AMRIZOLE 250mg Tablets

What is AMRIZOLE 250mg

What is AMRIZOLE 250mg: AMRIZOLE 250mg is a tablet formulation containing Metronidazole, an antibiotic and antiprotozoal agent. It is used to treat various infections caused by anaerobic bacteria and protozoa, including infections of the gastrointestinal tract, skin, joints, respiratory system, and reproductive organs.

How to use AMRIZOLE 250mg

How to use AMRIZOLE 250mg: AMRIZOLE 250mg should be taken orally, exactly as prescribed by the doctor. It can be taken with or without food, but taking it with food may help reduce stomach upset. Tablets should be swallowed whole with water, and the full course must be completed even if symptoms improve.

Mode of Action AMRIZOLE 250mg

Mode of action of AMRIZOLE 250mg: Metronidazole enters microbial cells and disrupts their DNA structure by forming free radicals, inhibiting nucleic acid synthesis. This leads to the death of anaerobic bacteria and protozoa, effectively eliminating the infection.

AMRIZOLE 250mg Interactions AMRIZOLE 250mg

Interactions of AMRIZOLE 250mg: AMRIZOLE 250mg can interact with anticoagulants like warfarin (increasing bleeding risk), alcohol (causing disulfiram-like reactions), and medications like cimetidine (which may increase metronidazole levels). It may also reduce the effectiveness of certain drugs like phenytoin and phenobarbital.

Dosage of AMRIZOLE 250mg

Dosage of AMRIZOLE 250mg: The usual adult dose ranges from 500mg to 750mg every 8 hours, depending on the infection being treated. In some cases, lower doses may be prescribed. Dosage adjustments are needed in patients with liver impairment or severe renal dysfunction, based on medical evaluation.

Possible side effects of AMRIZOLE 250mg

Possible side effects of AMRIZOLE 250mg: Common side effects include nausea, a metallic taste, diarrhea, abdominal cramping, and dizziness. Less common but serious side effects can include peripheral neuropathy, seizures, and severe allergic reactions requiring immediate medical attention.

AMRIZOLE 250mg Contraindications AMRIZOLE 250mg

Contraindications of AMRIZOLE 250mg: AMRIZOLE 250mg is contraindicated in patients with known hypersensitivity to metronidazole or nitroimidazole derivatives. It should be avoided during the first trimester of pregnancy unless absolutely necessary and used with caution in patients with neurological disorders.

Storage of AMRIZOLE 250mg

Storage of AMRIZOLE 250mg: AMRIZOLE 250mg should be stored at room temperature, away from moisture, heat, and direct sunlight. Tablets should remain in their original packaging and kept out of the reach of children. Expired or unused tablets should be properly discarded.