ADOL 120mg/5ml Syrup

What is ADOL 120mg/5ml

ADOL 120mg/5ml Syrup is an oral liquid medication that contains Paracetamol (also known as Acetaminophen) as its active ingredient. It is primarily used for its analgesic (pain-relieving) and antipyretic (fever-reducing) properties.

• Formulation: Each 5ml of syrup contains 120mg of Paracetamol, suitable for children and adults who prefer liquid medication over tablets.
• Uses:
  • Relieves mild to moderate pain such as headache, toothache, muscle aches, or sore throat.
  • Reduces fever caused by infections or vaccinations.
  • Can be part of treatment plans for common cold or flu symptoms.
• Age group suitability: Primarily formulated for pediatric use, but may be used in adults who require or prefer a syrup formulation.
• Availability: Over-the-counter (OTC) medication in most countries.

ADOL Syrup is widely trusted for its safety profile and is commonly recommended by pediatricians for fever and mild pain relief in children. It should always be administered in the proper dosage according to the patient’s age and weight.

How to use ADOL 120mg/5ml

Proper administration of ADOL Syrup ensures optimal therapeutic effect while minimizing the risk of side effects or overdose.

• Before use: Shake the bottle well to ensure uniform distribution of the medication.
• Dosage measurement: Use a proper measuring spoon or oral syringe. Avoid household teaspoons for accurate dosing.
• Administration guidelines:
  • Can be taken with or without food.
  • If your child vomits within 30 minutes of taking a dose, consult a healthcare provider. A repeat dose may be necessary.
• Recommended frequency: Every 4 to 6 hours as needed. Do not exceed 4 doses in 24 hours.
• Hydration: Ensure adequate fluid intake when using Paracetamol for fever management.

Always follow the instructions provided by your doctor or those on the product label. If symptoms persist for more than 3 days, consult a healthcare professional. Never self-adjust the dose without professional guidance.

Mode of Action ADOL 120mg/5ml

Paracetamol, the active ingredient in ADOL Syrup, works through both central and peripheral mechanisms to relieve pain and reduce fever.

• Analgesic effect (Pain relief):
  • Inhibits the cyclooxygenase (COX) enzymes in the brain, reducing the synthesis of prostaglandins—chemicals that mediate pain.
  • Unlike NSAIDs, Paracetamol does not have significant anti-inflammatory effects.
• Antipyretic effect (Fever reduction):
  • Acts on the hypothalamic heat-regulating center to produce peripheral vasodilation and increased heat dissipation.
  • Helps restore body temperature to normal without affecting the body’s normal immune response.
• Onset of action:
  • Begins to work within 30 minutes after oral administration.
  • Peak effect usually observed within 1–2 hours.

Due to its favorable safety profile, Paracetamol is suitable for all age groups, including infants, when used as recommended. However, caution is required in patients with liver disease or chronic alcohol use.

ADOL 120mg/5ml Interactions ADOL 120mg/5ml

Although Paracetamol is generally safe, interactions with other substances can alter its effectiveness or increase the risk of side effects.

• Alcohol:
  • Chronic alcohol consumption increases the risk of liver toxicity from Paracetamol.
• Enzyme-inducing drugs:
  • Rifampicin, phenytoin, carbamazepine may increase the metabolism of Paracetamol, raising the risk of hepatotoxicity.
• Warfarin and other anticoagulants:
  • Frequent use may increase the risk of bleeding due to enhanced anticoagulant effects.
• Other Paracetamol-containing products:
  • Taking multiple products with Paracetamol can lead to accidental overdose.

To avoid harmful interactions, always inform your healthcare provider about all the medications, supplements, and herbal products you or your child are taking.

Dosage of ADOL 120mg/5ml

Accurate dosing of ADOL Syrup is crucial for effectiveness and safety, especially in children. Dosage is typically based on the child's weight and age.

• Infants (2–3 months): Only under medical supervision. Generally 2.5ml if required for fever after immunization.
• 3–6 months: 2.5ml every 4–6 hours (maximum 4 doses in 24 hours).
• 6–24 months: 5ml every 4–6 hours.
• 2–4 years: 7.5ml every 4–6 hours.
• 4–6 years: 10ml every 4–6 hours.

Important Dosage Guidelines:

• Do not exceed a total daily dose of 60mg/kg body weight.
• Do not administer more than 4 doses in 24 hours.
• Use the measuring device provided to ensure precision.

If a dose is missed, it can be given when remembered, but ensure at least a 4-hour gap before the next dose. Overdose can lead to serious liver damage and should be treated as a medical emergency.

Possible side effects of ADOL 120mg/5ml

Paracetamol is usually well-tolerated, but like any medication, ADOL Syrup may cause side effects in some individuals.

• Common (usually mild):
  • Nausea or vomiting
  • Mild abdominal discomfort
  • Drowsiness (rare)
• Rare but serious:
  • Allergic reactions (rash, itching, swelling of face or throat)
  • Liver toxicity, especially with overdose or in patients with liver disease
  • Thrombocytopenia (low platelet count)
• Signs of overdose:
  • Nausea, vomiting
  • Loss of appetite
  • Confusion, jaundice, or abdominal pain (late signs of liver damage)

Contact a healthcare provider if any unusual or persistent symptoms occur. In case of suspected overdose, seek emergency medical attention immediately.

ADOL 120mg/5ml Contraindications ADOL 120mg/5ml

ADOL Syrup is contraindicated in specific conditions where the use of Paracetamol could pose a risk to the patient.

• Known hypersensitivity:
  • Allergy to Paracetamol or any excipient in the syrup formulation.
• Severe liver impairment:
  • Paracetamol is metabolized in the liver; severe dysfunction may increase the risk of toxicity.
• Severe renal impairment:
  • Accumulation of Paracetamol or its metabolites can occur.
• Concurrent use of hepatotoxic drugs:
  • Using Paracetamol with drugs that stress the liver increases risk of hepatic injury.

Use with caution in patients with chronic alcohol use, dehydration, or poor nutritional status. Always consult with a doctor before giving the medication to infants under 2 months of age.

Storage of ADOL 120mg/5ml

Proper storage ensures the stability and effectiveness of the medication throughout its shelf life.

• Storage temperature:
  • Store below 25°C (77°F). Do not refrigerate or freeze.
• Packaging:
  • Keep in the original amber bottle to protect from light.
• Child safety:
  • Keep out of reach of children to avoid accidental ingestion.
• Expiry:
  • Do not use after the expiry date mentioned on the packaging.
  • Discard any remaining syrup one month after opening the bottle, unless advised otherwise by a pharmacist.

Ensure the cap is tightly closed after each use. Do not use if there is a change in color, consistency, or smell of the syrup.