ACIDIC HD CONCENTRATE SW 178A Dialysis Fluid

What is ACIDIC HD CONCENTRATE SW 178A

ACIDIC HD CONCENTRATE SW 178A is a medical-grade acidic concentrate used in the preparation of dialysate for hemodialysis. It is designed to be mixed with a bicarbonate concentrate and purified water to create a final dialysis solution that facilitates the removal of waste products and excess electrolytes from the blood of patients with renal failure. Composition per liter: Sodium Chloride Potassium Chloride Calcium Chloride Dihydrate Magnesium Chloride Hexahydrate Glucose Monohydrate Glacial Acetic Acid Medex +1 MedEasy +1 Key Features: Form: Liquid acidic concentrate Packaging: 6-liter canister Usage: For use in three-stream proportioning hemodialysis systems PMC +4 PMC +4 Scribd +4 PMC +2 pharma-china.en.made-in-china.com +2 PMC +2 This concentrate plays a crucial role in maintaining the acid-base balance and electrolyte composition of the dialysate, ensuring effective and safe hemodialysis sessions.

How to use ACIDIC HD CONCENTRATE SW 178A

ACIDIC HD CONCENTRATE SW 178A is intended for use in hemodialysis machines equipped with a three-stream proportioning system. It must be mixed with a bicarbonate concentrate and purified water to prepare the final dialysate solution. Preparation Steps: Connection: Connect the 6-liter canister of acidic concentrate to the designated port on the dialysis machine. Mixing Ratios: The standard mixing ratio is typically 1 part acidic concentrate to 1.83 parts bicarbonate concentrate to 34 parts purified water (1:1.83:34). Quality Checks: Ensure that the dialysis machine is calibrated correctly and that the conductivity and pH of the final dialysate are within the prescribed ranges. Precautions: Do not use the acidic concentrate alone; it must be properly diluted with bicarbonate concentrate and water. Inspect the canister for any signs of damage or contamination before use. Only trained healthcare professionals should handle and prepare the dialysate solution. Proper preparation and handling are essential to ensure patient safety and the effectiveness of the hemodialysis treatment.

Mode of Action ACIDIC HD CONCENTRATE SW 178A

ACIDIC HD CONCENTRATE SW 178A contributes to the dialysate's ability to correct metabolic imbalances in patients undergoing hemodialysis. Mechanism: Acid-Base Balance: The glacial acetic acid in the concentrate serves as a buffer precursor. Once in the body, acetate is metabolized to bicarbonate, helping to correct metabolic acidosis commonly seen in renal failure patients. Electrolyte Regulation: The inclusion of electrolytes such as sodium, potassium, calcium, and magnesium helps maintain proper plasma concentrations, preventing complications like arrhythmias or muscle cramps. Glucose Provision: Glucose monohydrate provides an energy source, which can be particularly beneficial in preventing hypoglycemia during dialysis sessions. By facilitating the removal of waste products and excess electrolytes while maintaining essential plasma components, the dialysate prepared with this concentrate supports the body's homeostasis during hemodialysis.

ACIDIC HD CONCENTRATE SW 178A Interactions ACIDIC HD CONCENTRATE SW 178A

While ACIDIC HD CONCENTRATE SW 178A is not administered directly to patients, the dialysate it helps produce can interact with various medications and physiological processes. Potential Interactions: Medication Clearance: Hemodialysis can remove certain medications from the bloodstream, reducing their efficacy. Drugs with low molecular weight and low protein binding are particularly susceptible. Electrolyte-Modifying Drugs: Medications that affect electrolyte levels, such as diuretics or ACE inhibitors, may require dosage adjustments to prevent imbalances during dialysis. Acid-Base Affecting Agents: Agents that influence acid-base balance, like sodium bicarbonate or acetazolamide, may have altered effects when used concurrently with acetate-containing dialysate. Clinical Considerations: Regular monitoring of drug levels and patient response is essential. Coordination between nephrologists and pharmacists can help manage potential interactions effectively. Understanding these interactions ensures that patients receive optimal therapeutic benefits from both dialysis and their medication regimens.

Dosage of ACIDIC HD CONCENTRATE SW 178A

The dosage of ACIDIC HD CONCENTRATE SW 178A refers to the volume used in preparing the dialysate solution for each hemodialysis session. Standard Dosage: Typically, 5 liters of acidic concentrate are used per dialysis session, but this may vary based on the dialysis machine's specifications and the patient's needs. MedEasy Mixing Ratios: The concentrate is mixed with bicarbonate concentrate and purified water in a ratio determined by the dialysis machine's settings, commonly 1:1.83:34. PMC Adjustments: The exact volume and mixing ratios may be adjusted based on: Patient's electrolyte levels Presence of comorbid conditions Specific treatment goals pharma-china.en.made-in-china.com +7 metrohm.com +7 Scribd +7 Monitoring: Regular assessment of the dialysate's composition, including pH and conductivity, is essential to ensure patient safety and treatment efficacy. Proper dosing and preparation of the dialysate are critical components of effective hemodialysis therapy.

Possible side effects of ACIDIC HD CONCENTRATE SW 178A

While ACIDIC HD CONCENTRATE SW 178A itself is not directly administered to patients, the dialysate prepared from it can lead to side effects if not properly balanced. Common Side Effects: Electrolyte Imbalances: Hypokalemia or hyperkalemia Hypocalcemia or hypercalcemia Fluid Shifts: Hypotension Muscle cramps Dizziness Medex +2 PMC +2 pharma-china.en.made-in-china.com +2 Acid-Base Disturbances: Metabolic alkalosis if acetate is metabolized excessively Rare Side Effects: Allergic Reactions: Though uncommon, hypersensitivity to components may occur. Preventive Measures: Regular monitoring of patient's vital signs and laboratory values during dialysis sessions. Adjusting the dialysate composition based on individual patient needs. Awareness and prompt management of these potential side effects are essential for safe and effective hemodialysis treatment.

ACIDIC HD CONCENTRATE SW 178A Contraindications ACIDIC HD CONCENTRATE SW 178A

ACIDIC HD CONCENTRATE SW 178A should not be used in certain situations where its components may pose risks to the patient. Absolute Contraindications: Hypersensitivity: Known allergy to any of the concentrate's components. Relative Contraindications: Severe Hyperkalemia: If the dialysate's potassium concentration is too high, it may exacerbate the condition. Severe Hypokalemia: Using a dialysate with low potassium concentration can worsen hypokalemia. Uncontrolled Coagulation Disorders: Acetate metabolism may affect coagulation parameters. Clinical Considerations: Thorough patient evaluation before initiating dialysis with this concentrate. Adjusting the dialysate composition to suit individual patient conditions. Identifying and respecting these contraindications is vital to prevent adverse outcomes during hemodialysis.

Storage of ACIDIC HD CONCENTRATE SW 178A

Proper storage of ACIDIC HD CONCENTRATE SW 178A is essential to maintain its efficacy and safety. Storage Conditions: Temperature: Store at room