AIRONYL 1.5mg/5ml Syrup (Sugar-free)

What is AIRONYL 1.5mg/5ml

AIRONYL 1.5mg/5ml Syrup is a sugar-free oral liquid formulation that contains Terbutaline sulfate as its active ingredient. It is primarily prescribed as a bronchodilator to manage and relieve symptoms associated with respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchitis.

• Terbutaline sulfate belongs to the class of beta-2 adrenergic receptor agonists.
• It acts by relaxing the muscles of the airways, making breathing easier for patients with obstructive airway disorders.
• The syrup is specially formulated to be sugar-free, making it suitable for diabetic patients and those requiring low-sugar treatments.
• It is typically used in both pediatric and adult patients under medical supervision.
• Each 5ml of syrup contains 1.5mg of Terbutaline sulfate, offering a controlled and measurable dose.

This medication is commonly used in symptomatic treatment rather than long-term control and should be combined with other therapy as directed by a healthcare provider.

How to use AIRONYL 1.5mg/5ml

Proper use of AIRONYL Syrup ensures the maximum therapeutic benefit while minimizing side effects. It is essential to follow your doctor’s or pharmacist’s instructions strictly.

• Dosage should be measured using a dosing spoon or oral syringe provided by the pharmacist.
• Shake the bottle well before each use to ensure even distribution of the active ingredient.
• The syrup can be taken with or without food. However, taking it after meals may reduce gastrointestinal discomfort.
• Follow the dosing frequency prescribed—typically 2 to 3 times daily based on the severity of symptoms and age.
• Do not exceed the recommended dose, as this may increase the risk of adverse effects such as palpitations or tremors.
• If a dose is missed, take it as soon as possible, but skip it if it’s almost time for the next dose—never double the dose.
• Use the syrup regularly for the best results, and continue even if symptoms improve unless advised otherwise.

Consult your physician if symptoms worsen or do not improve within a few days of starting therapy.

Mode of Action AIRONYL 1.5mg/5ml

Terbutaline sulfate, the active component in AIRONYL, is a selective beta-2 adrenergic receptor agonist with a direct effect on the smooth muscles of the airways.

• When administered, Terbutaline binds to beta-2 receptors in the bronchial smooth muscle.
• This binding activates adenylate cyclase, increasing intracellular cyclic AMP (cAMP) levels.
• cAMP leads to a cascade of intracellular events that result in smooth muscle relaxation, particularly in the airways.
• Relaxation of bronchial muscles allows air passages to widen (bronchodilation), facilitating easier breathing.
• Additionally, Terbutaline may inhibit the release of inflammatory mediators like histamine and leukotrienes from mast cells, reducing airway inflammation.
• The onset of action usually begins within 30 minutes after oral intake and may last for up to 4–6 hours.

This mechanism makes AIRONYL ideal for acute episodes of bronchospasm but not suitable as a sole treatment for long-term asthma control.

AIRONYL 1.5mg/5ml Interactions AIRONYL 1.5mg/5ml

Drug interactions can affect how AIRONYL Syrup works or increase the risk of serious side effects. Always inform your doctor of all medications you're taking.

• Beta-blockers (e.g., propranolol, atenolol): May reduce the bronchodilating effect of Terbutaline and provoke bronchospasm.
• MAO inhibitors and tricyclic antidepressants: May enhance the cardiovascular effects of Terbutaline.
• Diuretics and corticosteroids: Concurrent use may lead to increased risk of hypokalemia (low potassium levels).
• Other sympathomimetics (e.g., salbutamol, epinephrine): Concomitant use may increase the risk of cardiovascular side effects such as tachycardia and hypertension.
• Digitalis glycosides (e.g., digoxin): Increased risk of cardiac arrhythmias when combined with Terbutaline.
• Antidiabetic drugs: Terbutaline may cause hyperglycemia, potentially reducing the efficacy of insulin or oral antidiabetic agents.

Always consult your healthcare provider before starting or stopping any medication while using AIRONYL Syrup.

Dosage of AIRONYL 1.5mg/5ml

The dosage of AIRONYL depends on the patient's age, weight, medical condition, and response to treatment. Always follow your doctor’s prescribed dose.

• Adults: Typically 10ml (3mg of Terbutaline) two or three times daily.
• Children (6–12 years): Usually 5ml to 10ml, two or three times daily, based on body weight and tolerance.
• Children (2–6 years): 2.5ml to 5ml two to three times daily. Use should be under strict medical supervision.
• Children under 2 years: Not routinely recommended unless specifically prescribed.

Note: The syrup contains 1.5mg of Terbutaline per 5ml, so accurate measurement is important to avoid overdosing. Dosage may need to be adjusted in patients with renal or hepatic impairment.

Possible side effects of AIRONYL 1.5mg/5ml

While AIRONYL Syrup is generally well-tolerated, it can cause side effects in some patients, particularly at higher doses or with prolonged use.

• Common side effects:
  • Tremors (especially of hands)
  • Headache
  • Nervousness or restlessness
  • Palpitations or increased heart rate (tachycardia)
  • Nausea
• Less common effects:
  • Muscle cramps
  • Sleep disturbances
  • Dizziness
  • Increased blood glucose
• Rare but serious effects:
  • Severe allergic reactions (rash, itching, swelling, difficulty breathing)
  • Cardiac arrhythmias
  • Chest pain (angina-like symptoms)

If you experience any unusual or severe symptoms, seek immediate medical advice.

AIRONYL 1.5mg/5ml Contraindications AIRONYL 1.5mg/5ml

AIRONYL Syrup should not be used in certain medical conditions where the risk of adverse effects outweighs potential benefits.

• Known hypersensitivity to Terbutaline or any excipients in the formulation.
• Severe cardiovascular disorders, such as arrhythmias or recent myocardial infarction.
• Uncontrolled hyperthyroidism: Due to risk of exaggerated sympathomimetic response.
• Severe hypertension: The drug may elevate blood pressure further.
• Pregnancy (especially 1st trimester): Use only when clearly needed, as Terbutaline may affect uterine tone.
• Seizure disorders: Use cautiously as stimulation of the CNS may provoke seizures.

Always inform your doctor about your full medical history before using AIRONYL Syrup.

Storage of AIRONYL 1.5mg/5ml

Proper storage conditions are essential to maintain the efficacy and safety of the medication.

• Store at a controlled room temperature between 15°C to 30°C (59°F to 86°F).
• Keep the bottle tightly closed and protected from excessive moisture, heat, or direct sunlight.
• Do not freeze the syrup.
• Keep out of reach of children and pets.
• Check the expiry date before use. Discard any remaining syrup after the expiry date.
• Once opened, follow the manufacturer’s instructions for how long the syrup can be used safely.

Proper storage ensures the stability of the active ingredient and prevents microbial contamination.