What is ACLOHERP 400 mg
ACLOHERP 400 mg is an oral antiviral medication containing Aciclovir as its active ingredient. It is primarily used to treat infections caused by herpes viruses. These viruses can cause a variety of conditions, including:
- Herpes simplex virus (HSV) infections: such as cold sores (herpes labialis), genital herpes, and herpes keratitis.
- Varicella-zoster virus (VZV) infections: including chickenpox and shingles (herpes zoster).
Aciclovir works by interfering with the replication process of the herpes viruses, thereby reducing the severity and duration of symptoms. ACLOHERP tablets come in 400 mg strength, often supplied in packs of 25 tablets (5 tablets per blister, 5 blisters per pack), offering a convenient dosage form for outpatient therapy.
This medication is widely prescribed for both the treatment of active outbreaks and for suppressive therapy in recurrent herpes infections, helping to prevent future outbreaks and reduce viral shedding.
How to use ACLOHERP 400 mg
Proper administration of ACLOHERP is essential to maximize its effectiveness:
- Dosage and Schedule: Follow your healthcare provider’s prescription carefully. It’s typically taken 3-5 times daily depending on the condition treated.
- Swallow tablets whole: Do not crush or chew. Take with a full glass of water.
- Timing: Take doses at evenly spaced intervals to maintain consistent drug levels in the bloodstream.
- Food: ACLOHERP can be taken with or without food; however, taking it with food may help reduce stomach upset.
- Complete the course: Even if symptoms improve, do not stop treatment early unless advised by your doctor.
- Hydration: Drink plenty of fluids during treatment to reduce the risk of kidney side effects.
If a dose is missed, take it as soon as remembered unless it’s near the time for the next dose—do not double the dose.
Mode of Action ACLOHERP 400 mg
Aciclovir is a synthetic nucleoside analogue that specifically targets herpes viruses through the following mechanism:
- It is selectively phosphorylated by viral thymidine kinase inside infected cells, converting it into aciclovir monophosphate.
- Cellular enzymes then convert it to aciclovir triphosphate, the active form.
- Aciclovir triphosphate competitively inhibits viral DNA polymerase, an enzyme essential for viral DNA synthesis.
- Incorporation of aciclovir triphosphate into viral DNA leads to premature chain termination.
This highly selective mechanism means ACLOHERP disrupts viral replication with minimal effects on host DNA, making it effective and generally well-tolerated.
ACLOHERP 400 mg Interactions ACLOHERP 400 mg
Although Aciclovir is generally safe, it may interact with certain drugs or conditions, so caution is advised:
- Nephrotoxic drugs: Concomitant use with other medications that can damage kidneys (e.g., aminoglycosides, cyclosporine, NSAIDs) increases risk of renal toxicity.
- Probenecid: Can decrease the renal clearance of aciclovir, increasing its blood levels.
- Other antivirals: Combining with drugs like valacyclovir or famciclovir requires monitoring for enhanced toxicity or side effects.
- Live vaccines: Immune response to live varicella or zoster vaccines may be reduced.
Always inform your healthcare provider of all medications and supplements you are taking to avoid adverse interactions.
Dosage of ACLOHERP 400 mg
The dosage depends on the specific infection and patient factors such as age and kidney function:
- Herpes simplex (initial episode): 200 mg orally five times daily for 10 days.
- Recurrent herpes simplex: 200 mg orally five times daily for 5 days.
- Suppressive therapy for recurrent genital herpes: 400 mg twice daily or 200 mg four times daily, for up to 12 months.
- Varicella-zoster virus (shingles): 800 mg orally five times daily for 7-10 days (note: higher dose than 400 mg tablets, may require different formulation).
Renal impairment: Dose adjustment is necessary based on creatinine clearance levels; always consult a healthcare provider.
Possible side effects of ACLOHERP 400 mg
Aciclovir is generally well tolerated. Possible side effects include:
- Common side effects: headache, nausea, diarrhea, abdominal pain, and fatigue.
- Neurological effects: dizziness, confusion, hallucinations, particularly in elderly or renal-impaired patients.
- Renal toxicity: rare cases of kidney dysfunction, especially with dehydration or overdose.
- Hypersensitivity reactions: rash, itching, or anaphylaxis (rare).
If severe side effects or allergic reactions occur, seek immediate medical attention.
ACLOHERP 400 mg Contraindications ACLOHERP 400 mg
ACLOHERP should not be used in patients with:
- Known hypersensitivity to Aciclovir or any ingredient in the tablet.
- Severe renal impairment unless dose adjustment is made.
- Patients with a history of hypersensitivity reactions to other antivirals of the same class.
- Use with caution during pregnancy and breastfeeding—consult a healthcare provider.
Careful assessment is required before prescribing to elderly or immunocompromised patients.
Storage of ACLOHERP 400 mg
- Store tablets at room temperature between 20°C to 25°C (68°F to 77°F).
- Keep in a dry place away from direct sunlight and moisture.
- Keep out of reach of children.
- Do not use after the expiration date printed on the pack.
- Do not store tablets in the bathroom or near water sources.
Proper storage helps maintain the medication’s effectiveness and safety.
ACLOHERP 400 mg features an exceptional active ingredient renowned for its potent effects, comprising Aciclovir. This powerful formulation provides a superior solution for addressing diverse health concerns. With 400 mg/Tablet concentration and an easily manageable Tablet, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ACLOHERP 400 mg .
Welcome to Dwaey, specifically on ACLOHERP 400 mg page.
This medicine contains an important and useful components, as it consists of Aciclovir.
ACLOHERP 400 mg is available in the market in concentration 400 mg/Tablet and in the form of Tablet.
AUROBINDO PHARMA FZ LLC is the producer of ACLOHERP 400 mg and it is imported from UAE,
The most popular alternatives of ACLOHERP 400 mg are listed downward .
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Frequently Asked Questions
ACLOHERP 400 mg should be stored according to the instructions provided by AUROBINDO PHARMA FZ LLC.
In general, it is recommended to store ACLOHERP 400 mg in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ACLOHERP 400 mg may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ACLOHERP 400 mg for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ACLOHERP 400 mg . Some medications, including
ACLOHERP 400 mg , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ACLOHERP 400 mg , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ACLOHERP 400 mg without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ACLOHERP 400 mg if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ACLOHERP 400 mg during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 400 mg/Tablet,
and the specific recommendations of AUROBINDO PHARMA FZ LLC.
The effects of ACLOHERP 400 mg on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 400 mg/Tablet, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ACLOHERP 400 mg with or without food may vary depending on the medication
and the recommendations of AUROBINDO PHARMA FZ LLC. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ACLOHERP 400 mg in children or elderly individuals may depend on various factors, including
the specific medication, type Tablet, and the recommendations of AUROBINDO PHARMA FZ LLC. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ACLOHERP 400 mg in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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