Alfacort Cream

What is Alfacort

ALFACORT Cream is a topical corticosteroid preparation containing the active ingredient Hydrocortisone. It is designed to help reduce inflammation, itching, redness, and discomfort associated with a variety of dermatologic conditions. The 30 g collapsible tube format allows for convenient use over a slightly larger or recurrently affected area.

• Generic Name: Hydrocortisone
• Formulation: Cream (emulsion)
• Strength: Usually 1 % w/w
• Package Size: 30 g collapsible tube
• Drug Class: Mild topical corticosteroid

This formulation is indicated for inflammatory and pruritic skin conditions such as:

• Atopic dermatitis (eczema)
• Contact dermatitis (allergic and irritant)
• Seborrheic dermatitis
• Insect bites, stings, and urticaria
• Mild plaque psoriasis (localized lesions)
• Pruritus from various causes

ALFACORT Cream relieves symptoms but does not cure underlying causes. Its mild potency makes it suitable for facial use, flexures (skin folds), or sensitive areas—always under medical guidance.

How to use Alfacort

Ensuring correct method and frequency of application maximizes efficacy while minimizing adverse effects:

• Preparation Before Use:
  • Wash hands thoroughly and cleanse the affected area with mild soap and water.
  • Pat dry with a soft towel to avoid irritation.
• Application Steps:
  • Dispense a thin layer of cream (approximately fingertip unit – FTU) onto the fingertip.
  • Gently smear over the affected area until no longer visible.
  • Wash hands after application (unless treating the hands).
• Frequency: Typically applied 1–2 times daily or as directed by a healthcare provider.
• Duration: Generally limit use to 7–14 days. Seek medical advice if symptoms persist beyond that or if infections develop.
• Special Precautions:
  • Avoid use on broken or infected skin without medical approval.
  • Avoid contact with eyes, eyelids, mouth, or mucous membranes.
  • Avoid occlusive dressings unless specifically prescribed.

Consistency is key—apply at similar times daily, gently but thoroughly. Do not skip doses or over-apply hoping to accelerate healing, as that may increase adverse effects.

Mode of Action Alfacort

Hydrocortisone in ALFACORT Cream is a synthetic glucocorticoid that mimics the anti-inflammatory and immunosuppressive actions of natural cortisol, acting topically to alleviate skin symptoms.

• Anti-inflammatory Effects:
  • Reduces release of inflammatory mediators (prostaglandins, leukotrienes).
  • Inhibits enzyme phospholipase A2, preventing arachidonic acid formation.
• Immunosuppressive Actions:
  • Suppresses immune cell migration (e.g., lymphocytes, macrophages) into inflamed tissue.
  • Reduces release of cytokines involved in inflammation.
• Vasoconstrictive Impact: Constricts small blood vessels, reducing redness and edema.

Upon topical application, the cream penetrates the epidermis, binds to cellular glucocorticoid receptors, and modulates gene transcription—downregulating pro-inflammatory factors and upregulating anti-inflammatory proteins. The cream base enhances hydration and penetration, ensuring localized action with minimal systemic absorption when used properly.

Alfacort Interactions Alfacort

Though systemic interactions are minimal with topical hydrocortisone, co-use with other products or medications can influence effectiveness or risk local adverse reactions.

• Topical Antimicrobials (antifungals, antibacterials): Use caution—hydrocortisone may mask infections or reduce immune response needed to clear them.
• Other topical corticosteroids or immunomodulators: Increased risk of skin thinning or systemic absorption if used over the same area.
• Topical irritants (e.g., keratolytics, retinoids): May worsen skin irritation or increase absorption of hydrocortisone.
• Skin tests or vaccines: Local steroids may interfere with immune response if applied at injection/test sites.

Always inform your physician of all topical and systemic therapies in use. Combining multiple corticosteroids may inadvertently increase potency and side effect risk.

Dosage of Alfacort

Dosage is primarily based on the treated area, condition severity, and patient age. Hydrocortisone is low potency, which allows for more flexibility, especially on sensitive skin.

• Adults: Thin layer applied 1–2 times daily to affected area.
• Children: Use no more than once daily on limited areas; avoid prolonged usage due to increased systemic absorption risk.
• Fingertip Unit (FTU):
  • 1 FTU (≈0.5 g cream) covers two adult palms (~0.07 m²).
  • Adjust amount as needed—avoid excess.
• Maximum Duration: Generally 7–14 days. Longer use requires medical reassessment and possible treatment rotation.
• Repeat Courses: Allow skin rest periods of at least 1 week between courses if extended control is needed.

The smallest effective dose for the shortest time is key to safe use. Monitor response and adjust under medical guidance.

Possible side effects of Alfacort

Although well tolerated with short-term use, topical hydrocortisone may lead to both local and rare systemic side effects, particularly with misuse or prolonged application.

• Local Reactions:
  • Skin thinning (atrophy) and fragility
  • Stretch marks (striae)
  • Telangiectasias (visible capillaries)
  • Burning, stinging, or pruritus at application site
  • Folliculitis, acneiform eruptions
• Allergic Responses:
  • Contact dermatitis, rash
  • Swelling or blistering in extreme cases
• Systemic Effects (uncommon but significant):
  • HPA-axis suppression, especially in children or if used long-term
  • Increased intraocular pressure if used near eyelids
  • Cushingoid features (with extensive or occluded use)

If severe or protracted side effects occur, discontinue use and consult a healthcare professional for guidance.

Alfacort Contraindications Alfacort

Use of ALFACORT Cream is contraindicated in certain situations to avoid exacerbation or complications.

• Hypersensitivity to hydrocortisone or cream components
• Untreated skin infections:
  • Bacterial (e.g., impetigo)
  • Fungal (e.g., candidiasis, dermatophyte infections)
  • Viral (e.g., herpes simplex, varicella)
• Skin conditions worsened by corticosteroids:
  • Rosacea
  • Perioral dermatitis
  • Acne vulgaris
• Application near eyes: May increase risk of glaucoma or cataracts without supervision
• Infants/diaper area: Avoid unless prescribed for specific severe conditions

Consult a healthcare provider if there is uncertainty—proper diagnosis and treatment customization are essential.

Storage of Alfacort

Proper storage preserves effectiveness, safety, and user compliance.

• Temperature: Store below 25 °C (77 °F); avoid freezing.
• Protection: Keep away from sunlight and moisture.
• Packaging: Keep in the original tube with cap tightly closed.
• Child Safety: Keep out of reach and sight of children.
• Expiration: Do not use beyond the printed expiry date.

Dispose of used or expired cream following local pharmaceutical waste guidelines. Avoid flushing down drains or throwing in general refuse, if unsuitable.