ADOL 250mg/5ml Suspension

What is ADOL 250mg/5ml

ADOL 250mg/5ml Suspension is an oral liquid medication containing Paracetamol (also known as acetaminophen) as its active ingredient. Each 5ml of the suspension delivers 250mg of Paracetamol. It is commonly used to relieve mild to moderate pain and reduce fever in children. patient-info.co.uk Key Features: Active Ingredient: Paracetamol 250mg per 5ml. Formulation: Oral suspension, typically flavored to enhance palatability for children. Packaging: Available in a 135ml glass bottle. Therapeutic Uses: Relief of mild to moderate pain (e.g., headaches, toothaches, sore throats). Reduction of fever associated with colds, flu, and other infections. minclinic.eu Advantages: Suitable for children who have difficulty swallowing tablets. Provides precise dosing with the included measuring device. Rapid onset of action, typically within 30 to 60 minutes. Note: Always use under the guidance of a healthcare professional, especially in children under 6 years of age.

How to use ADOL 250mg/5ml

Administration Guidelines: Shake Well: Before each use, shake the bottle thoroughly for at least 10 seconds to ensure uniform distribution of the medication. Measuring the Dose: Use the provided measuring spoon or oral syringe for accurate dosing. Do not use household teaspoons, as they may not provide accurate measurements. Dosage Frequency: Administer every 4 to 6 hours as needed. Do not exceed 4 doses within a 24-hour period. Age Restrictions: Not recommended for children under 6 years of age unless directed by a healthcare provider. Duration of Use: Do not use for more than 3 consecutive days without consulting a doctor. medicines.org.uk +3 patient-info.co.uk +3 minclinic.eu +3 imedi.co.uk +2 patient-info.co.uk +2 medicines.org.uk +2 Important Precautions: Do not administer with other Paracetamol-containing products to avoid overdose. If a dose is missed, do not double the next dose; simply continue with the regular dosing schedule. In case of overdose, seek immediate medical attention, even if no symptoms are present, due to the risk of delayed liver damage.

Mode of Action ADOL 250mg/5ml

Paracetamol, the active ingredient in ADOL Suspension, is a widely used analgesic (pain reliever) and antipyretic (fever reducer). Mechanism of Action: Central Inhibition of Prostaglandin Synthesis: Paracetamol inhibits the enzyme cyclooxygenase (COX), particularly COX-3 in the central nervous system, leading to reduced synthesis of prostaglandins that cause pain and fever. Antipyretic Effect: It acts on the hypothalamic heat-regulating center to promote vasodilation and sweating, thereby reducing fever. Lack of Anti-inflammatory Activity: Unlike non-steroidal anti-inflammatory drugs (NSAIDs), Paracetamol has minimal anti-inflammatory effects, making it gentler on the stomach lining. Pharmacokinetics: Onset of Action: Typically within 30 to 60 minutes after oral administration. Duration of Action: Approximately 4 to 6 hours. Metabolism: Primarily metabolized in the liver and excreted by the kidneys. Clinical Implications: Effective for managing mild to moderate pain and fever in children. Suitable for patients who cannot tolerate NSAIDs. Low risk of gastrointestinal side effects when used as directed.

ADOL 250mg/5ml Interactions ADOL 250mg/5ml

While Paracetamol is generally safe, it can interact with certain medications, potentially altering its effectiveness or increasing the risk of adverse effects. Notable Drug Interactions: Enzyme-Inducing Drugs: Medications such as carbamazepine, phenytoin, and rifampicin can increase the metabolism of Paracetamol, reducing its efficacy and potentially increasing liver toxicity. Warfarin and Other Anticoagulants: Regular use of Paracetamol may enhance the anticoagulant effect, increasing the risk of bleeding. Occasional use has minimal effect. Metoclopramide and Domperidone: These drugs can increase the rate of Paracetamol absorption, leading to a quicker onset of action. Cholestyramine: May reduce the absorption of Paracetamol if taken within an hour of administration. Alcohol: Chronic alcohol consumption can increase the risk of Paracetamol-induced liver toxicity. Flucloxacillin: Concurrent use with Paracetamol has been associated with high anion gap metabolic acidosis, especially in patients with risk factors. medicines.org.uk +2 medicines.org.uk +2 medicines.org.uk +2 Recommendations: Always inform your healthcare provider about all medications your child is taking. Avoid combining ADOL with other Paracetamol-containing products. Monitor for signs of bleeding if your child is on anticoagulant therapy.

