LISINOGLEN 5 Tablets

What is LISINOGLEN 5

LISINOGLEN 5 is a prescription tablet that contains Lisinopril 5 mg, an angiotensin-converting enzyme (ACE) inhibitor. It is used primarily for treating hypertension (high blood pressure), congestive heart failure, and for improving survival following a myocardial infarction (heart attack). It also helps prevent kidney damage in people with diabetes.

• Active Ingredient: Lisinopril
• Drug Class: ACE Inhibitors
• Strength: 5 mg per tablet
• Indications: High blood pressure, heart failure, diabetic nephropathy, post-heart attack management

By inhibiting the action of the ACE enzyme, LISINOGLEN 5 reduces the formation of angiotensin II, a substance that narrows blood vessels. This leads to vasodilation (widening of blood vessels), reduced blood pressure, and lower cardiac workload.

How to use LISINOGLEN 5

Take LISINOGLEN 5 exactly as directed by your healthcare provider. It is typically taken once daily.

• Swallow the tablet whole with a glass of water
• May be taken with or without food
• Take at the same time every day
• Do not discontinue without consulting your doctor

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Avoid doubling the dose.

Mode of Action LISINOGLEN 5

Lisinopril acts by blocking the conversion of angiotensin I to angiotensin II via inhibition of the angiotensin-converting enzyme (ACE). This has several beneficial effects:

• Relaxes and dilates blood vessels
• Lowers systemic vascular resistance
• Reduces blood pressure
• Improves cardiac output in heart failure patients
• Helps preserve kidney function in diabetics

The effects contribute to a reduction in cardiovascular risk and better overall circulatory health.

LISINOGLEN 5 Interactions LISINOGLEN 5

LISINOGLEN 5 may interact with other medications. Some interactions may enhance the risk of adverse effects:

• Potassium supplements or potassium-sparing diuretics: May increase the risk of hyperkalemia (high potassium levels)
• NSAIDs (e.g., ibuprofen): May reduce antihypertensive effects and impair kidney function
• Diuretics (e.g., hydrochlorothiazide): May increase the risk of hypotension
• Lithium: Risk of lithium toxicity
• Other antihypertensives: Additive hypotensive effect

Always inform your doctor of all medications, including over-the-counter drugs and supplements.

Dosage of LISINOGLEN 5

The dosage of LISINOGLEN 5 varies based on the condition being treated and the patient's health status:

• For Hypertension: Initial dose is often 5–10 mg once daily; may be increased based on response
• For Heart Failure: Starting dose may be 2.5–5 mg, increased gradually
• Post-Heart Attack: May begin with 5 mg and titrate as tolerated
• For Kidney Protection in Diabetics: Dosing depends on kidney function and proteinuria

Dosage adjustments are required in patients with kidney impairment or those on diuretics.

Possible side effects of LISINOGLEN 5

Although LISINOGLEN 5 is generally well-tolerated, some patients may experience side effects:

• Common: Dizziness, dry cough, fatigue, headache
• Less Common: Rash, nausea, decreased appetite
• Serious (rare): Angioedema (facial swelling), kidney dysfunction, hyperkalemia

Seek immediate medical attention if you notice facial swelling, difficulty breathing, or severe dizziness.

LISINOGLEN 5 Contraindications LISINOGLEN 5

• Known hypersensitivity to lisinopril or any ACE inhibitor
• History of angioedema related to previous ACE inhibitor use
• Pregnancy (especially second and third trimester)
• Use with aliskiren in diabetic patients

Caution is advised in patients with liver disease, severe renal impairment, or collagen vascular diseases.

Storage of LISINOGLEN 5

• Store at temperatures below 30°C in a dry place
• Keep tablets in original packaging
• Protect from moisture and light
• Keep out of reach of children

Do not use after the expiration date printed on the package.