AIRTAL 100mg Tablets/Film-coated

What is AIRTAL 100mg

AIRTAL 100mg is a prescription medication that contains the active ingredient Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID). It is commonly used to manage pain and inflammation associated with various musculoskeletal and joint disorders.

• Generic Name: Aceclofenac
• Form: Film-coated tablets
• Strength: 100mg per tablet
• Packaging: 40 tablets (10s Blister x 4)

This medicine is primarily indicated for the symptomatic treatment of conditions such as:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Lower back pain and other inflammatory musculoskeletal disorders

It helps reduce swelling, stiffness, and pain, thereby improving the quality of life for patients with chronic inflammatory diseases.

How to use AIRTAL 100mg

AIRTAL 100mg should always be used as prescribed by a healthcare provider. Incorrect usage may reduce its effectiveness or increase the risk of side effects.

• Dosage: Typically, 100mg taken twice daily (morning and evening).
• Administration: Take the tablet orally with a glass of water.
• With food: It is advisable to take AIRTAL with or after meals to reduce the risk of gastrointestinal irritation.
• Do not:
  • Crush or chew the tablet
  • Exceed the prescribed dose
  • Take with alcohol or other NSAIDs unless advised

Missed Dose:

• If you miss a dose, take it as soon as you remember.
• If it's almost time for your next dose, skip the missed one—do not double the dose.

Important: Continue the medication for the full duration prescribed, even if symptoms improve early. Sudden discontinuation may result in symptom relapse.

Mode of Action AIRTAL 100mg

Aceclofenac, the active ingredient in AIRTAL 100mg, works by targeting the root cause of pain and inflammation in chronic joint and muscle conditions.

• NSAID Class: It belongs to the class of drugs known as non-steroidal anti-inflammatory drugs.
• Inhibits Cyclooxygenase (COX): Aceclofenac selectively inhibits the COX-2 enzyme more than COX-1.
• Reduces Prostaglandins: COX enzymes are responsible for converting arachidonic acid to prostaglandins, substances that mediate pain and inflammation. By reducing prostaglandin synthesis, Aceclofenac alleviates these symptoms.
• Dual Action: It exhibits both anti-inflammatory and analgesic properties, offering symptomatic relief in arthritis and other joint diseases.
• Onset: Therapeutic effects typically begin within 1–2 hours of oral administration.

Overall, Aceclofenac has been shown to be better tolerated gastrointestinally compared to some older NSAIDs like diclofenac or ibuprofen, while still providing effective pain control.

AIRTAL 100mg Interactions AIRTAL 100mg

Aceclofenac can interact with several other medications and substances, potentially affecting its efficacy or increasing the risk of adverse effects. Always inform your doctor of any medications or supplements you are taking.

• Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics): NSAIDs can reduce their effectiveness and may worsen kidney function.
• Anticoagulants (e.g., Warfarin): Increased risk of bleeding due to interference with platelet function.
• Other NSAIDs or corticosteroids: Increased risk of gastrointestinal bleeding or ulcers.
• SSRIs (e.g., fluoxetine, sertraline): Combined use can raise the risk of gastrointestinal bleeding.
• Antidiabetic agents: Possible alteration in blood glucose levels; monitor closely.
• Digoxin: Increased serum levels of digoxin may occur.
• Methotrexate: May elevate methotrexate levels and toxicity risk.

Alcohol: Should be avoided during treatment as it may increase the risk of gastric ulcers and liver toxicity.

Dosage of AIRTAL 100mg

The appropriate dose of AIRTAL (Aceclofenac) depends on the individual’s condition, age, and overall health. The following dosage guidelines are generally followed:

• Adults: 100mg twice daily (one tablet every 12 hours)
• Maximum daily dose: Do not exceed 200mg in a 24-hour period.
• Geriatric patients: Use with caution; start with the lowest effective dose and monitor for kidney function.
• Renal/hepatic impairment: Use with caution; dosage adjustment may be needed depending on severity.
• Children: Not recommended for use in children under 18 years unless specifically prescribed by a specialist.

Important considerations:

• Take with food or milk to minimize gastrointestinal side effects.
• Monitor long-term users for liver enzymes, kidney function, and blood pressure.
• Use the lowest effective dose for the shortest possible duration to reduce risk of complications.

Possible side effects of AIRTAL 100mg

Like all NSAIDs, Aceclofenac can cause side effects. These can vary from mild to serious and may require medical attention if persistent or severe.

Common side effects (may affect up to 1 in 10 people):

• Gastrointestinal discomfort (nausea, abdominal pain, indigestion)
• Diarrhea or constipation
• Dizziness or headache
• Skin rash or itching

Less common but serious side effects:

• Gastrointestinal bleeding or ulcers
• Elevation in liver enzymes
• Allergic reactions including skin rash, swelling, or breathing difficulty
• Increased blood pressure or worsening of pre-existing hypertension
• Kidney function impairment (especially with prolonged use)

Rare side effects:

• Hepatitis or liver toxicity
• Agranulocytosis (low white blood cell count)
• Stevens-Johnson syndrome (severe skin reaction)

If any of these serious symptoms occur, discontinue the medication and seek medical advice immediately.

AIRTAL 100mg Contraindications AIRTAL 100mg

AIRTAL 100mg is contraindicated in the following situations due to potential risks outweighing the benefits:

• Hypersensitivity: Known allergy to Aceclofenac or other NSAIDs (e.g., aspirin, ibuprofen)
• History of NSAID-induced asthma, urticaria, or allergic-type reactions
• Active or recurrent peptic ulcers or gastrointestinal bleeding
• Severe hepatic or renal impairment
• Severe heart failure
• Third trimester of pregnancy: NSAIDs can affect fetal circulation and kidney function
• Children under 18 years: Safety and efficacy not established

Always assess individual risk factors such as age, comorbid conditions, and concurrent medications before initiating Aceclofenac.

Storage of AIRTAL 100mg

Proper storage of AIRTAL ensures the medication remains safe and effective throughout its shelf life.

• Temperature: Store below 25°C (77°F), in a cool and dry place.
• Avoid humidity: Keep away from moisture and direct sunlight.
• Original packaging: Keep tablets in their original blister packaging until use to protect from light and air.
• Child safety: Store out of reach and sight of children.
• Disposal: Do not flush unused tablets. Dispose of via a pharmacy or appropriate medication take-back program.

Check expiry date before use. Do not use the medication if the packaging is damaged or the tablets show signs of deterioration (e.g., discoloration or crumbling).