Overview Of Anal fissure
An anal fissure is a small tear or crack in the skin lining the anus, typically causing pain and discomfort during or after bowel movements. These tears can occur as a result of trauma to the anal canal, often due to the passage of hard stools, chronic constipation, or prolonged diarrhea. Anal fissures can also be associated with other conditions such as inflammatory bowel disease, or they can occur without an underlying disease. While anal fissures are common and typically heal on their own with conservative treatment, some individuals may experience recurring or chronic fissures that require medical intervention. The primary symptoms of an anal fissure include sharp pain during bowel movements, blood in the stool, and itching or irritation around the anus. Though not a life-threatening condition, anal fissures can significantly impact quality of life, particularly when they cause persistent pain or discomfort.
Symptoms of Anal fissure
- The symptoms of an anal fissure can vary in severity, depending on whether the fissure is acute (recently developed) or chronic (long-standing). Common symptoms include: - Pain during or after bowel movements: The most characteristic symptom of an anal fissure is sharp pain during and after passing stool, particularly with hard stools. The pain can last for minutes to hours after a bowel movement. - Bleeding: The fissure can cause slight bleeding, often noticed as bright red blood on toilet paper or in the toilet bowl after a bowel movement. - Itching and irritation: The area around the anus may become irritated or itchy, especially if the fissure is chronic. - Visible tear or crack: In some cases, the fissure can be visible as a small tear or crack in the skin around the anus, especially in acute fissures. - Spasms of the anal sphincter: Anal sphincter spasms can occur due to pain, making bowel movements even more difficult and painful. This can contribute to a cycle of pain and further trauma to the area. - Fissure tags: In chronic fissures, skin growths (called fissure tags) may develop around the tear. These can be seen as small, puffy bumps of skin near the anus.
Causes of Anal fissure
- The primary cause of an anal fissure is trauma to the skin of the anus, which can be caused by: - Hard stools or constipation: Straining during bowel movements, often due to constipation or the passage of large, hard stools, is one of the most common causes of anal fissures. The force required to pass these stools can cause the delicate skin in the anus to tear. - Chronic diarrhea: Frequent bowel movements or diarrhea can irritate the anal canal and increase the likelihood of developing fissures. - Childbirth: The pressure exerted during vaginal delivery can cause tears in the anal canal, especially if there is significant stretching or trauma during the delivery process. - Inflammatory bowel disease (IBD): Conditions such as Crohn’s disease or ulcerative colitis, which cause chronic inflammation in the gastrointestinal tract, can increase the risk of developing anal fissures. - Anal intercourse: Traumatic injury during anal sex can result in the development of fissures in the anal skin. - Other contributing factors: Conditions that affect bowel movements, such as neurological disorders that cause impaired sphincter control or reduced blood flow to the area, can contribute to the development of anal fissures.
Risk Factors of Anal fissure
- Certain factors can increase the risk of developing an anal fissure, including: - Chronic constipation: Straining to pass hard stools is one of the leading risk factors for anal fissures. Consistently difficult bowel movements can put excessive pressure on the anal canal. - Diarrhea: Chronic diarrhea can irritate the sensitive skin of the anus and lead to fissures. - Pregnancy and childbirth: The physical stress of childbirth, particularly vaginal delivery, can stretch and tear the anal skin. Pregnancy can also lead to constipation, which is another risk factor. - Inflammatory bowel disease (IBD): People with IBD, such as Crohn’s disease and ulcerative colitis, are at higher risk for developing anal fissures due to the inflammation and irritation in the digestive tract. - Age: Older adults tend to experience more frequent constipation, which increases the likelihood of developing anal fissures. - Poor diet: A diet low in fiber can lead to constipation and harder stools, raising the risk of anal fissures. - Anal intercourse: This can cause direct trauma to the anal region, increasing the risk of fissures. - Impaired anal sphincter tone: Conditions that affect the muscles of the anus, such as neurological disorders or surgeries affecting the rectal area, may increase the risk of fissures.
Prevention of Anal fissure
- Preventing anal fissures involves addressing the risk factors that contribute to their development: - Maintain a high-fiber diet: Eating plenty of fruits, vegetables, and whole grains can help prevent constipation and soften stools, making bowel movements less painful. - Stay hydrated: Drinking enough water each day helps keep stools soft and easy to pass. - Avoid straining: Try not to strain during bowel movements. If constipation is a problem, consider using stool softeners or laxatives as directed by a healthcare provider. - Practice good hygiene: Keep the anal area clean but avoid harsh wiping, as it can irritate the skin. Instead, consider using moist wipes or taking a warm sitz bath after bowel movements. - Regular exercise: Physical activity can help regulate bowel movements and reduce the likelihood of constipation.
