Panadrex MAX Tablet

What is Panadrex MAX

Panadrex MAX is a dual-ingredient analgesic and antipyretic medication formulated in tablet form. It contains:

• Paracetamol (Acetaminophen): A widely used pain reliever and fever reducer.
• Caffeine: A mild stimulant that enhances the efficacy of paracetamol and helps reduce fatigue associated with pain.

This formulation is particularly effective for the relief of moderate to severe pain, especially when rapid and enhanced relief is desired. It is commonly used for:

• Headaches, including tension headaches and migraines
• Toothaches and dental pain
• Muscle aches and back pain
• Menstrual cramps
• Fever associated with cold or flu

Panadrex MAX is typically packaged in a blister pack of 48 tablets, making it convenient for longer-term or household use.

How to use Panadrex MAX

It is important to use Panadrex MAX exactly as directed to avoid overdose or reduced effectiveness. Consider the following guidelines:

• Adults and children over 12 years: Take 1–2 tablets every 4 to 6 hours as needed.
• Maximum dose: Do not exceed 8 tablets in 24 hours.
• Swallow whole: Take tablets with a full glass of water. Do not crush or chew.
• With or without food: Can be taken regardless of meals, but food may help prevent stomach upset.
• Do not combine with other paracetamol-containing products to avoid overdose.

Always consult your pharmacist or healthcare provider if you are unsure about the correct dosage or timing. If symptoms persist for more than a few days, seek medical advice.

Mode of Action Panadrex MAX

Panadrex MAX works through a synergistic combination of paracetamol and caffeine:

• Paracetamol:
  • Acts primarily in the central nervous system by inhibiting the enzyme cyclooxygenase (COX), which reduces the production of prostaglandins—compounds that mediate pain and fever.
  • Has a weak anti-inflammatory action but is highly effective in reducing pain and fever.
• Caffeine:
  • Stimulates the central nervous system to counteract fatigue and improve mental alertness.
  • Enhances the analgesic effect of paracetamol, making pain relief faster and more effective.
  • May help narrow dilated blood vessels in the brain, offering added benefit for headache relief, especially in migraines.

The combined action results in more potent and sustained pain relief, particularly useful in conditions where tiredness exacerbates discomfort.

Panadrex MAX Interactions Panadrex MAX

It is important to be aware of potential interactions with Panadrex MAX due to its two active ingredients:

• Alcohol: Increases the risk of liver damage when taken with paracetamol.
• Other Paracetamol-containing drugs: Risk of overdose and liver toxicity—always check labels before combining products.
• Anticoagulants (e.g., warfarin): Chronic use of paracetamol may enhance the effect of blood thinners.
• MAO Inhibitors or other stimulants: Caffeine may interact with antidepressants and other CNS stimulants, increasing the risk of high blood pressure or arrhythmias.
• Anticonvulsants and rifampin: May reduce the effectiveness of paracetamol by accelerating liver metabolism.
• Beta-blockers: Caffeine can reduce the antihypertensive effects of certain blood pressure medications.

Always inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting Panadrex MAX.

Dosage of Panadrex MAX

Correct dosing is essential to maximize efficacy and minimize risk:

• Adults and adolescents over 12 years:
  • Take 1–2 tablets every 4 to 6 hours as needed.
  • Do not exceed 8 tablets in a 24-hour period.
• Children under 12 years: Not recommended without medical advice.
• Use for limited periods: If pain persists for more than 3 days or fever for more than 2 days, consult a doctor.

Note: Avoid combining with other medications containing paracetamol. Do not use for extended durations unless directed by a healthcare provider.

Possible side effects of Panadrex MAX

While generally well-tolerated, Panadrex MAX may cause side effects in some individuals:

• Common side effects:
  • Nausea or stomach discomfort
  • Restlessness or mild insomnia (due to caffeine)
  • Headache (paradoxically, with overuse)
• Less common side effects:
  • Increased heart rate or palpitations (from caffeine)
  • Allergic skin reactions such as rash or itching
• Rare but serious effects:
  • Liver toxicity, especially with overdose or alcohol use
  • Severe allergic reactions like angioedema or anaphylaxis
  • Blood disorders (e.g., thrombocytopenia, leukopenia)

If any severe reaction occurs, discontinue use and seek immediate medical attention. Always adhere to the recommended dosage.

Panadrex MAX Contraindications Panadrex MAX

Do not use Panadrex MAX in the following situations:

• Allergy to paracetamol or caffeine or any other component of the formulation
• Severe liver impairment or active liver disease
• History of caffeine sensitivity such as insomnia, palpitations, or tremors
• Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping them
• Pregnancy and breastfeeding: Use with caution and only under medical supervision
• Children under 12 years: Not suitable due to caffeine content

Always consult a healthcare provider if you are unsure whether Panadrex MAX is safe for your condition.

Storage of Panadrex MAX

To ensure the effectiveness and safety of Panadrex MAX, follow these storage recommendations:

• Store below 25°C (77°F): Keep in a cool, dry place away from heat and moisture.
• Keep in original packaging: Protect tablets from light and humidity by storing them in their blister pack.
• Keep out of reach of children: Accidental ingestion by children may be harmful or fatal.
• Do not use after expiration date: Always check the label for expiry before use.
• Do not refrigerate or freeze: Room temperature storage is ideal.

Proper storage helps preserve the integrity of the medication and ensures safe use throughout its shelf life.