What is 5% DEXTROSE INFUSION [PSI]
5% Dextrose Infusion [PSI] is a sterile, intravenous solution containing 5% dextrose (as monohydrate) dissolved in water, supplied in a 100ml non-PVC bag. This infusion serves primarily as a source of fluid and energy, especially in clinical settings where patients cannot consume oral nutrition. It is a clear, isotonic solution initially, which becomes hypotonic once the dextrose is metabolized.
- Composition: 5 grams of dextrose per 100 ml of solution, providing a 5% concentration.
- Purpose: It delivers free water and calories in the form of glucose to meet basal metabolic needs and maintain hydration.
- Clinical Use: Used to treat dehydration, hypoglycemia, and as maintenance fluid therapy in patients unable to take oral fluids.
- Additional Roles: It serves as a vehicle for intravenous medications and helps in preventing catabolism during fasting or illness.
- Packaging: The non-PVC bag reduces the risk of plasticizer leaching and makes it safer for sensitive patient populations.
How to use 5% DEXTROSE INFUSION [PSI]
The infusion should be administered under strict medical supervision with attention to patient status:
- Route of Administration: Intravenous infusion via a suitable venous access device, either peripheral or central line depending on duration and patient condition.
- Preparation: Inspect the infusion bag to ensure clarity, absence of particulates, and intact packaging before use.
- Infusion Rate: Typically infused slowly, the rate depends on clinical indication and patient tolerance; commonly between 50 to 150 ml per hour.
- Compatibility: Verify compatibility with any other intravenous medications administered concurrently to avoid precipitation or inactivation.
- Monitoring: Regular monitoring of blood glucose, fluid balance, and electrolyte levels is essential to avoid complications.
- Duration: Continue infusion until oral intake resumes or as clinically indicated, with periodic reassessment of patient condition.
Mode of Action 5% DEXTROSE INFUSION [PSI]
The therapeutic effects of 5% Dextrose Infusion stem mainly from its glucose content and its fluid properties:
- Energy Supply: Dextrose is rapidly absorbed by cells and metabolized through glycolysis to produce ATP, the main energy currency in cells.
- Hydration: The aqueous solution provides free water which distributes across the body’s compartments, aiding in hydration of intracellular and extracellular spaces.
- Osmolarity Changes: The infusion is initially isotonic, but as dextrose is metabolized, the remaining free water creates a hypotonic environment, which helps rehydrate cells.
- Metabolic Effects: Helps prevent protein catabolism during fasting or stress by supplying an energy substrate.
- Physiological Impact: Supports metabolic functions and maintains adequate circulatory volume when given in appropriate quantities.
5% DEXTROSE INFUSION [PSI] Interactions 5% DEXTROSE INFUSION [PSI]
This infusion can interact with various medications and physiological conditions, necessitating careful monitoring:
- Insulin and Antidiabetic Agents: Dextrose increases blood glucose levels, potentially reducing the effectiveness of hypoglycemic drugs.
- Diuretics: May alter electrolyte balance; concurrent use requires monitoring to prevent imbalances.
- Potassium and Cardiac Glycosides: Changes in potassium levels caused by dextrose metabolism can affect drugs like digoxin, increasing toxicity risk.
- Intravenous Medications: Check for compatibility before mixing or co-infusing to avoid precipitation or loss of efficacy.
- Patients with Impaired Glucose Metabolism: Infusion can worsen hyperglycemia or cause fluctuations in blood sugar levels.
- Renal and Cardiac Impairment: Fluid management requires adjustment to avoid overload and adverse events.
Dosage of 5% DEXTROSE INFUSION [PSI]
The dosage should be individualized based on patient needs, clinical status, and metabolic requirements:
- Adults: Typical maintenance doses range from 1000 to 3000 ml per day, adjusted according to hydration status and caloric needs.
- Pediatric Patients: Dose calculated per weight and condition; close monitoring of glucose and fluids is vital.
- Infusion Rate: Commonly between 50-150 ml/hr, with adjustments based on patient tolerance and clinical response.
- Special Populations: Reduced rates or volumes are recommended for patients with cardiac or renal impairment.
- Monitoring: Frequent reassessment of blood glucose, fluid balance, and electrolytes guides dosage adjustments.
