copper deficiency.
- Allergy or hypersensitivity: People with a known allergy to any ingredient in the supplement (including zinc or folic acid) should avoid it.
- Iron-deficiency anemia: Zinc can interfere with the absorption of iron, which can exacerbate iron-deficiency anemia. This is especially important when both zinc and iron are being supplemented simultaneously, as the absorption of both minerals may be reduced.
- Renal impairment: In individuals with impaired kidney function, particularly chronic kidney disease, both folic acid and zinc supplements should be monitored. High doses of zinc can accumulate in the body if renal excretion is impaired, leading to toxicity.
- High folic acid doses: While folic acid supplementation is generally safe, high doses (above 1 mg daily) can mask vitamin B12 deficiency symptoms, leading to irreversible nerve damage if untreated.

Folic Acid + Zinc Side Effects - What to Expect

Folic acid and zinc supplements are generally well tolerated, but side effects can occur, particularly when taken in high doses:
- Gastrointestinal distress: Zinc may cause nausea, vomiting, abdominal pain, and diarrhea, especially when taken on an empty stomach. To reduce these side effects, it is best to take zinc with food.
- Copper deficiency: Long-term use of high doses of zinc (above 40 mg per day) can lead to copper deficiency, which can cause symptoms such as anemia, fatigue, and impaired immune function.
- Folic acid toxicity: High doses of folic acid (above 1 mg) can lead to masking the symptoms of vitamin B12 deficiency, potentially causing irreversible nerve damage if not treated. It may also cause gastrointestinal issues such as bloating and gas.
- Nausea and vomiting: Both high doses of zinc and folic acid may cause nausea, vomiting, and loss of appetite, particularly in sensitive individuals.
- Metallic taste: Some individuals may experience a metallic taste in the mouth when taking zinc supplements, especially at higher doses.

Folic Acid + Zinc Pregnancy Category ID - Safety Information

1

Folic Acid + Zinc Mode of Action - How It Works

Folic acid and zinc exert their effects in different but complementary ways:
- Folic acid: Folic acid, also known as Vitamin B9, is converted into tetrahydrofolate (THF), which is essential for DNA and RNA synthesis. This process is crucial for cell division, tissue growth, and the production of red blood cells. It also plays a significant role in the metabolism of homocysteine, an amino acid linked to cardiovascular disease when present in excess.
- Zinc: Zinc is a cofactor for over 300 enzymes involved in protein synthesis, cell division, and wound healing. It also plays a critical role in immune function, DNA synthesis, and cell growth. Zinc helps maintain healthy skin and contributes to the proper functioning of the senses of taste and smell. It is essential for the synthesis of proteins and collagen, supporting wound healing and tissue repair.

Folic Acid + Zinc Drug Interactions - What to Avoid

The combination of folic acid and zinc may interact with various substances, including medications, foods, and other nutrients:
- Medications: Zinc supplementation can interfere with the absorption of certain antibiotics (e.g., tetracyclines, quinolones), and high doses of zinc may interact with medications used to treat diabetes, such as insulin. Folic acid may also interact with certain chemotherapy drugs, reducing their effectiveness.
- Iron supplements: Zinc and iron compete for absorption in the intestines, so it is recommended to take them at different times of the day to maximize their absorption.
- Copper: Chronic high-dose zinc supplementation can lead to copper deficiency, as both minerals share similar absorption pathways. It is important to monitor copper levels if using long-term zinc supplementation.
- Vitamin C: Vitamin C may enhance zinc absorption, so a supplement containing both could improve zinc bioavailability. However, excessive vitamin C could interfere with zinc metabolism when taken in large doses.
- Alcohol: Chronic alcohol consumption can interfere with zinc absorption and increase folate metabolism, leading to deficiencies in both. Avoid excessive alcohol intake while taking zinc and folic acid supplements.

Folic Acid + Zinc Adult Dose - Recommended Dosage

The recommended dose of folic acid and zinc varies based on age, sex, and specific health conditions:
- Folic acid: For general health, the recommended daily dose is 400 mcg for adults. Pregnant women typically require 600-800 mcg daily to prevent neural tube defects in the developing fetus.
- Zinc: The recommended daily intake for zinc is 11 mg for adult men and 8 mg for adult women. In cases of deficiency or for specific health concerns, the dose may be higher, but long-term use of more than 40 mg per day should be avoided without medical supervision due to the risk of toxicity.

Folic Acid + Zinc Child Dose - Dosage for Children

For children, the recommended doses of folic acid and zinc vary by age:
- Folic acid: Children aged 1-3 years should receive 150 mcg, 4-8 years 200 mcg, and children aged 9-13 years 300 mcg per day. For children older than 14 years, the adult dose of 400 mcg is typically recommended.
- Zinc: The recommended zinc intake for children is 2-5 mg for infants, 5 mg for children 1-3 years, 8 mg for children 4-8 years, and 11 mg for children 9-13 years. Adolescents aged 14-18 years may need 11-12 mg daily.

Folic Acid + Zinc Renal Dose - Dosage for Kidney Conditions

In patients with kidney disease or renal impairment, both folic acid and zinc should be used with caution:
- Folic acid: No significant dose adjustment is typically required for renal impairment, as folic acid is water-soluble and excreted via the kidneys. However, in cases of severe renal failure, healthcare providers may monitor serum levels.
- Zinc: Zinc supplementation should be carefully monitored in individuals with renal disease, as impaired renal function can lead to zinc accumulation and potential toxicity. Lower doses may be recommended for individuals with chronic kidney disease.

  • Specific mineral & vitamin combined preparations -
  • banner

    Contact Us / Report Error

    Please contact us for any inquiries or report any errors.

    Or U can Send Us Email: [email protected]

    Available as

    Not available in a medicine form yet