ACEFLAM 100 mg Tablets/Film-coated

What is ACEFLAM 100 mg

ACEFLAM 100 mg is a prescription medication containing Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions such as:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis

It works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins, substances that cause pain and inflammation.

How to use ACEFLAM 100 mg

To ensure effective and safe use of ACEFLAM 100 mg:

• Dosage: Take one tablet (100 mg) twice daily, preferably in the morning and evening.
• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew.
• With Food: Take with or after meals to minimize gastrointestinal discomfort.
• Consistency: Take at the same times each day to maintain steady blood levels.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed one. Do not double up.

Always follow your healthcare provider's instructions and do not adjust your dose without consulting them.

Mode of Action ACEFLAM 100 mg

ACEFLAM 100 mg works by:

• Inhibiting COX Enzymes: Blocks cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins.
• Reducing Inflammation: Decreases inflammation, swelling, and pain associated with musculoskeletal disorders.

This dual action provides both analgesic and anti-inflammatory effects, making it effective in managing various forms of arthritis.

ACEFLAM 100 mg Interactions ACEFLAM 100 mg

ACEFLAM 100 mg may interact with several medications:

• Anticoagulants (e.g., Warfarin): Increased risk of bleeding.
• Diuretics: May reduce diuretic efficacy and increase nephrotoxicity risk.
• Antihypertensives: NSAIDs can diminish the effect of blood pressure medications.
• Lithium: May increase lithium levels, leading to toxicity.
• Methotrexate: Increased risk of methotrexate toxicity.
• Other NSAIDs or Corticosteroids: Heightened risk of gastrointestinal side effects.

Always inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.

Dosage of ACEFLAM 100 mg

The typical dosage for adults is:

• 100 mg twice daily: One tablet in the morning and one in the evening.

Dosage adjustments may be necessary for:

• Elderly patients: Use the lowest effective dose for the shortest duration.
• Patients with hepatic or renal impairment: Use with caution and under medical supervision.

Not recommended for use in children due to limited safety and efficacy data.

Possible side effects of ACEFLAM 100 mg

Common side effects include:

• Gastrointestinal issues: Nausea, indigestion, abdominal pain, diarrhea.
• Central nervous system: Dizziness, headache.
• Skin reactions: Rash, itching.

Serious side effects (seek immediate medical attention):

• Gastrointestinal bleeding: Black or bloody stools, vomiting blood.
• Cardiovascular events: Chest pain, shortness of breath.
• Hepatic or renal impairment: Yellowing of the skin or eyes, dark urine.
• Allergic reactions: Swelling of the face, lips, or throat; difficulty breathing.

Report any unusual or persistent symptoms to your healthcare provider promptly.

ACEFLAM 100 mg Contraindications ACEFLAM 100 mg

Do not use ACEFLAM 100 mg if you have:

• Allergy to Aceclofenac or other NSAIDs.
• History of asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs.
• Active or history of recurrent peptic ulcer or gastrointestinal bleeding.
• Severe hepatic, renal, or cardiac impairment.
• Pregnancy (especially third trimester) or breastfeeding.

Always consult your healthcare provider before starting or stopping any medication.

Storage of ACEFLAM 100 mg

To maintain the efficacy of ACEFLAM 100 mg:

• Store at room temperature: Between 20°C to 25°C (68°F to 77°F).
• Keep in original packaging: Protects from moisture and light.
• Out of reach: Store away from children and pets.
• Do not use: Beyond the expiration date printed on the packaging.
• Disposal: Dispose of unused or expired medication according to local regulations or consult your pharmacist.

Do not store in the bathroom or areas with high humidity.