What is ALFRESED 30 mg/5 ml
ALFRESED is an oral liquid formulation containing Alimemazine (also known as trimeprazine tartrate), a first-generation phenothiazine derivative with antihistamine, sedative, and antiemetic properties. Each 5 ml dose delivers 30 mg of active drug, and it’s supplied in a 100 ml amber glass bottle, accompanied by an oral dosing syringe for accurate measurement.
- Generic Name: Alimemazine (trimeprazine)
- Form: Oral syrup/suspension
- Strength: 30 mg per 5 ml
- Packaging: 100 ml amber glass bottle + 5 ml syringe
- Pharmacological Class: First-generation antihistamine (H1 antagonist) with sedative‑anticholinergic effects
ALFRESED is indicated for:
- Symptomatic relief of severe allergic manifestations (urticaria, pruritus)
- Short-term management of insomnia or agitation in adults and older children
- Adjunctive therapy in nausea/vomiting
Because of its sedative properties, ALFRESED is often used off-label in pediatric practice for sleep or restless conditions, but only under strict medical oversight due to potential behavioral and respiratory side effects.
How to use ALFRESED 30 mg/5 ml
ALFRESED syrup must be used carefully and according to medical instructions. Due to its sedative effect, dosing time and monitoring are crucial.
- Preparation:
- Shake the bottle well before dosing to evenly distribute ingredients.
- Use the provided syringe for exact measurement.
- Administration Guidelines:
- Administer slowly, directly into the mouth, to ensure accurate dosage.
- Can be given with water or juice if needed to improve taste.
- Timing: For sedation or sleep support, administer 30–60 minutes before bedtime.
- Duration: Use only for short periods (typically up to 7–10 days); longer use requires re-evaluation by a healthcare provider.
- Missed Dose: If a dose is missed, give it when remembered unless it’s near the time for the next dose—do not double doses.
- Monitoring: Observe for excessive drowsiness, respiratory changes, or paradoxical agitation, especially in pediatric or older adult populations.
Only use ALFRESED under medical supervision; self-prescribing for sleep or allergy relief is discouraged.
Mode of Action ALFRESED 30 mg/5 ml
Alimemazine, the active ingredient in ALFRESED, is a multi‑receptor blocking agent with the following pharmacological effects:
- H1 Histamine Receptor Blockade: Prevents histamine binding in peripheral tissues, reducing itching, urticaria, and other allergic symptoms.
- CNS Depression and Sedation: Crosses the blood–brain barrier to antagonize H1 receptors in the brain, causing drowsiness and calming effects.
- Anticholinergic Effects: Blocks muscarinic receptors, decreasing secretions, but potentially causing dry mouth and urinary retention.
- Anti-nausea/Antiemetic Action: May work by blocking central muscarinic and dopamine-2 receptors, reducing nausea and vomiting.
The overall pharmacodynamic profile makes ALFRESED effective for both allergic symptom relief and short-term sedation, although the anticholinergic activity can contribute to side effects such as dryness or urinary hesitation.
ALFRESED 30 mg/5 ml Interactions ALFRESED 30 mg/5 ml
Alimemazine may interact with various medications, especially those affecting the central nervous or cardiovascular systems. Important potential interactions include:
- CNS Depressants (e.g., benzodiazepines, opioids, alcohol): Additive sedation and respiratory depression may occur; combination should be avoided or closely monitored.
- Anticholinergic Medications (e.g., atropine, ipratropium): Combined use may intensify dry mouth, urinary retention, and constipation.
- MAO Inhibitors (e.g., phenelzine, tranylcypromine): May potentiate anticholinergic and sedative effects; use cautiously or avoid.
- Cardiac Agents (e.g., antiarrhythmics, amiodarone): Risk of QT prolongation; monitor ECG if co-administered.
- CYP450 Modulators: Alimemazine is metabolized in the liver via CYP pathways—inducers or inhibitors (e.g., ketoconazole, rifampicin) may alter drug levels.
Always disclose all medications (including OTC and supplements) to healthcare providers when using ALFRESED. Adjustments or increased monitoring may be needed.
Dosage of ALFRESED 30 mg/5 ml
Dosing differs by age, indication, and patient tolerance. Always follow physician directives and adjust dosage based on therapeutic effect and side effects.
- Adults:
- Allergic conditions: 5–10 ml (30–60 mg) 3–4 times daily, adjusted for response.
- Short-term sedation: 5–10 ml at bedtime.
- Adolescents (12–18 years): Similar to adult dosing, based on body weight and symptom severity.
- Children (2–12 years):
- Allergy: 1–2 ml per year of age (up to 5 ml), 3–4 times daily.
- Sedation: 1–2 ml/kg once at bedtime (typically 5–10 ml).
- Infants under 2 years: Use only under specialist supervision; very cautious dosing.
