DAIVOBET Ointment

What is DAIVOBET

DAIVOBET Ointment (30g) is a combination medication used to treat psoriasis, a chronic autoimmune skin condition characterized by rapid skin cell growth that leads to scaling, redness, and inflammation. The active ingredients in DAIVOBET are calcipotriol and betamethasone dipropionate. Calcipotriol is a synthetic form of vitamin D3, which helps to regulate the production of skin cells, slowing down their overgrowth, a key issue in psoriasis. Betamethasone, on the other hand, is a potent corticosteroid that works by reducing inflammation, itching, and redness associated with the condition. The ointment provides symptomatic relief and improves the appearance of psoriasis plaques by reducing flaking and skin build-up.

DAIVOBET Ointment is particularly effective in the treatment of plaque psoriasis, which is the most common form of the disease. Plaque psoriasis appears as raised, red patches covered with a silvery-white build-up of dead skin cells. The dual-action of calcipotriol and betamethasone in DAIVOBET is designed to both manage the immediate symptoms and address the underlying skin cell production issues.

This formulation comes in a 30g collapsible tube, and it is for external use only. It should not be applied to the face, underarms, or groin area unless specifically directed by a healthcare provider. Proper and consistent use of DAIVOBET Ointment can significantly improve the quality of life for individuals with psoriasis by minimizing flare-ups and providing relief from the itching and discomfort associated with the condition.

How to use DAIVOBET

The application and usage instructions for DAIVOBET Ointment are crucial for ensuring its effectiveness and minimizing side effects. DAIVOBET Ointment should be applied exactly as prescribed by your healthcare provider. Typically, it is applied to the affected areas of the skin once daily, preferably in the evening. It is important to apply a thin layer of the ointment to the areas affected by psoriasis, gently rubbing it into the skin until it is fully absorbed. Avoid using it on healthy skin to prevent unwanted side effects.

The ointment is for external use only and should not be used on broken or infected skin unless specifically directed by a healthcare professional. If applying it to areas of skin that may come into contact with clothing, ensure the ointment has fully absorbed to avoid transferring it to fabric.

After applying the ointment, wash your hands thoroughly to avoid accidentally spreading it to other areas, especially the face, mouth, or eyes. If the product gets into your eyes, rinse thoroughly with water. The total amount of ointment used in a week should not exceed 100 grams to avoid potential systemic side effects related to corticosteroids and calcipotriol.

Do not cover the treated areas with bandages or other coverings unless instructed by your doctor, as this can increase the absorption of the medication and raise the risk of side effects. Regular follow-up with your healthcare provider is recommended to monitor your condition and ensure the medication is working effectively without adverse effects.

Mode of Action DAIVOBET

DAIVOBET Ointment contains two active ingredients that work together to manage psoriasis symptoms. Calcipotriol is a vitamin D3 analogue, which means it mimics the action of vitamin D in the skin. Vitamin D is essential for skin cell development and regulation. In individuals with psoriasis, skin cells grow too quickly, leading to the formation of thick, scaly patches. Calcipotriol helps to slow this excessive skin cell growth, reducing the thickening and scaling of the skin. It also helps to improve the overall texture of the skin by promoting more normal skin cell turnover.

Betamethasone dipropionate is a potent corticosteroid that reduces inflammation, swelling, and itching. Psoriasis is not only characterized by the rapid turnover of skin cells but also by inflammation that leads to the redness and irritation of the affected areas. Betamethasone works by suppressing the immune response that causes inflammation in the skin, providing relief from the uncomfortable symptoms of psoriasis.

The combination of these two ingredients allows DAIVOBET to address both the excessive production of skin cells and the inflammatory response, making it a highly effective treatment for plaque psoriasis. By reducing both the scaling and the inflammation, DAIVOBET helps to improve the appearance of the skin and relieve the discomfort associated with the condition.

It is important to note that while DAIVOBET can effectively manage the symptoms of psoriasis, it is not a cure for the condition. Psoriasis is a chronic disease that may require ongoing treatment and lifestyle management to control flare-ups.

DAIVOBET Interactions DAIVOBET

As with many medications, DAIVOBET Ointment can interact with other treatments or drugs, potentially altering its effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider of all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and topical treatments.

