4 - ALL 80mg Tablets/Chewable

What is 4 - ALL 80mg

p>4 - ALL 80mg is a medication that contains Paracetamol (also known as Acetaminophen) as its active ingredient. It comes in a tablet/chewable form and is packaged as 20 tablets (2 blisters of 10 each).

Paracetamol is a widely used over-the-counter (OTC) analgesic and antipyretic. It is commonly prescribed or recommended for:

• Reducing mild to moderate pain (e.g., headaches, muscle aches, backache)
• Managing fever associated with infections like the common cold or flu
• Alleviating symptoms related to dental pain or minor injuries

The chewable form of 4 - ALL 80mg is particularly convenient for pediatric use or for individuals who have difficulty swallowing conventional tablets. It ensures quick absorption and ease of administration.

Despite its common usage, 4 - ALL 80mg should be taken responsibly, as overdosing can lead to serious liver damage. It's considered one of the safest painkillers when taken in appropriate doses.

This medicine is typically well tolerated and is recommended by health professionals globally due to its favorable safety profile, especially in comparison to non-steroidal anti-inflammatory drugs (NSAIDs).

How to use 4 - ALL 80mg

Using 4 - ALL 80mg correctly is essential to ensure safety and efficacy. The tablet/chewable format offers flexibility in administration, especially for children and the elderly.

• For chewable tablets: The tablet can be chewed completely before swallowing. Water is optional but may help with swallowing the chewed tablet.
• Without chewing: It may also be swallowed whole with water if preferred by older children or adults.

General usage guidelines:

• Follow the dosing instructions on the label or as advised by a healthcare provider.
• Can be taken with or without food.
• Do not exceed the maximum daily dose (usually 60mg/kg/day in children or 4000mg/day in adults unless specified otherwise).
• Maintain at least a 4 to 6-hour gap between doses.

Important considerations:

• For children, dose is typically calculated based on body weight. Always use proper dosing tools if giving to a child.
• Do not use multiple medications containing paracetamol at the same time to avoid accidental overdose.
• Consult a doctor if fever or pain persists for more than 3 days.

Always read the package insert or consult with a pharmacist or physician for personalized advice.

Mode of Action 4 - ALL 80mg

Paracetamol, the active ingredient in 4 - ALL 80mg, exhibits analgesic (pain-relieving) and antipyretic (fever-reducing) properties. Its precise mechanism is still being fully understood, but several pharmacological actions have been identified:

• Central inhibition of prostaglandin synthesis: Paracetamol works by inhibiting the cyclooxygenase (COX) enzyme, particularly COX-2, in the central nervous system (CNS). This action reduces the production of prostaglandins—chemical messengers involved in the sensation of pain and elevation of body temperature.
• Antipyretic effect: Paracetamol acts on the hypothalamus, the brain’s heat-regulating center, helping to lower elevated body temperatures during fever without affecting normal body temperature.
• Minimal anti-inflammatory effect: Unlike NSAIDs, paracetamol has weak peripheral anti-inflammatory action due to minimal inhibition of COX enzymes outside the CNS.

Thanks to its central action and lack of significant peripheral COX inhibition, paracetamol is generally well tolerated and does not cause gastric irritation or bleeding risks commonly associated with NSAIDs.

In summary, 4 - ALL 80mg effectively reduces pain and fever via central nervous system pathways, making it a reliable option for a wide range of symptoms in both children and adults.

4 - ALL 80mg Interactions 4 - ALL 80mg

While Paracetamol (4 - ALL 80mg) is considered relatively safe, it can interact with certain drugs, especially when used frequently or at higher doses.

Notable drug interactions include:

• Warfarin and other anticoagulants: Long-term use of paracetamol may enhance the anticoagulant effect, increasing bleeding risk.
• Enzyme-inducing drugs (e.g., phenytoin, carbamazepine, rifampin): These can increase the metabolism of paracetamol, potentially reducing its efficacy and increasing liver toxicity risk.
• Alcohol: Chronic alcohol consumption can increase the risk of liver toxicity from paracetamol, especially in high doses.
• Isoniazid: Concurrent use may enhance hepatotoxic risk.
• Lamotrigine: Paracetamol may reduce its blood levels and efficacy.

