ACLONIA 70mg/5,600 IU Tablet

What is ACLONIA 70mg/5,600 IU

ACLONIA 70mg/5,600 IU is a combination medication containing Alendronic acid (70 mg) and Cholecalciferol (Vitamin D3, 5,600 IU). It's primarily used to treat and prevent osteoporosis in postmenopausal women and men at increased risk of bone fractures. Key Components: Alendronic Acid: A bisphosphonate that inhibits bone resorption by osteoclasts, leading to increased bone mineral density. Cholecalciferol (Vitamin D3): Enhances calcium absorption in the gut, essential for bone formation and maintenance. Indications: Treatment of osteoporosis in postmenopausal women. Increase bone mass in men with osteoporosis. Reduce the risk of vertebral and hip fractures. Farmaco This combination simplifies therapy by integrating both bone-strengthening and supportive vitamin treatment into a single weekly tablet.

How to use ACLONIA 70mg/5,600 IU

Proper administration of ACLONIA is crucial to maximize its benefits and minimize potential side effects, especially those affecting the gastrointestinal tract. Administration Guidelines: Dosage: Take one tablet once weekly on the same day each week. Timing: Take the tablet first thing in the morning, at least 30 minutes before any food, drink (except plain water), or other medications. Method: Swallow the tablet whole with a full glass (at least 200 ml) of plain water. Do not chew, crush, or let the tablet dissolve in your mouth. Posture: Remain upright (sitting or standing) for at least 30 minutes after taking the tablet. Missed Dose: If you forget a dose, take it the next morning after you remember. Do not take two tablets on the same day. iMedi Additional Recommendations: Ensure adequate calcium and vitamin D intake during therapy. Maintain good oral hygiene and have regular dental check-ups

Mode of Action ACLONIA 70mg/5,600 IU

ACLONIA combines two agents that work synergistically to improve bone health: Alendronic Acid: Binds to hydroxyapatite in bone, inhibiting osteoclast-mediated bone resorption. Reduces bone turnover, leading to a net gain in bone mass. Cholecalciferol (Vitamin D3): Enhances intestinal absorption of calcium and phosphate. Maintains serum calcium and phosphate levels, promoting bone mineralization. Together, these components help strengthen bones and reduce the risk of fractures.

ACLONIA 70mg/5,600 IU Interactions ACLONIA 70mg/5,600 IU

Several substances can interact with ACLONIA, affecting its efficacy or increasing side effects: Potential Interactions: Calcium supplements, antacids, iron, magnesium: Can interfere with Alendronic acid absorption. Take these at least 30 minutes after ACLONIA. NSAIDs (e.g., ibuprofen, naproxen): May increase the risk of gastrointestinal irritation. Glucocorticoids (e.g., prednisone): Increase the risk of osteoporosis and may necessitate vitamin D supplementation. Diuretics (e.g., thiazides): May increase calcium levels when used with Vitamin D, potentially leading to hypercalcemia. Vitamin D analogs (e.g., calcitriol): Caution advised to prevent overdose or toxicity. Food and beverages: Aside from plain water, anything taken simultaneously can reduce Alendronic acid’s absorption. Always inform your healthcare provider about all medications and supplements you are taking.

Dosage of ACLONIA 70mg/5,600 IU

Standard Dosage: Adults: One tablet orally once weekly. Special Populations: Elderly: No dosage adjustment required solely based on age; however, renal function should be considered. Renal Impairment: Contraindicated in patients with creatinine clearance <35 mL/min. Use with caution in mild-to-moderate renal impairment. Missed Dose: If a dose is missed, take it the following morning and return to the original schedule the next week. Ensure adequate calcium and vitamin D intake during therapy, especially if dietary intake is insufficient.

Possible side effects of ACLONIA 70mg/5,600 IU

Like all medications, ACLONIA can cause side effects, although not everyone will experience them. Common Side Effects: Gastrointestinal: Esophageal irritation, pain, or ulceration. Abdominal pain, nausea, indigestion, or constipation. Vomiting or flatulence. Musculoskeletal: Joint, bone, or muscle pain, sometimes severe. Hypocalcemia Symptoms: Muscle spasms or cramps. Tingling sensations in fingers or around the mouth. Allergic Reactions: Rash, pruritus, swelling, or anaphylactic reactions (rare). Others: Headache, dizziness, or fatigue. Seek immediate medical attention if you experience severe side effects or signs of an allergic reaction.

ACLONIA 70mg/5,600 IU Contraindications ACLONIA 70mg/5,600 IU

ACLONIA should not be used in certain patients due to potential risks: Hypocalcemia: Must be corrected before starting treatment. Esophageal abnormalities: Such as strictures or achalasia that delay esophageal emptying. Inability to sit or stand upright for at least 30 minutes: Increases the risk of esophageal irritation. Renal impairment: Severe renal dysfunction (creatinine clearance <35 mL/min). Hypersensitivity: To Alendronate, Vitamin D3, or any tablet excipients. Hypercalcemia or Vitamin D toxicity: May worsen these conditions. Pregnancy and Breastfeeding: Not intended for use in pregnant or breastfeeding women. Medex Consult your healthcare provider before starting ACLONIA to ensure it's appropriate for you.

Storage of ACLONIA 70mg/5,600 IU

Proper storage ensures the stability and safety of ACLONIA tablets: Temperature: Store below 30°C (86°F). Humidity: Store in a dry place. Light: Protect from direct light. Packaging: Keep the tablets in the original blister until use to protect from moisture. Keep out of reach of children: Accidental ingestion can lead to serious health issues. Do not use past the expiry date: Check the packaging for the expiration date before use. Discard any unused or expired medicine according to local pharmacy regulations.