What is ALGOXIB 200mg
ALGOXIB 200 mg is an oral capsule containing **celecoxib**, a COX‑2‑selective NSAID. It is available in hard gelatin capsules (30-count packs: 3×10 blisters).
- Pharmacologic class: Selective cyclooxygenase‑2 inhibitor, designed to reduce inflammation and pain while sparing COX‑1–preserved gastric protection :contentReference[oaicite:1]{index=1}.
- Indications:
- Osteoarthritis, rheumatoid arthritis
- Ankylosing spondylitis
- Acute pain, primary dysmenorrhea, migraine attacks
- Juvenile rheumatoid arthritis (≥ 2 years old) :contentReference[oaicite:2]{index=2}.
- Benefits: Eases pain and swelling, typically within 1–2 hours, with reduced gastrointestinal side effects compared to traditional NSAIDs :contentReference[oaicite:3]{index=3}.
- Limitations: Does not treat underlying disease; long-term use carries cardiovascular and GI risks :contentReference[oaicite:4]{index=4}.
How to use ALGOXIB 200mg
Administer ALGOXIB under medical guidance to ensure efficacy and safety.
- Dosage forms: Swallow capsule whole with water; may open capsule and sprinkle on applesauce if needed :contentReference[oaicite:5]{index=5}.
- Timing: Take with or without food; high‑fat meals may delay absorption by ~1 hour without lowering effectiveness :contentReference[oaicite:6]{index=6}.
- Typical regimens:
- Osteoarthritis: 200 mg once daily or 100 mg twice daily
- Rheumatoid arthritis: 100–200 mg twice daily
- Acute pain/dysmenorrhea: initial 400 mg dose, then 200 mg as needed :contentReference[oaicite:7]{index=7}.
- Missed dose: Take when remembered unless nearing next dose; never double-dose :contentReference[oaicite:8]{index=8}.
- Duration: Use lowest effective dose for shortest duration; monitor symptoms to evaluate ongoing need :contentReference[oaicite:9]{index=9}.
- Monitoring: Regularly check blood pressure, renal/liver function, and watch for GI bleeding or edema during chronic therapy :contentReference[oaicite:10]{index=10}.
- Patient advice: Avoid other NSAIDs; inform provider of all medications and supplements to avoid interactions :contentReference[oaicite:11]{index=11}.
Mode of Action ALGOXIB 200mg
ALGOXIB delivers targeted pain and inflammation relief through COX‑2 inhibition:
- Selective COX‑2 blockade: Inhibits COX‑2 enzyme responsible for inflammatory prostaglandins, while sparing COX‑1 activity that protects the stomach and platelet function :contentReference[oaicite:12]{index=12}.
- Onset: Provides pain relief typically within 1–2 hours :contentReference[oaicite:13]{index=13}.
- COX‑2 selectivity: Exhibits ~10–20-fold higher affinity for COX‑2 vs. COX‑1, reducing GI side effects :contentReference[oaicite:14]{index=14}.
- Pharmacokinetics: High protein binding (~97%); peak plasma levels at 2–4 hours; half-life ~8–12 hours; metabolized via CYP2C9, minor via CYP3A4 :contentReference[oaicite:15]{index=15}.
- Additional research: COX‑2 inhibition may restore p53-mediated tumor suppression in certain cancers, though clinical relevance remains under investigation :contentReference[oaicite:16]{index=16}.
ALGOXIB 200mg Interactions ALGOXIB 200mg
Celecoxib can interact with various medications due to pharmacodynamic and pharmacokinetic mechanisms. Be cautious and consult your healthcare provider:
- Other NSAIDs/Aspirin: Avoid concomitant use—significantly raises risk of GI bleeding and ulcers :contentReference[oaicite:21]{index=21}.
- Anticoagulants (e.g., warfarin, apixaban): May increase bleeding risk—requires close monitoring :contentReference[oaicite:22]{index=22}.
- SSRIs/SNRIs: Combined use raises GI bleeding risk :contentReference[oaicite:23]{index=23}.
- Lithium: May elevate lithium levels by reducing renal clearance—monitor serum levels :contentReference[oaicite:24]{index=24}.
- Methotrexate: Risk of bone marrow suppression increases; monitor CBC :contentReference[oaicite:25]{index=25}.
- ACE inhibitors/ARBs/diuretics: May reduce antihypertensive effects and impair kidney function :contentReference[oaicite:26]{index=26}.
- Cyclosporine: Increases nephrotoxicity risk; monitor renal function :contentReference[oaicite:27]{index=27}.
- Digoxin: Celecoxib may increase digoxin levels; monitor for toxicity :contentReference[oaicite:28]{index=28}.
- Fluconazole (CYP2C9 inhibitor): Raises celecoxib concentration—dose adjustment advised :contentReference[oaicite:29]{index=29}.
- Rifampin (enzyme inducer): Reduces celecoxib level—may lower effectiveness :contentReference[oaicite:30]{index=30}.
- Pemetrexed: Interaction increases risk of toxicity—avoid or separate by days :contentReference[oaicite:31]{index=31}.
Disclose all medications, including supplements, to your healthcare team to manage these interactions safely.
Dosage of ALGOXIB 200mg
- Osteoarthritis: 200 mg once daily or 100 mg twice daily :contentReference[oaicite:32]{index=32}.
- Rheumatoid arthritis: 100–200 mg twice daily :contentReference[oaicite:33]{index=33}.
- Ankylosing spondylitis: 200 mg once or twice daily depending on severity :contentReference[oaicite:34]{index=34}.
- Acute pain/dysmenorrhea: Initial 400 mg, then 200 mg if needed :contentReference[oaicite:35]{index=35}.
