LISINO 20mg Tablets/Film-coated

What is LISINO 20mg

LISINO 20 mg is a film-coated oral tablet containing Lisinopril, a potent and long-acting ACE (Angiotensin-Converting Enzyme) inhibitor. It is commonly prescribed to manage hypertension (high blood pressure), treat heart failure, and improve survival after certain cardiac events such as myocardial infarction. It may also be used to protect the kidneys in patients with diabetes and proteinuria.

• Drug Class: ACE Inhibitor (Antihypertensive agent)
• Generic Name: Lisinopril
• Strength: 20 mg per tablet
• Indications: Hypertension, congestive heart failure, post-heart attack recovery, diabetic nephropathy

By blocking ACE, LISINO 20 mg prevents the conversion of angiotensin I to angiotensin II, a chemical that narrows blood vessels. This leads to vasodilation, reduced blood pressure, and decreased workload on the heart.

How to use LISINO 20mg

LISINO 20 mg should be taken exactly as prescribed by a healthcare professional. It is usually taken once daily, at the same time each day.

• Take the tablet by mouth with water
• Can be taken with or without food
• Do not double the dose if one is missed; take the next dose at the scheduled time
• Continue taking it even if you feel well, as high blood pressure often has no symptoms

Monitoring your blood pressure, kidney function, and potassium levels regularly during treatment is crucial.

Mode of Action LISINO 20mg

Lisinopril inhibits the enzyme ACE, which is responsible for converting angiotensin I into angiotensin II.

• Decreases angiotensin II production → vasodilation
• Reduces aldosterone secretion → less sodium and water retention
• Lowers blood pressure and reduces strain on the heart
• Improves blood flow and oxygen delivery to vital organs

These mechanisms also help in reducing symptoms of heart failure and preventing further heart damage post-infarction.

LISINO 20mg Interactions LISINO 20mg

LISINO 20 mg may interact with several medications, necessitating caution or dosage adjustment:

• Diuretics: Increased risk of low blood pressure or electrolyte imbalance
• Potassium supplements / potassium-sparing diuretics: May cause hyperkalemia
• NSAIDs: Can reduce effectiveness and potentially harm kidneys
• Lithium: Risk of lithium toxicity due to reduced excretion
• Other antihypertensives: Can increase the blood pressure-lowering effect

Always inform your healthcare provider about all medicines and supplements you are taking.

Dosage of LISINO 20mg

• Hypertension: Maintenance dose commonly 20 mg once daily
• Heart failure: Starting dose often 2.5–5 mg, increased as tolerated to 20–40 mg daily
• Post-myocardial infarction: Initial low dose increased gradually to 20 mg daily
• Renal impairment: Lower starting doses may be recommended; monitor renal function regularly

Never adjust your dose without consulting a healthcare provider.

Possible side effects of LISINO 20mg

While many people tolerate LISINO 20 mg well, side effects may occur:

• Common: Cough, dizziness, fatigue, headache
• Less common: Nausea, rash, taste disturbances
• Serious: Angioedema (swelling of face/lips/tongue), high potassium, kidney dysfunction

Seek medical help immediately if you experience difficulty breathing or facial swelling.

LISINO 20mg Contraindications LISINO 20mg

• Hypersensitivity to lisinopril or other ACE inhibitors
• History of angioedema associated with previous ACE inhibitor use
• Pregnancy (especially in the 2nd and 3rd trimesters)
• Severe kidney dysfunction without proper supervision
• Use with aliskiren in patients with diabetes or renal impairment

Storage of LISINO 20mg

• Store below 30°C (86°F)
• Keep the medication in its original blister packaging
• Protect from excessive heat, moisture, and direct sunlight
• Keep out of reach of children