LIDAPRIM ? Tablets

What is LIDAPRIM ?

LIDAPRIM is a prescription medication that contains a combination of two active ingredients: Co-trimoxazole, which includes Sulfamethoxazole and Trimethoprim. This medication belongs to the class of antibiotics and is used to treat a variety of bacterial infections. It is commonly prescribed for respiratory infections, urinary tract infections (UTIs), gastrointestinal infections, and certain types of skin infections.

• Generic Name: Co-trimoxazole (Sulfamethoxazole, Trimethoprim)
• Form: Tablets
• Size: 20 tablets
• Indications: Respiratory infections, urinary tract infections (UTIs), gastrointestinal infections, and skin infections

Co-trimoxazole works by inhibiting the bacterial enzymes responsible for synthesizing folic acid, a substance essential for bacterial growth. By disrupting folic acid production, LIDAPRIM prevents the bacteria from multiplying, thereby stopping the infection.

How to use LIDAPRIM ?

LIDAPRIM should be used as directed by your healthcare provider. It is important to complete the full course of therapy to ensure that the infection is fully treated, even if symptoms improve before the course is finished.

• Administration: Take the tablets orally, usually with a full glass of water, and with or without food.
• Recommended Dose: Typically, the usual dose is one tablet taken twice a day, but the dose may vary based on the specific infection being treated.
• Consistency: It is best to take the medication at the same time each day to help remember your dose.
• Missed Dose: If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses to make up for a missed dose.

Always follow your healthcare provider’s specific instructions on dosage and treatment duration.

Mode of Action LIDAPRIM ?

LIDAPRIM combines two antimicrobial agents, Sulfamethoxazole and Trimethoprim, to provide a broad-spectrum antibiotic effect. Each component works by interfering with different steps of bacterial folic acid synthesis, an essential process for bacterial cell growth.

• Sulfamethoxazole: This compound inhibits dihydropteroate synthase, an enzyme responsible for synthesizing folic acid in bacteria.
• Trimethoprim: Trimethoprim works by inhibiting another enzyme in the folic acid synthesis pathway, dihydrofolate reductase. This action helps prevent the bacteria from synthesizing the necessary building blocks for DNA and protein production.
• Result: The dual mechanism of action from Sulfamethoxazole and Trimethoprim makes LIDAPRIM effective against a wide range of bacterial infections, as it disrupts two key steps in bacterial growth.

This synergistic effect of the two components helps to prevent the development of bacterial resistance, making LIDAPRIM an effective antibiotic for treating various infections.

LIDAPRIM ? Interactions LIDAPRIM ?

LIDAPRIM may interact with other medications, which can alter its effectiveness or increase the risk of side effects. It is important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements.

• Anticoagulants: LIDAPRIM may increase the effects of blood thinners like warfarin, leading to an increased risk of bleeding.
• Diuretics: Using LIDAPRIM with diuretics (especially thiazides) can increase the risk of developing low potassium levels (hypokalemia).
• Other Antibiotics: Combining LIDAPRIM with other antibiotics that also affect folic acid synthesis may increase the risk of side effects.
• Anticonvulsants: Medications like phenytoin, which are used for epilepsy, may have altered levels in the blood when combined with LIDAPRIM.

Always disclose all medications to your healthcare provider to avoid potential interactions and ensure the safe use of LIDAPRIM.

Dosage of LIDAPRIM ?

The dosage of LIDAPRIM is determined by your healthcare provider based on the specific infection being treated, your overall health, and your response to the medication.

• Usual Dose: One tablet twice a day for most infections.
• Duration: The length of treatment typically ranges from 5 to 14 days depending on the infection.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose. Do not take two doses at once.

Do not change the dose or stop taking LIDAPRIM without consulting your healthcare provider.

Possible side effects of LIDAPRIM ?

While LIDAPRIM is generally well tolerated, like all medications, it can cause side effects. If you experience any of the following, contact your healthcare provider immediately.

• Common Side Effects: Nausea, vomiting, diarrhea, loss of appetite, rash
• Less Common Side Effects: Headache, dizziness, fever, mouth sores
• Serious Side Effects: Severe allergic reactions (swelling, rash, difficulty breathing), jaundice (yellowing of the skin or eyes), blood disorders (such as low white blood cell count, low platelet count), or signs of severe gastrointestinal problems (abdominal pain, persistent diarrhea).

If you experience any serious side effects, seek medical attention immediately.

LIDAPRIM ? Contraindications LIDAPRIM ?

• Allergic Reaction: Do not take LIDAPRIM if you are allergic to Sulfamethoxazole, Trimethoprim, or any other ingredients in the medication.
• Severe Kidney or Liver Disease: LIDAPRIM should be used with caution or avoided in patients with severe liver or kidney impairment.
• Pregnancy and Breastfeeding: LIDAPRIM should only be used during pregnancy if clearly needed, and it should be avoided during the first trimester. It may be excreted in breast milk, so breastfeeding mothers should consult their healthcare provider before use.
• Blood Disorders: LIDAPRIM should be avoided in patients with a history of blood disorders such as aplastic anemia or severe anemia.

Always consult with your healthcare provider to determine if LIDAPRIM is safe for you, particularly if you have any underlying health conditions.

Storage of LIDAPRIM ?

• Store LIDAPRIM tablets at room temperature (15°C–30°C or 59°F–86°F), away from heat, moisture, and direct sunlight.
• Keep the medication out of reach of children.
• Do not use after the expiration date printed on the packaging.

Dispose of unused medication according to local disposal guidelines to ensure safety.