Dosage of ADOL 250mg/5ml

The appropriate dosage of ADOL Suspension depends on the child's age and weight. It is crucial to adhere to dosing guidelines to avoid the risk of overdose. Recommended Dosage: Age Group Dosage Frequency 6–8 years 5ml Up to 4 times in 24 hours 8–10 years 7.5ml (5ml + 2.5ml) Up to 4 times in 24 hours 10–12 years 10ml (5ml + 5ml) Up to 4 times in 24 hours 12–16 years 10–15ml Up to 4 times in 24 hours Adults (>16 yrs) 10–20ml Up to 4 times in 24 hours Key Points: Leave at least 4 hours between doses. Do not exceed 4 doses in any 24-hour period. Do not use for more than 3 consecutive days without consulting a doctor. Use the provided measuring device for accurate dosing. medcare-healthclinic.com +5 minclinic.eu +5 patient-info.co.uk +5 medicines.org.uk +2 patient-info.co.uk +2 minclinic.eu +2 patient-info.co.uk Note: In case of overdose, seek immediate medical attention, even if no symptoms are present, due to the risk of delayed liver damage.

Possible side effects of ADOL 250mg/5ml

ADOL Suspension is generally well-tolerated when used as directed. However, some individuals may experience side effects. Common Side Effects: Nausea or mild gastrointestinal discomfort. Drowsiness or tiredness (rare). Serious Side Effects (Seek Immediate Medical Attention): Allergic reactions: skin rash, itching, swelling of the face/lips, difficulty breathing. Liver damage: yellowing of the skin or eyes (jaundice), dark urine, abdominal pain. Blood disorders: unusual bruising or bleeding, sore throat, fever. Severe skin reactions: redness, blistering, peeling. patient-info.co.uk Overdose Symptoms: Nausea, vomiting, loss of appetite. Abdominal pain, especially in the upper right side. Confusion, unusual tiredness. Note: If any of these symptoms occur, discontinue use and seek medical attention immediately.

ADOL 250mg/5ml Contraindications ADOL 250mg/5ml

ADOL Suspension should not be used in certain individuals due to potential risks. Contraindications: Hypersensitivity: Known allergy to Paracetamol or any of the excipients in the suspension. Severe Liver Impairment: Paracetamol is metabolized by the liver; impaired function can lead to toxicity. Severe Renal Impairment: Use with caution; dosage adjustments may be necessary. Hereditary Fructose Intolerance: The suspension contains sorbitol, which can cause adverse effects in these individuals. imedi.co.uk Precautions: Avoid concurrent use with other Paracetamol-containing products. Sources

Storage of ADOL 250mg/5ml

Proper storage ensures the safety and effectiveness of the medication throughout its shelf life. Storage Conditions: Temperature: Store below 25°C (77°F). Keep out of direct sunlight and away from heat or moisture. Do not freeze. Freezing may alter the consistency and effectiveness of the suspension. Container Guidelines: Keep the bottle tightly closed when not in use to prevent contamination. Use only the original glass bottle with its cap securely fastened. Always shake well before use to ensure uniform dispersion of the medication. Keep Out of Reach of Children: Store in a safe location to prevent accidental ingestion by children. Shelf Life: Check the expiry date on the label before each use. Discard any remaining suspension 6 months after opening, or as instructed by the manufacturer or pharmacist.