EVISTA 60mg Price

Overview

Welcome to Dwaey, specifically on EVISTA 60mg page.
This medicine contains an important and useful components, as it consists of
Raloxifene HClis available in the market in concentration

Name

Raloxifene Hydrochloride

Precaution

Women w/ risk factors for venous thromboembolism including CHF or active malignancy, risk factors for stroke (e.g. TIA, AF), history of oestrogen-induced hypertriglyceridaemia. Moderate renal impairment. Monitoring Parameters Monitor serum triglyceride concentration. Lactation: Excretion in milk unknown; contraindicated

Indication

Post-menopausal osteoporosis, Malignant gastrointestinal stromal tumours, Prevention & risk reduction of invasive breast cancer

Contra indication

Active or history of venous thromboembolic events including DVT, pulmonary embolism, retinal vein thrombosis. Unexplained uterine bleeding. Patients w/ signs/symptoms of endometrial cancer. Hepatic (including cholestasis) and severe renal impairment. Pregnancy, women who may become pregnant, and lactation.

Side Effect

>10% Hot flashes (8-29%),Flu syndrome (14-15%),Cramps/muscle spasm (6-12%),Arthralgia (11-16%),Infection (11%) 1-10% Insomnia (6%),Vomiting (5%),Sinusitis (10%),Venous thromboembolism (1-2% ),Bronchitis (10%),Pharyngitis (8%),Breast pain (4%),Gastroenteritis (<3%),Diaphoresis (3%) Frequency Not Defined Deep vein thrombosis,Cerebrovascular accident,Thrombosis of retinal vein (rare),Pulmonary embolism,Decreased fibrinogen

Pregnancy Category ID

5

Mode of Action

Raloxifene is a selective oestrogen receptor modulator that has both selective agonist or antagonist activities on oestrogen receptors. It acts as an agonist on bone by preventing bone loss and partially on cholesterol metabolism by decreasing total and LDL cholesterol levels but antagonises oestrogen effects leading to development of breast and uterine cancer.

Interaction

Cholestyramine reduces the absorption of raloxifene. Raloxifene with warfarin may reduce the prothrombin response and time. Caution when used in hghly protein-bound drugs such as diazepam, lidocaine and diazoxide.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration