LISINOGLEN 20 Tablets

What is LISINOGLEN 20

LISINOGLEN 20 is a prescription oral tablet containing Lisinopril, a widely used angiotensin-converting enzyme (ACE) inhibitor. It is primarily prescribed for the treatment of high blood pressure (hypertension), chronic heart failure, and for improving survival after a heart attack (myocardial infarction). It is also effective in protecting kidney function in patients with diabetes who have proteinuria (excessive protein in urine).

• Generic Name: Lisinopril
• Therapeutic Class: ACE Inhibitor
• Strength: 20 mg per tablet
• Main Uses: Hypertension, heart failure, post-heart attack care, and kidney protection

By relaxing blood vessels and reducing fluid retention, LISINOGLEN 20 lowers blood pressure and helps the heart pump more efficiently. It reduces the risk of cardiovascular complications such as stroke and heart failure, especially in high-risk patients.

How to use LISINOGLEN 20

LISINOGLEN 20 should be taken exactly as prescribed by your healthcare provider. It is generally taken once a day, preferably at the same time daily.

• Swallow the tablet whole with water
• May be taken with or without food
• Do not stop taking it without consulting your doctor
• Monitor your blood pressure regularly

If a dose is missed, take it as soon as remembered. However, if it’s near the time for the next dose, skip the missed dose. Do not double the dose.

Mode of Action LISINOGLEN 20

Lisinopril blocks the action of angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to angiotensin II — a hormone that causes blood vessels to narrow. This inhibition leads to:

• Relaxation and widening of blood vessels
• Reduction in blood pressure
• Decreased workload on the heart
• Improved cardiac output and kidney function

This mechanism is especially beneficial for individuals with hypertension, heart failure, or diabetic kidney disease.

LISINOGLEN 20 Interactions LISINOGLEN 20

Drug interactions can influence how LISINOGLEN 20 works or increase the risk of side effects. Key interactions include:

• Potassium supplements and potassium-sparing diuretics (e.g., spironolactone): May raise potassium levels excessively
• Diuretics (e.g., furosemide): May enhance the blood pressure-lowering effect
• NSAIDs (e.g., ibuprofen): Can reduce effectiveness and impair kidney function
• Lithium: May increase lithium toxicity
• Other antihypertensives: Additive effect leading to hypotension

Always inform your doctor about all prescription and over-the-counter drugs and supplements you are taking.

Dosage of LISINOGLEN 20

Dosage should be individualized based on the medical condition and response:

• Hypertension: Maintenance dose is typically 10–40 mg once daily; LISINOGLEN 20 is often used as a full daily dose or titrated up to 40 mg
• Heart failure: May start with 2.5–5 mg and increase gradually under supervision
• Post-myocardial infarction: Typically starts at lower doses and increases based on tolerance
• Kidney impairment: Lower starting doses and careful monitoring are advised

The exact dosage must always be determined by your physician.

Possible side effects of LISINOGLEN 20

While LISINOGLEN 20 is generally well-tolerated, it can cause side effects in some people:

• Common: Dizziness, dry cough, headache, fatigue
• Less Common: Nausea, rash, changes in taste
• Serious (Rare): Angioedema (swelling of face/lips/tongue), severe hypotension, hyperkalemia, kidney dysfunction

Seek medical help immediately if you experience symptoms of an allergic reaction, especially facial swelling or difficulty breathing.

LISINOGLEN 20 Contraindications LISINOGLEN 20

• Known hypersensitivity to Lisinopril or other ACE inhibitors
• History of angioedema associated with prior ACE inhibitor therapy
• Pregnancy (especially 2nd and 3rd trimester)
• Concomitant use with aliskiren in diabetic patients

Caution is advised in patients with impaired renal function or collagen vascular disease.

Storage of LISINOGLEN 20

• Store in a cool, dry place below 30°C
• Keep tablets in original blister packs to protect from moisture
• Keep away from direct sunlight and heat
• Keep out of reach of children

Do not use the medication beyond the expiry date printed on the pack.