OXYNORM 20mg Capsules (Hard Gelatin)

What is OXYNORM 20mg

OXYNORM 20mg is a strong opioid analgesic containing Oxycodone Hydrochloride, used to manage moderate to severe pain where other painkillers are insufficient. It is provided as hard gelatin capsules designed for immediate-release action, making it suitable for breakthrough or acute pain episodes.

• Generic Name: Oxycodone Hydrochloride
• Form: Hard gelatin capsules
• Strength: 20mg of oxycodone HCl per capsule
• Pack Size: 56 capsules (14s blister x 4)
• Therapeutic Class: Opioid Analgesic

This formulation acts quickly to relieve pain, commonly used in cancer-related pain, post-operative pain, and chronic pain conditions that require short-term opioid therapy.

How to use OXYNORM 20mg

OXYNORM capsules are designed for oral use and should be taken exactly as prescribed by your doctor.

• Swallow whole with water; do not crush or chew.
• Can be taken with or without food, but consistency is important for stable absorption.
• Usually administered every 4–6 hours depending on pain severity and patient tolerance.
• Avoid alcohol as it may increase the risk of serious side effects like respiratory depression.
• Missed dose: Take as soon as remembered unless it is almost time for the next dose. Do not double the dose.

Patients should not stop taking OXYNORM suddenly without consulting their doctor, as this can lead to withdrawal symptoms. Tapering may be necessary if discontinuing therapy.

Mode of Action OXYNORM 20mg

Oxycodone is a semi-synthetic opioid that exerts its effects by binding to μ-opioid receptors in the central nervous system (CNS).

• Analgesic Effect: Reduces pain perception by altering transmission of pain signals in the spinal cord and brain.
• CNS Depressant: Induces sedation and euphoria by dampening CNS activity.
• Onset: Rapid absorption allows for fast pain relief (within 30 minutes).
• Duration: Short-acting; effective for 3–6 hours.

Oxycodone mimics endogenous endorphins, enhancing pain threshold and reducing emotional responses to pain.

OXYNORM 20mg Interactions OXYNORM 20mg

OXYNORM may interact with a variety of medications and substances, potentially leading to adverse effects or diminished efficacy.

• CNS depressants (e.g., benzodiazepines, alcohol, antipsychotics): Increased risk of respiratory depression and sedation.
• MAO inhibitors: Avoid co-administration within 14 days due to risk of serotonin syndrome or CNS toxicity.
• SSRIs/SNRIs (e.g., fluoxetine, venlafaxine): May increase risk of serotonin syndrome.
• Cytochrome P450 inhibitors (e.g., ketoconazole, erythromycin): May raise oxycodone blood levels, increasing toxicity risk.
• Inducers (e.g., rifampin, carbamazepine): Can decrease plasma levels, reducing analgesic effect.
• Anticholinergics: May increase risk of urinary retention and constipation.

Always inform your healthcare provider of all medications, supplements, and herbs you are taking.

Dosage of OXYNORM 20mg

Dosage should be individualized based on the severity of pain, patient condition, and previous opioid exposure.

• Adults: Typically 5 to 20 mg every 4–6 hours. OXYNORM 20mg may be used for opioid-tolerant patients requiring higher doses.
• Maximum Daily Dose: There is no absolute maximum, but dose titration should be done cautiously to avoid overdose.
• Elderly or renal/hepatic impairment: Start at the lower end of the dosage range with close monitoring.
• Pediatric Use: Not recommended unless explicitly directed by a specialist.

Frequent re-evaluation is necessary to determine if dosage adjustments are required for optimal pain control with minimal adverse effects.

Possible side effects of OXYNORM 20mg

While effective for pain relief, OXYNORM may cause side effects, particularly with prolonged use.

• Common: Nausea, constipation, drowsiness, dry mouth, dizziness.
• Serious: Respiratory depression, hypotension, seizures, addiction/dependence.
• Psychiatric: Mood changes, confusion, hallucinations (especially in elderly).
• Allergic reactions: Rash, itching, swelling, breathing difficulties (seek immediate care).
• Long-term risks: Tolerance, physical dependence, adrenal suppression, hormonal imbalance.

Promptly report any severe or unusual reactions to your healthcare provider. Regular monitoring is crucial for safe opioid use.

OXYNORM 20mg Contraindications OXYNORM 20mg

OXYNORM should not be used in certain patient populations due to risk of severe adverse reactions.

• Known hypersensitivity to oxycodone or other opioids.
• Severe respiratory depression or bronchial asthma in unmonitored settings.
• Paralytic ileus or other gastrointestinal obstruction.
• Acute or severe liver impairment, as metabolism of the drug is reduced.
• Pregnancy: Avoid use unless absolutely necessary; risk of neonatal withdrawal.
• Concurrent MAOI use or within 14 days of discontinuation.

Use with extreme caution in individuals with history of substance abuse, mental health disorders, or impaired respiratory function.

Storage of OXYNORM 20mg

Proper storage of opioid medications is essential to maintain drug efficacy and avoid misuse or accidental ingestion.

• Temperature: Store below 25°C (77°F) in a cool, dry place.
• Light and Moisture: Protect from direct sunlight and humidity. Keep in original packaging.
• Child Safety: Store in a locked cabinet out of reach of children and pets.
• Do not use beyond the expiry date on the blister pack.
• Disposal: Return unused or expired capsules to a pharmacy. Do not flush down the toilet.

Improper storage or disposal can lead to accidental overdose, poisoning, or environmental contamination.