Corticosteroids like betamethasone can have systemic effects, especially when used over large areas of the body or for extended periods. Therefore, the use of other corticosteroid medications, whether topical or systemic, should be discussed with your doctor to avoid excessive corticosteroid exposure. Additionally, vitamin D analogues, such as calcipotriol, may also interact with other vitamin D supplements or treatments, potentially leading to an increased risk of side effects such as hypercalcemia (elevated calcium levels in the blood).

Topical treatments applied to the same area of the skin can interact with each other, so it is essential to avoid using other creams, ointments, or lotions on the affected areas unless specifically recommended by your healthcare provider. Furthermore, some medications, such as those used to treat certain skin conditions, may interfere with the absorption of DAIVOBET, reducing its effectiveness.

If you are using any form of phototherapy (light therapy) for psoriasis, inform your healthcare provider, as the combination of light therapy and DAIVOBET may require special precautions to avoid overexposure to ultraviolet light. Always follow your healthcare provider’s advice regarding the use of DAIVOBET in combination with other treatments.

Dosage of DAIVOBET

The dosage of DAIVOBET Ointment is individualized based on the severity of the psoriasis and the areas of the body affected. Typically, the ointment is applied once daily to the affected areas of the skin. The total dose applied to the skin should not exceed 100 grams per week, as excessive use can lead to increased absorption of the active ingredients and a higher risk of side effects, particularly those associated with corticosteroids.

To apply, squeeze a small amount of the ointment onto your fingertip and spread it over the psoriasis plaques. Rub the ointment into the skin gently until it is fully absorbed. It is important to apply the medication consistently and at the same time each day to maintain its effectiveness.

For most patients, visible improvement in the symptoms of psoriasis is seen within 2 weeks of treatment, but the full effects may take longer to achieve. Continue to use the ointment for the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before the treatment is completed. If you miss a dose, apply it as soon as you remember, but do not apply more than the recommended amount to make up for a missed dose.

Your healthcare provider may adjust your dose based on your response to treatment and the severity of side effects, if any. It is important to have regular follow-up appointments to assess your progress and make any necessary adjustments to the treatment plan.

Possible side effects of DAIVOBET

Like all medications, DAIVOBET Ointment can cause side effects, although not everyone will experience them. The most common side effects are related to skin irritation and include:

• Itching or burning sensation at the application site
• Redness or rash
• Dry skin or peeling

These side effects are usually mild and temporary, resolving as your skin adjusts to the medication. However, if these symptoms persist or worsen, contact your healthcare provider.

More serious side effects are rare but can occur, especially with prolonged use or application over large areas of the body. These may include:

• Thinning of the skin (atrophy)
• Stretch marks (striae)
• Increased hair growth
• Changes in skin color (hypopigmentation or hyperpigmentation)

Long-term use of corticosteroids, such as betamethasone, can lead to systemic effects, particularly when used in high doses or on large areas of the skin. These systemic effects can include:

• Suppression of adrenal gland function
• Increased risk of infection
• High blood sugar levels
• Osteoporosis (weakened bones)

These effects are more likely to occur with prolonged or excessive use, so it is important to use DAIVOBET exactly as prescribed by your healthcare provider and to attend regular follow-up appointments to monitor for any signs of side effects.

DAIVOBET Contraindications DAIVOBET

Information not available.

Storage of DAIVOBET

To maintain the effectiveness of DAIVOBET Ointment, it is important to store it properly:

• Keep the ointment in its original packaging until ready for use to protect it from light and moisture.
• Store at room temperature (below 25°C), away from direct heat and sunlight.
• Do not freeze the product, as extreme temperatures can affect its stability.

Always keep DAIVOBET Ointment out of the reach of children and pets to avoid accidental ingestion or application. If the product is accidentally swallowed, seek medical attention immediately.

Do not use DAIVOBET after the expiration date printed on the packaging. Expired medication may not be effective and could potentially cause harm.

If you are unsure about how to dispose of unused or expired DAIVOBET Ointment, consult your pharmacist or local waste disposal authority for proper disposal guidelines.