Additional considerations:

• Concurrent use of multiple OTC cold, flu, or pain medications may inadvertently lead to paracetamol overdose.
• Always inform your doctor about any other medications or supplements you are taking before using 4 - ALL 80mg.

As a rule, avoid combining 4 - ALL with other hepatotoxic agents unless medically justified.

Dosage of 4 - ALL 80mg

Correct dosing of 4 - ALL 80mg (Paracetamol) ensures safe and effective relief from pain and fever. Dosage varies depending on age, weight, and medical condition.

General pediatric dosage (based on 80mg strength):

• Children 2–3 years (10–15kg): 160mg (2 tablets) every 4–6 hours as needed
• Children 4–5 years (16–21kg): 240mg (3 tablets) every 4–6 hours
• Maximum: 4 doses (no more than 320–960mg) in 24 hours

Adult dosage (if chewable used):

• Not typically recommended due to low strength (80mg); adult patients generally use higher-strength formulations such as 500mg tablets.

Important notes:

• Do not exceed the total daily limit (60mg/kg/day in children, 4000mg/day in adults).
• Space doses at least 4 to 6 hours apart.
• Chewable tablets can be used in pediatric populations for easier administration.
• Consult a healthcare provider if symptoms persist longer than 3 days or worsen.

Always tailor the dose to the patient’s age and body weight, especially for pediatric use.

Possible side effects of 4 - ALL 80mg

4 - ALL 80mg (Paracetamol) is typically well tolerated, but like any medication, it may cause side effects in some individuals. Most are rare and mild, but serious reactions may occur with overdose or prolonged use.

Common side effects (usually mild and transient):

• Nausea
• Stomach upset
• Drowsiness
• Skin rash (rare)

Rare but serious side effects:

• Allergic reactions such as:
  • Swelling of the face, lips, or throat
  • Severe itching or rash
  • Breathing difficulty
• Hepatotoxicity (liver damage), especially with overdose or in alcoholics
• Thrombocytopenia (low platelet count) – very rare
• Stevens-Johnson Syndrome or toxic epidermal necrolysis (extremely rare)

Seek medical help if:

• Any signs of allergic reaction appear
• Symptoms persist or worsen
• Unexplained fatigue or jaundice (yellowing of skin/eyes) occurs

Using 4 - ALL 80mg within recommended doses minimizes risk of side effects significantly.

4 - ALL 80mg Contraindications 4 - ALL 80mg

Though Paracetamol is generally safe for a broad population, 4 - ALL 80mg should not be used in the following conditions:

• Known hypersensitivity: Individuals allergic to paracetamol or any excipients in the tablet.
• Severe liver impairment: Due to the hepatic metabolism of paracetamol, those with significant liver disease are at higher risk of toxicity.
• Severe renal impairment: Use with caution or avoid if kidney function is severely compromised.
• Glucose-6-phosphate dehydrogenase (G6PD) deficiency: Risk of hemolysis in some patients.
• Chronic alcoholism: Increased risk of liver damage with even therapeutic doses.

Relative contraindications or caution required:

• Patients on other hepatotoxic drugs
• Malnourished individuals
• Elderly patients with comorbidities

Always consult with a physician before administering to children under 2 years or in patients with pre-existing conditions.

Storage of 4 - ALL 80mg

Proper storage of 4 - ALL 80mg ensures that the medication maintains its effectiveness and safety.

• Storage temperature: Store at room temperature, typically between 15°C and 25°C (59°F to 77°F).
• Avoid moisture: Keep tablets in their original blister packaging to protect from humidity.
• Protect from light: Store away from direct sunlight and heat sources.
• Keep out of reach of children: Always store in a secure place, especially since the chewable format may be mistaken for candy.
• Do not use after expiration date: Check the packaging for expiry and dispose of safely once expired.

Disposal tips:

• Do not flush unused tablets down the toilet.
• Use a community drug take-back program if available, or consult a pharmacist for proper disposal methods.

Maintaining these conditions helps ensure the medicine remains effective and safe until its expiration date.