ADOL 120mg/5ml Syrup

What is ADOL 120mg/5ml

ADOL 120mg/5ml Syrup is a liquid oral formulation that contains Paracetamol (also known as Acetaminophen) as the active ingredient. It is commonly used to relieve mild to moderate pain and to reduce fever in both children and adults.

• Each 5ml of the syrup contains 120mg of Paracetamol.
• Available in a 60ml bottle, making it suitable for short-term pediatric use.
• Typically prescribed for fever associated with cold, flu, teething, or post-vaccination reactions in children.
• Also effective in relieving mild pain such as headaches, sore throat, muscle aches, or earache.

This medication is generally well-tolerated and is considered safe when used at recommended doses. It is available over-the-counter but should be used under the guidance of a healthcare professional, especially in pediatric populations.

How to use ADOL 120mg/5ml

Proper use of ADOL 120mg/5ml Syrup ensures effective relief while minimizing the risk of side effects or overdose.

• Shake the bottle well before each use to ensure even distribution of the medication.
• Always use the measuring spoon or cup provided with the product for accurate dosing.
• Follow the dosage instructions provided by your physician or as indicated on the package insert.
• For children, dosage is typically based on body weight or age. Do not exceed the recommended dose.
• Administer orally with or without food. Taking it with food can help reduce the risk of stomach upset.
• Maintain a minimum of 4–6 hours between doses. Do not give more than 4 doses in 24 hours.

If symptoms persist beyond 3 days or worsen, consult a healthcare provider. Do not use in combination with other medications containing Paracetamol to avoid overdose.

Mode of Action ADOL 120mg/5ml

Paracetamol, the active ingredient in ADOL Syrup, works through central mechanisms in the brain to reduce pain and fever.

• Analgesic (pain-relieving) effect: Paracetamol inhibits cyclooxygenase (COX) enzymes in the central nervous system, particularly COX-2. This results in decreased synthesis of prostaglandins, chemicals responsible for pain perception.
• Antipyretic (fever-reducing) effect: It acts on the hypothalamic heat-regulating center to reduce elevated body temperature.
• Minimal anti-inflammatory action: Unlike NSAIDs, Paracetamol does not significantly reduce inflammation.
• Selective action: Its selectivity for the central nervous system rather than peripheral tissues reduces the risk of gastric irritation and bleeding, which are common with NSAIDs.

This makes ADOL syrup particularly suitable for children and individuals who are sensitive to non-steroidal anti-inflammatory drugs.

ADOL 120mg/5ml Interactions ADOL 120mg/5ml

While Paracetamol is generally safe, it may interact with other medications or substances. Here are some important drug interactions to consider:

• Warfarin and other anticoagulants: Prolonged use of Paracetamol may increase the risk of bleeding by enhancing the anticoagulant effect. Short-term use is generally safe.
• Enzyme inducers (e.g., Carbamazepine, Phenytoin, Rifampicin): These drugs increase the risk of liver toxicity by accelerating the metabolism of Paracetamol into its toxic metabolites.
• Alcohol: Chronic alcohol consumption may enhance hepatotoxicity, especially when combined with high doses of Paracetamol.
• Cholestyramine: May reduce the absorption of Paracetamol if administered closely in time.
• Metoclopramide and Domperidone: These drugs can increase the absorption rate of Paracetamol, leading to a faster onset of action.

Always inform your doctor or pharmacist about all medications, vitamins, or herbal supplements your child is taking to avoid potential interactions.

Dosage of ADOL 120mg/5ml

The dosage of ADOL Syrup should be individualized based on the child’s weight and age. Below is a general guideline:

• Infants (3–12 months): 2.5–5 ml every 4–6 hours as needed
• Children (1–5 years): 5–10 ml every 4–6 hours as needed
• Children (6–12 years): 10–20 ml every 4–6 hours as needed
• Maximum Daily Dose: Do not exceed 60mg/kg/day or 4 doses per 24 hours.

Important Dosage Tips:

• Always use the correct measuring device provided.
• Do not exceed recommended frequency or dose to avoid liver toxicity.
• In case of a missed dose, give it as soon as remembered unless it's close to the next dose.
• Consult a physician if fever or pain persists beyond 3 days.

Possible side effects of ADOL 120mg/5ml

ADOL Syrup is generally safe when used appropriately, but like all medications, it can cause side effects in some individuals.

• Common (usually mild and self-limiting):
  • Nausea
  • Vomiting
  • Mild stomach upset
• Rare but Serious:
  • Allergic reactions (rash, itching, swelling of face or throat)
  • Liver damage (especially in case of overdose or prolonged use)
  • Blood disorders (e.g., thrombocytopenia, leukopenia)
• Signs of overdose:
  • Nausea, vomiting, abdominal pain
  • Confusion or sleepiness
  • Yellowing of skin or eyes (jaundice)

If any of these symptoms occur, stop the medication immediately and seek medical attention.

ADOL 120mg/5ml Contraindications ADOL 120mg/5ml

ADOL Syrup should not be used in certain medical situations. Here are the contraindications:

• Hypersensitivity: Individuals with known allergy to Paracetamol or any of the syrup's components should avoid its use.
• Severe liver impairment: Due to its metabolism in the liver, Paracetamol is contraindicated in patients with severe hepatic insufficiency.
• Glucose-6-phosphate dehydrogenase (G6PD) deficiency: Use with caution; although rare, it may increase the risk of hemolysis.
• Alcoholism: Chronic alcohol abuse increases the risk of liver toxicity.

Always consult a doctor before using in children with underlying chronic conditions or those taking multiple medications.

Storage of ADOL 120mg/5ml

Proper storage of ADOL Syrup helps maintain its efficacy and safety.

• Storage temperature: Store below 25°C (77°F) in a dry place away from direct sunlight and moisture.
• Do not refrigerate or freeze the syrup unless specified by the manufacturer.
• Keep out of reach and sight of children.
• Tightly close the cap after each use to prevent contamination and preserve the medication's quality.
• Check the expiry date before each use. Do not use the syrup after the expiration date printed on the packaging.
• Discard unused medicine: If the syrup has changed in color, consistency, or smell, or if the bottle has been open for more than the recommended period (usually 6 months), dispose of it safely.

Always follow local regulations or ask a pharmacist on how to dispose of expired or unused medication.