Paget's disease of bone

Overview Of Paget's disease of bone

Paget's disease of bone is a chronic disorder that causes abnormal bone remodeling. The bone is broken down and rebuilt more quickly than normal, leading to weakened bones.

Causes of Paget's disease of bone

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• Genetic Factors: A genetic predisposition is thought to play a role. -
• Environmental Factors: Viral infections may trigger the disease in genetically susceptible individuals.

Risk Factors of Paget's disease of bone

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• Age: Most commonly affects individuals over
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• Family History: A genetic component is likely. -
• Race: More common in people of European descent.

Prevention of Paget's disease of bone

• - Early Diagnosis: Through imaging and blood tests. - Bisphosphonate Therapy: To slow disease progression. - Regular Monitoring: To assess the effectiveness of treatment.

Prognosis of Paget's disease of bone

• - With treatment, many individuals experience improved bone health and reduced pain. If untreated, Paget's disease can lead to bone deformities and complications.

Complications of Paget's disease of bone

• - Fractures - Arthritis due to joint damage. - Hearing Loss if the skull is involved.

Related Diseases of Paget's disease of bone

• - Osteopetrosis: A condition that causes abnormally dense bones. - Osteoporosis: A condition involving decreased bone density and fragility.

Treatment of Paget's disease of bone

- **Bisphosphonates**: To slow bone turnover. - **Calcitonin**: To regulate bone resorption. - **Pain Management**: Including analgesics for bone pain.