Possible side effects of 5% DEXTROSE INFUSION [PSI]
While generally safe when used appropriately, some adverse effects may occur:
- Local Reactions: Pain, irritation, or phlebitis at the injection site.
- Hyperglycemia: Elevated blood glucose, especially in diabetic or glucose-intolerant patients.
- Fluid Overload: Risk of edema, hypertension, and pulmonary congestion, particularly in patients with heart or kidney problems.
- Electrolyte Imbalance: May cause hyponatremia or other disturbances if improperly monitored.
- Hypersensitivity: Rare allergic reactions including rash, itching, or anaphylaxis.
- Metabolic Acidosis or Alkalosis: Possible if infusion is not matched to patient metabolic needs.
5% DEXTROSE INFUSION [PSI] Contraindications 5% DEXTROSE INFUSION [PSI]
Use of this infusion is contraindicated in the following conditions:
- Known Hypersensitivity: To dextrose or any component of the solution.
- Hyperglycemia or Uncontrolled Diabetes Mellitus: Infusion may exacerbate these conditions.
- Severe Fluid Overload States: Including congestive heart failure or pulmonary edema where volume expansion is harmful.
- Increased Intracranial Pressure: Infusion may worsen cerebral edema due to free water content.
- In Patients with Lactic Acidosis or Ketoacidosis: Without proper correction of underlying causes.
Storage of 5% DEXTROSE INFUSION [PSI]
Proper storage is vital to maintain efficacy and safety:
- Temperature: Store at controlled room temperature, typically between 20-25°C (68-77°F). Avoid freezing or exposure to extreme heat.
- Packaging: Keep in the original non-PVC bag until use to prevent contamination and degradation.
- Light Protection: Protect from excessive light exposure, which may degrade the solution.
- Inspection: Prior to administration, inspect for clarity, color, and particulate matter; do not use if solution is discolored or cloudy.
- Expiration: Use before the expiry date printed on the packaging.
- Disposal: Dispose of unused or expired solution according to local medical waste regulations.
5% DEXTROSE INFUSION [PSI] features an exceptional active ingredient renowned for its potent effects, comprising Dextrose (as monohydrate). This powerful formulation provides a superior solution for addressing diverse health concerns. With 50mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 5% DEXTROSE INFUSION [PSI] .
Welcome to Dwaey, specifically on 5% DEXTROSE INFUSION [PSI] page.
This medicine contains an important and useful components, as it consists of Dextrose (as monohydrate).
5% DEXTROSE INFUSION [PSI] is available in the market in concentration 50mg/ml and in the form of Infusion/Solution for.
PHARMACEUTICAL SOLUTION INDUSTRY LTD. is the producer of 5% DEXTROSE INFUSION [PSI] and it is imported from SAUDI ARABIA,
The most popular alternatives of 5% DEXTROSE INFUSION [PSI] are listed downward .
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Active Substance
Dextrose (as monohydrate)
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Size
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Indications
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Type
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Company
PHARMACEUTICAL SOLUTION INDUSTRY LTD.
Frequently Asked Questions
5% DEXTROSE INFUSION [PSI] should be stored according to the instructions provided by PHARMACEUTICAL SOLUTION INDUSTRY LTD. .
In general, it is recommended to store 5% DEXTROSE INFUSION [PSI] in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 5% DEXTROSE INFUSION [PSI] may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 5% DEXTROSE INFUSION [PSI] for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 5% DEXTROSE INFUSION [PSI]. Some medications, including
5% DEXTROSE INFUSION [PSI], may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 5% DEXTROSE INFUSION [PSI], take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 5% DEXTROSE INFUSION [PSI] without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 5% DEXTROSE INFUSION [PSI] if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 5% DEXTROSE INFUSION [PSI] during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 50mg/ml,
and the specific recommendations of PHARMACEUTICAL SOLUTION INDUSTRY LTD. .
The effects of 5% DEXTROSE INFUSION [PSI] on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 50mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 5% DEXTROSE INFUSION [PSI] with or without food may vary depending on the medication
and the recommendations of PHARMACEUTICAL SOLUTION INDUSTRY LTD. . Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 5% DEXTROSE INFUSION [PSI] in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of PHARMACEUTICAL SOLUTION INDUSTRY LTD. . Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 5% DEXTROSE INFUSION [PSI] in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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