DAIVOBET Ointment

What is DAIVOBET

DAIVOBET Ointment is a topical medication that combines two active ingredients: calcipotriol and betamethasone. Calcipotriol is a synthetic derivative of vitamin D, while betamethasone is a potent corticosteroid. This combination is primarily used in the treatment of psoriasis, particularly in patients with plaque psoriasis.

Calcipotriol works by regulating the growth and differentiation of skin cells, effectively slowing down the overproduction of skin cells that characterizes psoriasis. On the other hand, betamethasone helps reduce inflammation, redness, and itching associated with the condition. Together, they provide a comprehensive approach to managing psoriasis symptoms.

How to use DAIVOBET

How to use DAIVOBET Ointment:

• Apply DAIVOBET Ointment exactly as prescribed by your healthcare provider. Typically, a small amount of the ointment is applied to the affected areas of the skin.
• Gently rub the ointment into the skin until it is fully absorbed. Avoid applying it to large areas of skin or using it on the face, groin, or underarms unless directed by your healthcare provider.
• Wash your hands after applying the ointment to avoid accidentally transferring it to other areas or to other people.
• It is usually recommended to apply DAIVOBET Ointment twice daily, but follow your doctor’s specific instructions regarding frequency and duration of use.
• If you miss a dose, apply it as soon as you remember unless it is nearly time for your next application. Do not apply more ointment to make up for a missed dose.

Mode of Action DAIVOBET

Mode of action of DAIVOBET Ointment:

DAIVOBET Ointment acts through a dual mechanism of action. Calcipotriol, as a vitamin D analogue, modulates the proliferation and differentiation of keratinocytes, the primary cell type found in the outer layer of the skin. By slowing down the excessive growth of skin cells, it helps reduce the formation of psoriasis plaques.

Betamethasone, being a potent corticosteroid, reduces inflammation by inhibiting the release of inflammatory mediators. It also helps to alleviate the itching and redness commonly associated with psoriasis flares. This combination allows for effective management of both the symptoms and underlying pathophysiology of psoriasis.

DAIVOBET Interactions DAIVOBET

Interactions with DAIVOBET Ointment:

• Inform your healthcare provider of all medications and supplements you are currently taking, as some medications may interact with the ingredients in DAIVOBET Ointment.
• Avoid using other topical medications on the same area of skin unless instructed by your healthcare provider, as this may increase the risk of side effects or reduce efficacy.
• Be cautious when using DAIVOBET with other corticosteroids, as concurrent use may increase the risk of systemic side effects associated with corticosteroid therapy.
• If you are using phototherapy (light treatment) for psoriasis, consult your doctor to ensure that using DAIVOBET does not interfere with your treatment plan.

Always discuss potential interactions with your healthcare provider before starting any new medications or treatments.

Dosage of DAIVOBET

Dosage of DAIVOBET Ointment:

The typical dosage of DAIVOBET Ointment is to apply it to the affected areas of the skin twice daily, as directed by your healthcare provider. The amount used will depend on the extent and severity of the psoriasis. Usually, a small amount is sufficient to cover the affected area thinly.

Duration of treatment varies depending on individual response, but it is generally recommended to use DAIVOBET for a limited time to minimize the risk of side effects associated with long-term corticosteroid use. Your healthcare provider will assess your condition and may suggest periodic evaluations to monitor your progress and the effectiveness of the treatment.

Do not exceed the recommended dosage or duration of treatment without consulting your healthcare provider.

Possible side effects of DAIVOBET

Possible side effects of DAIVOBET Ointment:

• Common side effects: Some users may experience mild irritation at the application site, including redness, dryness, or a burning sensation. These effects are usually temporary and may resolve with continued use.
• Serious side effects: Prolonged use of DAIVOBET Ointment can lead to systemic absorption of betamethasone, potentially causing side effects such as Cushing’s syndrome, adrenal suppression, or worsening of existing infections. It is crucial to monitor for signs of these conditions, especially with extended use.
• Allergic reactions: Although rare, some individuals may develop an allergic reaction to DAIVOBET, presenting as severe rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if these symptoms occur.

If you notice any severe or unusual side effects while using DAIVOBET Ointment, contact your healthcare provider for advice.

DAIVOBET Contraindications DAIVOBET

Contraindications for DAIVOBET Ointment:

• Do not use DAIVOBET Ointment if you are allergic to calcipotriol, betamethasone, or any of the other ingredients in the formulation.
• It is contraindicated in individuals with certain skin infections, including viral (such as herpes), bacterial, or fungal infections, unless these infections are being treated simultaneously.
• Patients with a history of hypercalcemia or vitamin D toxicity should avoid using this ointment due to the risk of elevated calcium levels.
• Do not apply DAIVOBET Ointment to open wounds or broken skin.
• Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using this medication, as it may not be safe during these times.

Discuss your medical history with your healthcare provider to ensure DAIVOBET Ointment is appropriate for your condition.

Storage of DAIVOBET

Storage instructions for DAIVOBET Ointment:

• Store DAIVOBET Ointment at room temperature, between 20°C to 25°C (68°F to 77°F), away from direct light and moisture.
• Keep the ointment in its original collapsible tube, tightly closed, to protect it from contamination and maintain its effectiveness.
• Avoid storing DAIVOBET in the bathroom or other humid areas where temperature fluctuations and moisture may compromise the ointment’s quality.
• Keep the medication out of reach of children and pets to prevent accidental ingestion or misuse.
• Do not use the ointment after the expiration date printed on the packaging. Dispose of any unused or expired medication according to local regulations for safe disposal of pharmaceuticals.

If you have any questions regarding the storage or handling of DAIVOBET Ointment, consult your pharmacist or healthcare provider for guidance.