DAIVOBET Gel

What is DAIVOBET

DAIVOBET is a topical dermatological gel formulated with two active ingredients: Adapalene 0.1% and Benzoyl Peroxide 2.5%. This combination therapy is designed primarily to treat moderate to severe acne vulgaris. Adapalene, a third-generation synthetic retinoid, modulates skin cell differentiation and inflammation, while Benzoyl Peroxide acts as an antimicrobial agent that reduces the bacterial load on the skin. DAIVOBET is available in a 60g HDPE bottle, offering a user-friendly and hygienic application for daily use.

• Generic Names: Adapalene 0.1%, Benzoyl Peroxide 2.5%
• Form: Topical Gel
• Main Indication: Treatment of acne vulgaris, especially inflammatory lesions such as papules and pustules.

This dual-action formulation is particularly effective for patients seeking fast, comprehensive acne management without systemic exposure.

How to use DAIVOBET

Proper application of DAIVOBET enhances its effectiveness while minimizing the risk of irritation:

• Preparation: Cleanse the skin with a mild, non-irritating cleanser and pat dry completely before application.
• Application: Apply a thin layer of the gel to the entire affected area once daily, preferably in the evening before bedtime.
• Amount: A pea-sized amount is sufficient for the entire face. Avoid the eyes, lips, and mucous membranes.
• Post-Application: Wash hands thoroughly after applying the medication.
• Sun Exposure: Use sunscreen and protective clothing to prevent photosensitivity reactions.

Continue using DAIVOBET as directed by your healthcare provider, even if acne initially worsens, as this is often a sign that the medication is working to clear clogged pores.

Mode of Action DAIVOBET

DAIVOBET works through a synergistic mechanism that targets multiple aspects of acne pathophysiology:

• Adapalene Action: Modulates keratinization and cell turnover to prevent the formation of microcomedones. It also exhibits anti-inflammatory properties by inhibiting inflammatory mediators.
• Benzoyl Peroxide Action: Acts as a potent antibacterial agent against Propionibacterium acnes, the bacteria implicated in acne development. It also has keratolytic properties that help in removing dead skin cells and unclogging pores.
• Combined Effect: Reduces both non-inflammatory and inflammatory acne lesions efficiently by targeting bacterial proliferation, clogged pores, and skin inflammation simultaneously.

This dual-action approach provides a faster onset of action and greater efficacy compared to monotherapy treatments.

DAIVOBET Interactions DAIVOBET

Certain interactions should be considered when using DAIVOBET:

• Other Topical Retinoids: Concurrent use with other retinoids can increase the risk of skin irritation and dryness.
• Photosensitizing Agents: Use with drugs that increase sensitivity to sunlight (such as tetracyclines or thiazides) can enhance photosensitive reactions.
• Abrasive Skincare Products: Products containing alcohol, astringents, or exfoliants may exacerbate local skin irritation.
• Topical Antibiotics: Using topical clindamycin or erythromycin along with DAIVOBET should be monitored to avoid excessive irritation, though no severe pharmacological interaction is known.

Always inform your healthcare provider of all topical and oral medications you are using to avoid adverse interactions.

Dosage of DAIVOBET

Adhering to the correct dosage guidelines is vital for safe and effective treatment:

• Standard Adult Dose: Apply a thin layer once daily to the affected areas after cleansing.
• Special Populations: Use in pediatric patients over 12 years should be supervised by a healthcare provider. Use in pregnant or breastfeeding women should be avoided unless absolutely necessary.
• Missed Dose: If a dose is missed, apply it as soon as remembered unless it is almost time for the next scheduled dose. Do not double the dose.
• Overuse Warning: Applying larger amounts or using more frequently than prescribed will not improve results and may increase irritation.

It’s important to follow your doctor’s instructions precisely to maximize benefits while minimizing risks.

Possible side effects of DAIVOBET

DAIVOBET is generally well-tolerated but can cause side effects, especially during the initial phase of treatment:

• Common Side Effects: Dryness, redness, scaling, burning sensation, or stinging at the site of application.
• Less Common Side Effects: Skin peeling, erythema (skin redness), and slight swelling.
• Rare Adverse Effects: Severe allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Photosensitivity: Increased risk of sunburn; users are advised to take sun protection measures.

Side effects often lessen with continued use. If severe irritation or allergic reaction occurs, discontinue use and seek medical attention promptly.

DAIVOBET Contraindications DAIVOBET

DAIVOBET is generally well-tolerated but can cause side effects, especially during the initial phase of treatment:

• Common Side Effects: Dryness, redness, scaling, burning sensation, or stinging at the site of application.
• Less Common Side Effects: Skin peeling, erythema (skin redness), and slight swelling.
• Rare Adverse Effects: Severe allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Photosensitivity: Increased risk of sunburn; users are advised to take sun protection measures.

Side effects often lessen with continued use. If severe irritation or allergic reaction occurs, discontinue use and seek medical attention promptly.

Storage of DAIVOBET

Proper storage of DAIVOBET ensures the stability and efficacy of the product:

• Temperature: Store at 20°C to 25°C (68°F to 77°F); excursions between 15°C and 30°C are permissible.
• Light Sensitivity: Keep the product away from direct sunlight and extreme heat.
• Container Care: Ensure the bottle cap is tightly closed after each use to prevent contamination and drying out.
• Expiration: Discard the product after the expiration date or if there are any changes in color, consistency, or smell.
• Keep Out of Reach: Store safely out of reach of children and pets.

Following these storage guidelines helps to maintain product quality throughout its shelf life.