Prognosis of Anal fissure
- The prognosis for anal fissures is generally very good, particularly in cases where the fissures are acute and treated early. Most acute anal fissures heal within a few weeks with proper treatment, including dietary changes and topical medications. However, chronic or recurrent anal fissures, especially those associated with conditions such as inflammatory bowel disease or neurological disorders, may require more intensive treatment and can have a prolonged healing period. In cases where surgical intervention is necessary, healing can take several weeks, and there is a small risk of complications, such as infection or incontinence, although these are rare. If treated appropriately, most individuals can expect complete resolution of symptoms and healing of the fissure.
Complications of Anal fissure
- Although anal fissures generally heal without long-term issues, there can be complications if the condition is not adequately managed: - Chronic fissures: If an anal fissure does not heal within a few weeks and becomes chronic, it may require surgical treatment, such as sphincterotomy. - Infection: Like any open wound, anal fissures can become infected, especially if hygiene is not maintained or if the fissure is large or deep. - Anal fistula: In some cases, an anal fissure may develop into an anal fistula, which is an abnormal tunnel between the anal canal and the skin, leading to recurrent infections or abscesses. - Incontinence: Although rare, surgery to treat a chronic anal fissure may result in complications such as bowel incontinence or changes in anal sphincter function. - Recurrence: Even after successful treatment, anal fissures can recur, particularly in individuals who continue to experience constipation or other underlying conditions.
Related Diseases of Anal fissure
- Several conditions are related to or share similarities with anal fissures: - Hemorrhoids: Like anal fissures, hemorrhoids can cause pain, bleeding, and discomfort around the anus, though hemorrhoids involve swollen veins rather than tears in the skin. - Anal abscess: An abscess can form near the anus, often as a result of an infection, and may present with symptoms similar to those of an anal fissure, including pain and swelling. - Anal fistula: An anal fistula is an abnormal connection between the anal canal and the skin around the anus, which can develop from an untreated anal abscess or fissure. - Crohn’s disease: This inflammatory bowel disease can cause chronic anal fissures due to the underlying inflammation in the gastrointestinal tract. - Ulcerative colitis: Another form of inflammatory bowel disease, ulcerative colitis can cause similar symptoms to Crohn’s disease, including anal fissures.
Treatment of Anal fissure
The treatment for anal fissures depends on whether the condition is acute or chronic and typically involves conservative measures to promote healing and alleviate symptoms. Treatment options include: - **Dietary changes**: Increasing fiber intake and drinking plenty of water can help prevent constipation, making stools softer and easier to pass, which can reduce strain on the anal area. - **Topical treatments**: - **Stool softeners**: Medications such as stool softeners or laxatives can be used to prevent constipation and make bowel movements easier. - **Topical nitroglycerin**: A prescription medication that helps relax the anal sphincter, allowing the fissure to heal more easily by increasing blood flow to the area. - **Topical hydrocortisone**: Creams or ointments that reduce inflammation and itching, though these are used cautiously as they may affect healing if used long-term. - **Calcium channel blockers**: Topical medications, such as nifedipine, can also be used to relax the anal sphincter and promote healing. - **Warm sitz baths**: Soaking the anal area in warm water several times a day can help reduce pain, relieve muscle spasms, and promote healing of the fissure. - **Pain management**: Over-the-counter pain relievers, such as ibuprofen or acetaminophen, can help alleviate pain. In some cases, topical anesthetics may be used to numb the area temporarily. - **Botox injections**: In cases of chronic anal fissures, botulinum toxin (Botox) injections can be used to relax the anal sphincter and reduce spasms, which allows the fissure to heal more effectively. - **Surgical intervention**: If the fissure does not heal with conservative measures and becomes chronic, surgery may be required. The most common procedure is **lateral internal sphincterotomy**, which involves cutting a small portion of the anal sphincter muscle to reduce spasms and promote healing.
Generics For Anal fissure
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Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep)
Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep)

Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep
Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep

Lidocaine Hydrochloride 2%, 10%
Lidocaine Hydrochloride 2%, 10%

Hydrocortisone + Lidocaine rectal prep
Hydrocortisone + Lidocaine rectal prep

Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep)
Cinchocaine Hydrochloride 0.5% + Esculin 1% + Hydrocortisone + Neomycin Sulphate (Rectal prep)

Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep
Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep

Lidocaine Hydrochloride 2%, 10%
Lidocaine Hydrochloride 2%, 10%

Hydrocortisone + Lidocaine rectal prep
Hydrocortisone + Lidocaine rectal prep