Calcium Acetate

Welcome to Dwaey, specifically on Calcium Acetate page.
This medicine contains important and useful components, as it consists of
Calcium Acetate is available in the market in concentration.

Generic Name of Calcium Acetate - Learn More

Calcium Acetate

Calcium Acetate Precaution - What You Need to Know

- Monitor calcium levels: Regular monitoring of calcium and phosphorus levels is essential, especially in patients with chronic kidney disease (CKD) or those on long-term calcium acetate therapy. Hypercalcemia may develop, causing serious complications such as kidney stones or cardiovascular issues.
- Renal function monitoring: Patients with impaired renal function should be closely monitored, as calcium acetate is eliminated via the kidneys. Dosage adjustments may be necessary to avoid toxicity.
- Hypercalcemia risk: Overuse of calcium acetate can lead to elevated calcium levels in the blood, which can cause symptoms like nausea, vomiting, and confusion.
- Drug interactions: Be aware of potential interactions with other medications such as thiazide diuretics, which may increase calcium levels, and phosphate binders, which may alter calcium absorption.
- Pregnancy and breastfeeding: Calcium acetate is generally considered safe during pregnancy and breastfeeding, but it should only be used when necessary, and the dosage should be carefully controlled.
- Cardiovascular disease: People with heart disease should use calcium acetate cautiously, as high calcium levels may affect heart rhythm and function.
- Gastrointestinal issues: Individuals with a history of gastrointestinal issues, such as peptic ulcers or bowel disease, should take calcium acetate with food to minimize gastrointestinal irritation.

Calcium Acetate Indication - Uses and Benefits

- Phosphate control in CKD: Calcium acetate is primarily used as a phosphate binder to reduce elevated phosphate levels in patients with chronic kidney disease (CKD). By binding phosphate in the gastrointestinal tract, it prevents the absorption of phosphate, reducing the risk of hyperphosphatemia and related complications.
- Hyperphosphatemia: Indicated in patients with elevated phosphate levels, commonly seen in CKD, particularly in those on dialysis.
- Osteomalacia and rickets: Calcium acetate may be used in patients with calcium deficiencies, such as those with osteomalacia or rickets, to improve bone mineralization.
- Calcium supplementation: As a source of calcium, it is used for patients requiring calcium supplementation, such as those with osteoporosis or hypocalcemia.

Calcium Acetate Contraindications - Important Warnings

- Hypercalcemia: Contraindicated in patients with elevated blood calcium levels (hypercalcemia), as calcium acetate can exacerbate this condition and increase the risk of kidney stones and cardiovascular complications.
- Calcium or vitamin D overdose: If a patient is already experiencing a calcium or vitamin D overdose, calcium acetate should not be used, as this may worsen the toxicity.
- Severe renal impairment: Contraindicated in patients with severe renal dysfunction, as impaired kidney function may hinder the elimination of calcium acetate, leading to toxicity.
- Hypercalciuria: Contraindicated in individuals with high calcium levels in their urine (hypercalciuria), as this increases the risk of kidney stones.
- Allergic reaction: Should not be used by individuals with a known allergy or hypersensitivity to calcium acetate or any other ingredients in the formulation.

Calcium Acetate Side Effects - What to Expect

- Hypercalcemia: The most common side effect, which can cause nausea, vomiting, constipation, abdominal pain, muscle weakness, confusion, and kidney stones.
- Gastrointestinal symptoms: Includes nausea, constipation, bloating, and abdominal discomfort. These symptoms are generally alleviated by taking the medication with food.
- Kidney stones: Prolonged use of calcium acetate may increase the risk of developing kidney stones, particularly in patients with pre-existing kidney disease or those with elevated calcium levels.
- Electrolyte imbalances: Elevated calcium levels may lead to imbalances in other electrolytes like magnesium or phosphorus, resulting in muscle cramps or weakness.
- Cardiovascular symptoms: High calcium levels may lead to arrhythmias or palpitations, especially in individuals with cardiovascular disease.
- Fatigue: Some patients may experience unusual fatigue or weakness when taking calcium acetate, particularly if calcium levels become elevated.
- Headache: Headaches may occur as a result of fluctuating calcium levels or dehydration.

Calcium Acetate Pregnancy Category ID - Safety Information

3

Calcium Acetate Mode of Action - How It Works

- Phosphate binding: Calcium acetate acts as a phosphate binder in the gastrointestinal tract, binding to phosphate in the food and preventing its absorption into the bloodstream. By reducing phosphate absorption, it helps to control elevated phosphate levels, which is a common problem in patients with chronic kidney disease (CKD).
- Calcium supplementation: Calcium acetate also acts as a calcium supplement, providing the body with a necessary mineral for bone health. It aids in the absorption of calcium in the intestine and supports bone mineralization.
- Bone mineralization: By regulating calcium and phosphate balance, calcium acetate helps maintain proper bone structure and function. It is particularly important in patients with conditions like osteoporosis or osteomalacia.

adult_dose
- Standard dose: The typical adult dose of calcium acetate for hyperphosphatemia in CKD is 1-2 tablets (667 mg to 1334 mg) taken 2-3 times daily with meals.
- Adjustments: The dose should be adjusted based on the patient’s phosphate levels and clinical condition. Dosage can be increased or decreased to maintain phosphate control without causing hypercalcemia.
- Administration: Take calcium acetate with food to enhance phosphate binding and reduce the risk of gastrointestinal discomfort.

renal_dose
- Renal impairment: In patients with renal impairment, calcium acetate should be used cautiously, with regular monitoring of calcium and phosphate levels. The dosage may need to be reduced in patients with moderate to severe kidney disease to avoid the risk of hypercalcemia.
- Dialysis patients: For patients on dialysis, calcium acetate is commonly used to control phosphate levels, but it must be adjusted based on lab results. Doses may be lower in these patients due to their altered metabolism.

child_dose
- Use in children: Calcium acetate is typically not recommended for children under the age of 12 unless specifically prescribed by a pediatric healthcare provider. Dosing for children, if required, is based on body weight and phosphate levels, and should be carefully monitored.
- Adjustment: Pediatric doses must be adjusted individually, especially in cases of chronic kidney disease or other conditions requiring phosphate control. Regular monitoring of calcium and phosphate levels is essential in children.

Calcium Acetate Drug Interactions - What to Avoid

- Thiazide diuretics: Thiazide diuretics, such as hydrochlorothiazide, may increase calcium levels in the blood. When used in conjunction with calcium acetate, there is a higher risk of developing hypercalcemia. Monitoring calcium levels is essential.
- Phosphate binders: Other phosphate binders, such as sevelamer or lanthanum carbonate, may interfere with calcium acetate’s ability to bind phosphate. These drugs should not be taken at the same time.
- Iron supplements: Calcium acetate may reduce the absorption of iron supplements if taken concurrently. These should be spaced apart to maximize absorption of both calcium and iron.
- Antacids: Calcium acetate may interact with calcium-containing antacids, increasing the risk of elevated calcium levels and the potential for hypercalcemia.
- Corticosteroids: Long-term use of corticosteroids can reduce calcium absorption, potentially interfering with the effectiveness of calcium acetate supplementation.
- Tetracycline antibiotics: Calcium acetate may reduce the absorption of tetracycline antibiotics like doxycycline and tetracycline. These medications should be taken at least 2 hours apart.