- Elderly: Start low (e.g., 5 ml at bedtime) to avoid over-sedation.
Maximum duration is usually 7–10 days; prolonged use must be supervised to minimize anticholinergic effects and sedation.
Possible side effects of ALFRESED 30 mg/5 ml
ALFRESED can cause various adverse reactions depending on dose and duration. Both common and rare side effects are important to recognize:
- Common:
- Drowsiness, sedation
- Dry mouth, nose, or throat
- Mild dizziness
- Gastrointestinal discomfort
- Less Common:
- Constipation, urinary retention
- Blurred vision
- Headache, confusion (especially in elderly)
- Hypotension or palpitations
- Rare or Serious:
- Severe respiratory depression in overdose or with other CNS depressants
- Cardiac arrhythmias (QT prolongation)
- Agranulocytosis, blood dyscrasias
- Allergic reactions (rash, swelling, anaphylaxis)
Monitor closely in vulnerable individuals (elderly, children, respiratory or cardiac illness). Discontinue and seek medical attention immediately if serious side effects occur.
ALFRESED 30 mg/5 ml Contraindications ALFRESED 30 mg/5 ml
ALFRESED should not be used in the following situations:
- Known hypersensitivity: Allergy to alimemazine or phenothiazines.
- Severe respiratory conditions: Sleep apnea, severe COPD—increased risk of sedation-related breathing issues.
- Comatose states: Due to risk of further CNS depression.
- Agranaulocytosis or severe bone marrow suppression: Potential hematologic worsening.
- Sensitive populations: Newborns, preterm infants, or children with immature respiratory drive.
Use with caution (with monitoring) in elderly, those with cardiac disease, urinary retention, glaucoma, or prostatic hypertrophy causing retention.
Storage of ALFRESED 30 mg/5 ml
Proper storage ensures efficacy and safety:
- Temperature: Store at controlled room temperature (15–25 °C / 59–77 °F). Avoid freezing.
- Light Protection: Keep the amber bottle tightly closed and away from direct sunlight.
- Childproofing: Keep out of reach/sight of children and secure the cap after use.
- Expiration: Discard after the printed expiry date; solution may degrade over time.
- Hygiene: Do not touch the syringe tip or leave the bottle open; avoid contamination.
- Disposal: Dispose of unused syrup and syringes per local pharmaceutical waste guidelines.
Proper storage maintains potency, prevents microbial growth, and protects against accidental ingestion.
ALFRESED 30 mg/5 ml features an exceptional active ingredient renowned for its potent effects, comprising Alimemazine. This powerful formulation provides a superior solution for addressing diverse health concerns. With 30 mg/5 ml concentration and an easily manageable Syrup, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about ALFRESED 30 mg/5 ml .
Welcome to Dwaey, specifically on ALFRESED 30 mg/5 ml page.
This medicine contains an important and useful components, as it consists of Alimemazine.
ALFRESED 30 mg/5 ml is available in the market in concentration 30 mg/5 ml and in the form of Syrup.
SYRI LIMITED (TRADING AS THAME LABORATORIES OR SYRIMED) is the producer of ALFRESED 30 mg/5 ml and it is imported from UK,
The most popular alternatives of ALFRESED 30 mg/5 ml are listed downward .
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Active Substance
-
Size
100ml Amber Glass Bottle + 5ml Oral Syringe
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Indications
- No indications available.
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Type
-
Company
SYRI LIMITED (TRADING AS THAME LABORATORIES OR SYRIMED)
Frequently Asked Questions
ALFRESED 30 mg/5 ml should be stored according to the instructions provided by SYRI LIMITED (TRADING AS THAME LABORATORIES OR SYRIMED) .
In general, it is recommended to store ALFRESED 30 mg/5 ml in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with ALFRESED 30 mg/5 ml may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking ALFRESED 30 mg/5 ml for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking ALFRESED 30 mg/5 ml. Some medications, including
ALFRESED 30 mg/5 ml, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of ALFRESED 30 mg/5 ml, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking ALFRESED 30 mg/5 ml without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking ALFRESED 30 mg/5 ml if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of ALFRESED 30 mg/5 ml during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 30 mg/5 ml,
and the specific recommendations of SYRI LIMITED (TRADING AS THAME LABORATORIES OR SYRIMED) .
The effects of ALFRESED 30 mg/5 ml on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 30 mg/5 ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking ALFRESED 30 mg/5 ml with or without food may vary depending on the medication
and the recommendations of SYRI LIMITED (TRADING AS THAME LABORATORIES OR SYRIMED) . Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of ALFRESED 30 mg/5 ml in children or elderly individuals may depend on various factors, including
the specific medication, type Syrup, and the recommendations of SYRI LIMITED (TRADING AS THAME LABORATORIES OR SYRIMED) . Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of ALFRESED 30 mg/5 ml in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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