LIPANTHYL 145 Tablets/Film-coated

What is LIPANTHYL 145

LIPANTHYL 145 mg contains Fenofibrate, a medication used to treat abnormal lipid levels in the blood. It belongs to the fibrate class of lipid-lowering agents and is commonly prescribed for managing high triglycerides, mixed dyslipidemia, and to reduce the risk of cardiovascular disease by improving cholesterol profiles.

• Therapeutic class: Lipid-regulating agent (Fibrate)
• Indications: Hypertriglyceridemia, mixed hyperlipidemia, prevention of cardiovascular events
• Action: Activates peroxisome proliferator-activated receptor alpha (PPARα), enhancing breakdown of triglycerides and increasing HDL cholesterol
• Formulation: Hard gelatin capsules designed for oral use

How to use LIPANTHYL 145

Take LIPANTHYL exactly as prescribed by your doctor, usually in combination with dietary modifications and lifestyle changes such as exercise and smoking cessation.

• Route: Oral
• Dosage: One capsule once daily, preferably with a meal to improve absorption
• Administration: Swallow capsules whole with water; do not crush or chew
• Compliance: Regular and consistent use is important for optimal results
• Consultation: Inform your healthcare provider about all medications and medical conditions before starting treatment

Mode of Action LIPANTHYL 145

Fenofibrate works by activating PPARα receptors, which regulate lipid metabolism by increasing the oxidation of fatty acids and removal of triglyceride-rich lipoproteins from the bloodstream. This leads to reduced triglyceride levels and increased HDL cholesterol, improving the overall lipid profile.

• Target: PPARα receptors in the liver and muscle tissues
• Effect: Enhanced lipolysis and clearance of triglycerides
• Result: Decreased plasma triglycerides and elevated HDL cholesterol

LIPANTHYL 145 Interactions LIPANTHYL 145

Several medications can interact with fenofibrate, potentially altering its effectiveness or increasing side effects.

• Anticoagulants (e.g., warfarin): Increased bleeding risk; close monitoring required
• Statins: Increased risk of muscle toxicity; use cautiously and monitor for symptoms
• Immunosuppressants (e.g., cyclosporine): Increased risk of kidney toxicity
• Diabetes medications: May affect blood sugar control; monitor accordingly

Dosage of LIPANTHYL 145

The usual adult dosage is one 145 mg capsule daily. Adjustments may be needed for renal impairment or based on patient response.

• Adults: 145 mg once daily with food
• Renal impairment: Use with caution; dose modification may be necessary
• Elderly patients: Close monitoring recommended
• Do not exceed: The prescribed dose to avoid toxicity

Possible side effects of LIPANTHYL 145

• Common: Headache, gastrointestinal upset (nausea, abdominal pain, diarrhea)
• Muscle pain or weakness (myopathy)
• Elevated liver enzymes
• Rare but serious: Gallstones, allergic reactions, pancreatitis

LIPANTHYL 145 Contraindications LIPANTHYL 145

• Hypersensitivity to fenofibrate or any capsule components
• Severe liver or kidney disease
• Gallbladder disease
• Pregnancy and breastfeeding
• Primary biliary cirrhosis

Storage of LIPANTHYL 145

• Store at room temperature (20°C - 25°C)
• Protect from moisture, heat, and direct sunlight
• Keep out of reach of children
• Do not use after the expiration date