ALFACORT Cream

What is ALFACORT

ALFACORT Cream is a topical corticosteroid medication that contains Hydrocortisone as its active ingredient. It is used to relieve inflammation, itching, redness, and swelling associated with a variety of skin conditions. These include eczema, dermatitis, insect bites, allergic reactions, and rashes.

• Generic Name: Hydrocortisone
• Form: Topical cream
• Strength: Typically 1% w/w Hydrocortisone (check product label)
• Packaging: 15g tube
• Therapeutic Class: Mild corticosteroid

ALFACORT works by mimicking the effects of natural corticosteroids produced by the adrenal glands, thereby reducing the body’s inflammatory response. It is typically prescribed for short-term use to control flare-ups of inflammatory skin conditions.

This cream is suitable for mild conditions and can be used on sensitive skin areas, including the face, under close medical supervision. However, it is not a cure but a symptomatic treatment.

How to use ALFACORT

Proper application of ALFACORT Cream ensures maximum effectiveness and minimizes side effects. It is intended for external use only.

• Step-by-Step Application:
  • Wash and dry your hands before and after applying the cream.
  • Clean and gently dry the affected area.
  • Apply a thin layer of ALFACORT cream to the affected skin area.
  • Gently rub it in using circular motions until fully absorbed.
• Frequency: Usually applied 1–2 times daily or as directed by a physician.
• Duration: Use should be limited to a few days to a week. Prolonged use increases the risk of side effects.
• Avoid:
  • Using under occlusive dressings unless instructed.
  • Contact with eyes, mouth, or open wounds.
  • Using on infected, broken, or acne-prone skin unless prescribed.

Do not abruptly discontinue use if you have been using it for extended periods; tapering may be recommended. Always follow your healthcare provider’s guidance for best outcomes.

Mode of Action ALFACORT

Hydrocortisone, the active ingredient in ALFACORT Cream, is a synthetic corticosteroid that mimics cortisol, a hormone naturally produced by the adrenal glands. It exerts anti-inflammatory, anti-pruritic, and vasoconstrictive properties when applied topically.

• Anti-Inflammatory Action: Reduces the production of inflammatory mediators such as prostaglandins and leukotrienes.
• Immune Suppression: Suppresses local immune responses that cause swelling, redness, and itching in skin disorders.
• Vasoconstriction: Narrows blood vessels, decreasing fluid leakage and skin swelling.

When applied to the skin, hydrocortisone penetrates the outer layers (epidermis) and binds to intracellular glucocorticoid receptors. This binding alters the transcription of inflammatory genes and reduces the synthesis of pro-inflammatory cytokines.

The localized application ensures a targeted effect with minimal systemic absorption, especially when used as directed. However, systemic effects can occur if used on large surface areas or under occlusion for prolonged periods.

ALFACORT Interactions ALFACORT

Topical Hydrocortisone generally has fewer drug interactions compared to systemic corticosteroids, but interactions may still occur, especially when applied over large areas or used with other topical medications.

• Topical Antifungals or Antibacterials: Using with hydrocortisone may reduce their efficacy if the underlying infection is not adequately treated.
• Vaccines: Topical steroids may slightly suppress local immune response; avoid use before live-attenuated skin tests.
• Other Topical Products: Simultaneous application with other creams or ointments may affect absorption or increase local irritation. Apply each product at different times if both are prescribed.
• Systemic Corticosteroids: Using both systemic and topical corticosteroids may increase the risk of systemic side effects such as adrenal suppression.

Always inform your healthcare provider about all other treatments you are using, including over-the-counter medications, herbal supplements, and skin products.

Dosage of ALFACORT

The dosage of ALFACORT Cream should be tailored to the severity of the condition and the treatment area. It is usually measured in fingertip units (FTUs) for accuracy.

• Standard Adult Dosage: Apply a thin layer to the affected area 1–2 times daily.
• Pediatric Dosage: Use sparingly and under supervision; children are more prone to systemic absorption and side effects.
• Fingertip Unit Guide:
  • 1 FTU ≈ 0.5g of cream – enough to cover an area of two adult palms.
  • Use 1–2 FTUs for arms or legs, and less for smaller areas like the face.
• Maximum Duration: Usually no longer than 7 days unless advised by a physician.

If symptoms persist or worsen, consult a healthcare provider for reassessment. Do not use more frequently or in larger quantities than prescribed, as this can increase the risk of adverse effects.

Possible side effects of ALFACORT

While ALFACORT Cream is generally well tolerated when used short-term and correctly, prolonged or inappropriate use can lead to both local and systemic side effects.

• Common Local Side Effects:
  • Skin thinning (atrophy)
  • Burning or stinging sensation
  • Dryness or irritation
  • Redness (erythema)
• Less Common Effects:
  • Stretch marks (striae)
  • Perioral dermatitis
  • Contact dermatitis (allergic reaction)
  • Folliculitis (inflammation of hair follicles)
• Systemic Effects (rare but serious):
  • Adrenal suppression, especially in children or with prolonged use
  • Delayed wound healing
  • Increased risk of secondary infections

Discontinue use and consult a healthcare provider if any unusual or severe reactions occur, especially signs of skin infection or hypersensitivity.

ALFACORT Contraindications ALFACORT

ALFACORT Cream should not be used in certain conditions due to the risk of worsening symptoms or inducing complications.

• Hypersensitivity: Known allergy to Hydrocortisone or any excipients in the cream formulation.
• Untreated Skin Infections: Do not use on bacterial, fungal, or viral infections unless properly treated with antimicrobials.
• Rosacea: Can worsen inflammation and flushing.
• Acne Vulgaris: May aggravate acne lesions when applied to the face.
• Perioral Dermatitis: Use may exacerbate this condition.

Use in children should be limited and supervised, as they are more susceptible to systemic absorption and suppression of the hypothalamic-pituitary-adrenal (HPA) axis.

Storage of ALFACORT

Proper storage ensures the stability and effectiveness of the medication over its shelf life.

• Storage Temperature: Store below 25°C (77°F); do not freeze.
• Keep Out of Reach of Children: Prevent accidental ingestion or misuse.
• Container: Keep in the original tube with the cap tightly closed to prevent contamination.
• Do Not Use After Expiry Date: Check the date on the packaging before use.
• Avoid Exposure: Protect from direct sunlight and excessive heat.

Proper disposal of the cream should follow local regulations; do not flush into water systems or throw in general waste.