- Juvenile RA: Age/weight-based dosing for ≥2 years :contentReference[oaicite:36]{index=36}.
- Maximum: 400 mg per day; higher doses elevate risks significantly :contentReference[oaicite:37]{index=37}.
- Special populations: In elderly or hepatic/renal impairment, start with lower dose; monitor organ function closely :contentReference[oaicite:38]{index=38}.
Dosing should always strive for the minimum effective amount over the shortest practical duration to minimize risk.
Possible side effects of ALGOXIB 200mg
Celecoxib is generally well tolerated. However, awareness and surveillance for adverse effects are critical:
- Common (mild): Abdominal pain, dyspepsia, diarrhea, nausea, flatulence, headache, dizziness, upper respiratory infections :contentReference[oaicite:39]{index=39}.
- Cardiovascular: Hypertension, edema, worsening heart failure, increased risk of myocardial infarction and stroke—especially with prolonged use :contentReference[oaicite:40]{index=40}.
- Gastrointestinal: Ulcers, bleeding, or perforation in the stomach/intestines—sometimes without warning :contentReference[oaicite:41]{index=41}.
- Renal/Hepatic: Acute kidney injury, elevated liver enzymes, rarely liver failure :contentReference[oaicite:42]{index=42}.
- Dermatologic/Allergic: Rash, pruritus, possible sulfonamide reactions; rare severe skin reactions (e.g., Stevens–Johnson syndrome) :contentReference[oaicite:43]{index=43}.
- Hematologic: Anemia, unusual bleeding—risks amplified with anticoagulants or SSRIs :contentReference[oaicite:44]{index=44}.
Seek immediate medical care for signs of cardiovascular events, GI bleeding, severe skin reactions, or liver/renal impairment. Employ the lowest possible dose with routine monitoring for patients at risk.
ALGOXIB 200mg Contraindications ALGOXIB 200mg
- Absolute contraindications:
- Known allergy to celecoxib, sulfonamides, other NSAIDs, or aspirin-induced asthma/urticaria :contentReference[oaicite:45]{index=45}.
- During or immediately before coronary artery bypass graft (CABG) surgery :contentReference[oaicite:46]{index=46}.
- Active gastrointestinal bleeding or ulcer disease :contentReference[oaicite:47]{index=47}.
- Severe heart failure, uncontrolled hypertension :contentReference[oaicite:48]{index=48}.
- Severe hepatic impairment (Child-Pugh C) :contentReference[oaicite:49]{index=49}.
- Pregnancy ≥20 weeks—risk of fetal ductus arteriosus closure :contentReference[oaicite:50]{index=50}.
- Relative precautions:
- History of cardiovascular disease, stroke, or GI bleeding
- Chronic kidney disease or concomitant nephrotoxic drugs
- Older adults (>65 years): use lower starting doses :contentReference[oaicite:51]{index=51}.
- Asthma worsened by NSAIDs
- Breastfeeding: weigh benefits vs. unknown risks :contentReference[oaicite:52]{index=52}.
- Juvenile RA patients ≥2 years only—other uses are off-label :contentReference[oaicite:53]{index=53}.
Contraindications aim to prevent severe adverse events; always conduct a thorough medical evaluation before initiating treatment.
Storage of ALGOXIB 200mg
- Temperature: Store at controlled room temperature—20–25 °C (68–77 °F); avoid prolonged exposure above 30 °C or below 15 °C :contentReference[oaicite:54]{index=54}.
- Packaging: Keep capsules in their original airtight blister packs to protect from moisture and light.
- Safety: Store out of reach of children and pets.
- Expiry and disposal: Discard unused or expired capsules per local medication disposal guidelines. Do **not** flush down the toilet or throw in household trash :contentReference[oaicite:55]{index=55}.
Correct storage maintains the medication’s potency, effectiveness, and safety for patient use.
ALGOXIB 200mg features an exceptional active ingredient renowned for its potent effects, comprising Celecoxib. This powerful formulation provides a superior solution for addressing diverse health concerns. With 200mg/Capsule concentration and an easily manageable Capsules (Hard Gelatin), it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ALGOXIB 200mg .
Welcome to Dwaey, specifically on ALGOXIB 200mg page.
This medicine contains an important and useful components, as it consists of Celecoxib.
ALGOXIB 200mg is available in the market in concentration 200mg/Capsule and in the form of Capsules (Hard Gelatin).
GLOBALPHARMA CO. L.L.C. is the producer of ALGOXIB 200mg and it is imported from UAE,
The most popular alternatives of ALGOXIB 200mg are listed downward .
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Frequently Asked Questions
ALGOXIB 200mg should be stored according to the instructions provided by GLOBALPHARMA CO. L.L.C..
In general, it is recommended to store ALGOXIB 200mg in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ALGOXIB 200mg may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ALGOXIB 200mg for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ALGOXIB 200mg. Some medications, including
ALGOXIB 200mg, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ALGOXIB 200mg, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ALGOXIB 200mg without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ALGOXIB 200mg if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ALGOXIB 200mg during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 200mg/Capsule,
and the specific recommendations of GLOBALPHARMA CO. L.L.C..
The effects of ALGOXIB 200mg on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 200mg/Capsule, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ALGOXIB 200mg with or without food may vary depending on the medication
and the recommendations of GLOBALPHARMA CO. L.L.C.. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ALGOXIB 200mg in children or elderly individuals may depend on various factors, including
the specific medication, type Capsules (Hard Gelatin), and the recommendations of GLOBALPHARMA CO. L.L.C.. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ALGOXIB 200mg in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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