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This medicine contains important and useful components, as it consists of
Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes Eye prep is available in the market in concentration.
Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes Eye prep
Before using Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation, patients must consult their healthcare provider to ensure its suitability for their specific condition. Precautions include:
- Allergic Reactions: Patients with known hypersensitivity to Vitamin A palmitate, Carbomer 980, Polyvidone, electrolytes, or any other components of the formulation should avoid using this medication.
- Contact Lenses: Remove contact lenses before applying the eye preparation. Reinsert lenses only after 15 minutes to avoid irritation or absorption of the preservatives.
- Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding, as systemic absorption of Vitamin A can affect fetal development or pass into breast milk.
- Eye Infections: Do not use if there is an active eye infection, as it may exacerbate the condition.
- Driving and Operating Machinery: Temporary blurred vision may occur after application. Avoid activities requiring clear vision until eyesight returns to normal.
- Pediatric and Geriatric Use: Use with caution in children and elderly patients, as safety and efficacy may vary.
Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation is primarily indicated for:
- Dry Eye Syndrome: It is used to relieve symptoms of dry eyes, such as irritation, burning, and discomfort, by providing lubrication and stabilizing the tear film.
- Vitamin A Deficiency: It helps treat ocular surface disorders caused by Vitamin A deficiency, which can lead to night blindness, xerophthalmia, and corneal ulcers.
- Post-Surgical Care: It may be prescribed after ocular surgeries to promote healing and maintain ocular surface integrity.
- Environmental Irritants: Provides relief from eye discomfort caused by environmental factors like smoke, wind, or prolonged screen use.
Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation is contraindicated in the following situations:
- Hypersensitivity: Patients with a known allergy to Vitamin A palmitate, Carbomer 980, Polyvidone, electrolytes, or any excipients in the formulation.
- Active Eye Infections: Avoid use in cases of bacterial, viral, or fungal eye infections, as it may worsen the condition.
- Severe Ocular Surface Damage: Not recommended for severe corneal ulcers or injuries without medical supervision.
- Systemic Vitamin A Toxicity: Patients with hypervitaminosis A should avoid this medication to prevent exacerbation of symptoms.
Common and severe side effects of Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation include:
- Common Side Effects:
- Temporary blurred vision
- Mild eye irritation or burning
- Redness or itching of the eyes
- Watery eyes
- Severe Side Effects (require immediate medical attention):
- Severe eye pain or swelling
- Vision changes or loss
- Signs of allergic reaction (e.g., rash, itching, swelling of the face or throat)
- Persistent irritation or discomfort
Patients should discontinue use and consult their healthcare provider if severe side effects occur.
Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation works through the following mechanisms:
- Vitamin A Palmitate: Acts as a lubricant and promotes the regeneration of epithelial cells on the ocular surface. It helps maintain the integrity of the cornea and conjunctiva, reducing dryness and irritation.
- Carbomer 980: A mucoadhesive polymer that forms a protective gel-like layer on the eye surface, prolonging the retention time of the formulation and providing sustained lubrication.
- Polyvidone: Enhances the viscosity of the tear film, improving moisture retention and providing additional lubrication.
- Electrolytes: Help maintain the osmotic balance of the tear film, promoting a healthy ocular surface environment.
- Tear Film Stabilization: Enhances the stability of the tear film, reducing evaporation and improving moisture retention on the ocular surface.
Potential interactions of Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation include:
- Other Ocular Medications: Concurrent use with other eye drops or ointments may alter the absorption or efficacy of either product. Administer at least 15 minutes apart.
- Systemic Vitamin A Supplements: Combining with oral Vitamin A supplements may increase the risk of hypervitaminosis A, leading to toxicity symptoms like dizziness, nausea, and headaches.
- Retinoids: Topical or systemic retinoids (e.g., isotretinoin) may enhance the risk of Vitamin A toxicity.
- Herbal Products: Herbal supplements containing high doses of Vitamin A (e.g., cod liver oil) should be avoided to prevent excessive Vitamin A levels.
The recommended dosing for adults is as follows:
- Dry Eye Syndrome: Instill 1-2 drops into the affected eye(s) 3-4 times daily or as directed by a healthcare provider.
- Vitamin A Deficiency: Follow the prescribed dosage, typically 1-2 drops 2-3 times daily, depending on the severity of the deficiency.
- Post-Surgical Care: Use as directed by the ophthalmologist, usually 1-2 drops 2-4 times daily for a specified duration.
The safety and efficacy of Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation in pediatric patients have not been extensively studied. Use in children should be under the guidance of a healthcare provider, with dosing typically adjusted based on age, weight, and the severity of the condition. For example:
- Children (6-12 years): 1 drop in the affected eye(s) 2-3 times daily.
- Children (<6 years): Use only if prescribed by a pediatric ophthalmologist, with careful monitoring for adverse effects.
Always consult a healthcare provider before administering this medication to children.
No specific dosage adjustments are required for patients with renal impairment, as the systemic absorption of Vitamin A palmitate Carbomer 980 + Polyvidone + Electrolytes eye preparation is minimal. However, patients with severe renal impairment should consult their healthcare provider before use.